Rheology of the gel formed in the California Mastitis Test

The California Mastitis Test has previously been adapted for use in an inline, cow-side sensor and relies on the fact that the viscosity of the gel formed during the test is proportional to the somatic cell concentration. In this paper, the use of capillary and rotational viscometry was compared in light of the expected rheology of the gel formed during the test. It was found that the gel is non-Newtonian, but the initial phase of viscosity increase was not due to shear dependence, but rather due to the gelation reaction. The maximum apparent viscosity of the gel was shear dependent while the time it took to reach the maximum was not truly shear dependent, but was rather dependent on the degree of mixing during gelation. This was confirmed by introducing a delay time prior to viscosity measurement, in both capillary and rotational viscometry. It was found that by mixing the reagent and infected milk, then delaying viscosity measurement for 30 s, shortened the time it took to reach maximum viscosity by more than 60 s. The maximum apparent viscosity, however, was unaffected. It was found that capillary viscometry worked well to correlate relative viscosity with somatic cell count, but that it was sensitive to the reagent concentration. It can therefore be deduced that the rheology of the gel is complicated not only by it being non-Newtonian, but also by the strong dependence on test conditions. These make designing a successful sensor much more challenging

Impact of contractor internal tendering procedure governance on tender win-rates: How procedures can be improved

Construction contractors normally, though not always, pursue tenders with the expectation of winning and subsequently making a project profit. Corporate governance (CG) constraints, risk appetite, and selected tender strategy impact contractors' tendered prices and any associated qualifications. Therefore, failure to win may not constitute 'failure' in senior executive's eyes. Increasing CG within some jurisdictions has led to more complicated contractor internal tendering procedures (ITP) with layers of management reviews and risk committee sign-offs. The question arises as to whether these changes make any difference to tender win rates and subsequent project outcomes. A series of qualitative semi-structured interviews were undertaken with 25 high-profile Australasian based construction contractors (11, either directly or via parent companies, operate internationally-Europe, Africa, Asia and North America), providing a mix of publicly listed and privately owned companies, as part of a wider research program investigating the efficiency and effectiveness of contractors' ITP. Moving beyond previous research limitations of smaller contractors (often sub-AU$100m turnover) this qualitative research looks at much larger contractors. Content analyses of the interview transcripts found that, while contractors talked equally about 'win' and 'lose', most did not see losing a tender as 'failure'. Only a quarter felt their changed ITP made a difference to their tender win-rate. Somewhat unexpectedly interview findings suggest that approximately three-quarters of contractors have ITP that do not formally require lessons learned (LL) from previous tenders nor projects to be inputs in subsequent tender pursuits. Larger contractors (over AU$500m turnover) were twice as likely to discuss LL, indicating different governance approaches to tender outcome expectations. Informal LL approaches were applied to clients' reputations (particularly payment) in bid/no-bid decisions. Interviewee suggestions of processes by which contractors can improve resultantly their LL procedures, as part of their CG, are also presented

Rethinking the tendering frameworks of construction contractors in the context of a soft systems methodology approach

Limited research has been conducted on the internal tendering procedures (ITP) of construction contractors because of the commercially sensitive and confidential nature of the subject matter. This limitation explains the reluctance of contractors to undergo interviews. Existing research (outside bid/no-bid and margin decision factor identification and subsequent decision modeling development) only begins to provide insights into key tendering stages, particularly around risk assessments and corporate review processes. Early research suggested one to three review stages. However, when considering the whole work procurement process from prospect identification to contract execution, five to seven series of reviews can be arguably applied by some contractors, wherein some reviews stepped through several layers of internal senior management. Tendering processes were presented as flowchart models that traditionally follow “hard” system (rectangular shapes and straight line arrows) steps, which suggest that a precise process also leads to precise results. However, given that contractors do not win every tender they submit, the process is less precise than that suggested in rigidly structured flowcharts. Twenty-five detailed semi-structured interviews were held with purposely selected high-profile publicly and privately owned construction companies in Australia with significantly varied turnovers. Analyses show that contractors are concerned about the negative effects of increasing corporate governance demands, with many stating that people involved are the most critical element to tendering success. A new way of presenting the ITP of contractors is assessed using a soft systems methodology (SSM) approach. SSM offers an alternative way of considering human interaction challenges within the ITP of contractors, which needs to be tested with the industry. The format graphics of SSM guidelines are presented as a way of offering contractors a different approach, which may assist individuals who are looking to re-structure their tendering activities in a more humanistic and less rigid procedural approach

Austronesian prehistory and Polynesian genetics

The migration into and settlement of remote Oceania by the modern Polynesian and Māori peoples is a major achievement, which has been the subject of extensive research and scholarship. The routes taken by the Austronesian peoples and the origins of the migrations are subject to ongoing debate. We present a range of findings from molecular genetic studies of Polynesian and New Zealand Māori populations and a ‘synthetic total evidence theory’ that we suggest can account for key elements of the migrations

Medical students' experience of personal loss: incidence and implications.

BACKGROUND: Medical students are generally young people, often away from home for the first time and undertaking a course in which they are learning to care for people at all stages of life, including those approaching death. Existing research indicates that their experiences of personal bereavement may have significant implications for their pastoral welfare and medical learning. No previous studies have tracked medical student experience of bereavement longitudinally and no recent data are available from the UK. AIMS: The study aims to identify medical students' experience of personal bereavement: the prevalence prior to and during the course and their relationship with those who died. METHOD: Paper and online questionnaire including questions about recent personal loss. SETTING / PARTICIPANTS: Four cohorts of core science and clinical medical students at the University of Cambridge, 1021 participants in total. RESULTS: Mean response rate was 65.2% for core science students and 72.8% for clinical students. On entry to the core science course, 23.1% of all students had experienced a loss at some point. Between 13.0% and 22.5% experienced bereavement during years 1 - 5 of the course: some (1.3% - 6.3%) experienced multiple or repeated losses. Close deaths reported were most commonly those of grandparents followed by friends. CONCLUSIONS: Medical students commonly experience close personal bereavement, both before and during their course. Educators need to be aware of the range of personal and educational implications of bereavement for medical students, and ensure that appropriate help is available. Further research could explore incidence of loss at other medical schools and investigate the impact and depth of experience of loss.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are