Low expression of chloride channel accessory 1 predicts a poor prognosis in colorectal cancer

© 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. Funded by Friends of ANCHOR NHS Grampian Endowment Fund. Grant Number: 12/50Peer reviewedPublisher PD

Breast cancer risk and imprinting methylation in blood

Date of Acceptance: 17/08/2015 Acknowledgements This study was supported by the Breast Cancer Campaign (2008MayPR46) and Fraserburgh Moonlight Prowl Breast Cancer Charity. PH, GH and GWH acknowledge the support of the Scottish Government. We would like to thank Val Bain and Michela Donnarumma for help with the data and sample collection.Peer reviewedPublisher PD

Guidelines, guidelines and more guidelines: And we still do not know how to follow-up patients with breast cancer

BACKGROUND: A major challenge facing us is the provision of health care and appropriate allocation of available resources for the treatment of patients with breast cancer. This is of particular concern in the provision of follow-up care. With the increasing incidence of breast cancer and the improvements in survival which have resulted in up to 75% of patients surviving for more than five years, an increasing resource is required. However, there is controversy as to the most appropriate schedule for follow-up of these patients. This brief review has focused on the evidence-base and guidelines that currently exist in the United Kingdom for the follow-up of patients who have been treated for breast cancer. METHODS: A review of the current guidelines published in the United Kingdom for the follow-up of patients with breast cancer (National Institute for Clinical Excellence, Scottish Intercollegiate Guidelines Network, British Association of Surgical Oncology) and the randomised controlled trials evaluating the follow-up of patients with breast cancer was undertaken. RESULTS: The results have demonstrated the different follow-up protocols currently indicated in these guidelines within the same country. Furthermore, the lack of well designed, randomised controlled trials on which to base a follow-up protocol for patients with breast cancer is apparent. CONCLUSION: The evidence-base on which these guidelines have been developed is lacking. It is apparent that well designed randomised controlled trials are needed urgently if we are to understand the most appropriate and effective ways of following up patients with breast cancer

q-Space Imaging Yields a Higher Effect Gradient to Assess Cellularity than Conventional Diffusion-weighted Imaging Methods at 3.0 T : A Pilot Study with Freshly Excised Whole-Breast Tumors

N.S. supported by Biotechnology and Biological Sciences Research Council (1654748, BB/M010996/1). Study supported by the National Health Service Grampian Endowment Fund (15/1/052).Peer reviewedPublisher PD

Optimal Phased-Array Signal Combination For Polyunsaturated Fatty Acids Measurement In Breast Cancer Using Multiple Quantum Coherence MR Spectroscopy At 3T

Acknowledgements The author would like to thank Dr Matthew Clemence (Philips Healthcare Clinical Science, UK) for clinical scientist support, Ms Bolanle Brikinns, Ms Louisa Pirie, Ms Linda Lett, and Ms Kate Shaw for patient recruitment support, Ms Dawn Younie for logistic support, Mr Roger Bourne and Ms Mairi Fuller for providing access to the patients as well as Mrs Beverly MacLennan, Mrs Nichola Crouch, Mr Mike Hendry, and Ms Laura Reid for radiographer support. This project was funded by Friends of Aberdeen and North Centre for Haematology, Oncology and Radiotherapy (ANCHOR). Vasiliki Mallikourti’s PhD study is supported by The Princess Royal Tenovus Scotland Medical Research Scholarship.Peer reviewedPublisher PD

Phased-array combination of 2D MRS for lipid composition quantification in patients with breast cancer

Acknowledgements: The author would like to thank Dr Matthew Clemence (Philips Healthcare Clinical Science, UK) for clinical scientist support, Ms Bolanle Brikinns, Ms Louisa Pirie, Ms Linda Lett, and Ms Kate Shaw, for patient recruitment support, Ms Dawn Younie for logistic support, Mr Roger Bourne and Ms Mairi Fuller for providing access to the patients as well as Mrs Beverly MacLennan, Mrs Nicola Crouch, Mr Mike Hendry, and Ms Laura Reid for radiographer support. Funding: This project was funded by Friends of Aberdeen and North Centre for Haematology, Oncology and Radiotherapy (ANCHOR), Tenovus Scotland, and NHS Grampian Endowment. Vasiliki Mallikourti’s PhD study is supported by The Princess Royal Tenovus Scotland Medical Research Scholarship.Peer reviewedPublisher PD