Virtual Reconstruction and Morphological Analysis of the Cranium of an Ancient Egyptian Mummy

A mummy of an Egyptian priestess dating from the 22nd dynasty (c. 770 BC), completely enclosed in an anthropoid (human shaped) coffin, was scanned on a CT scanner. An accurate reconstruction of the cranium was generated from 115 × 2 mm CT images using AVS/Express on a SGI computer. Linear measurements were obtained from six orthogonal cranial views and used in a morphometric analysis software package (CRANID). The analyses carried out were both linear and nearest neighbour discriminant analysis. The results show that there is a 52.9% probability that the mummy is an Egyptian female, with a 24.5% probability that mummy is an African female. Thus the technique confirms that the coffin contains an Egyptian female, which is consistent with the inscription on the coffin and the shape of the pelvic bones as revealed by plain X-rays. These results show that this technique has potential for analysing forensic cases where the bones are obscured by soft tissue and clothing. This technique may have an application in virtual autopsies

LIVESTOCK FUTURES MARKETS AND RATIONAL PRICE FORMATION: EVIDENCE FOR LIVE CATTLE AND LIVE HOGS

The efficiency of livestock futures markets continues to receive attention, particularly with regard to their forward pricing or forecasting ability. The purpose of this paper is to present a more general theory that encompasses the forward pricing concept. It is argued that futures contract prices for competitively produced nonstorable commodities, such as live cattle and live hogs, follow a rational formation process. Futures contract prices reflect expected market conditions when contracts are sufficiently close to the delivery month that the supply of the underlying commodity cannot be changed. However, prior to the period when future supplies are relatively fixed, futures contract prices should adjust to reflect the competitive equilibrium, where output price equals average costs of production. Presented evidence suggests that live cattle and live hog futures markets support the rational price formation hypothesis: prices for distant contracts reflect average costs of feeding. Implications for risk management strategies are considered.Demand and Price Analysis, Livestock Production/Industries,

Purification and characterization of mouse hypoxanthine-guanine phosphoribosyltransferase.

Journal ArticleHypoxanthine-guanine phosphoribosyltransferase (HGPR transferase) (EC 2.4.2.8) has been purified approximately 4500-fold to apparent homogeneity from mouse liver. The procedure involves the use of affinity chromatography and was designed to be readily adaptable to small scale isolations. The enzyme appears to be composed of 3 subunits of identical molecular weight (27,000 per subunit). The subunit molecular weight has also been determined by the analysis of radioactively labeled HGPR transferase immunoprecipitated from wild type and mutant (HGPR transferase) mouse tissue culture cell lines

Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro.

Journal ArticletRNA isolated from two different yeast super-suppressor strains translates a known nonsense mutation in vitro, whereas tRNA from a closely related nonsuppressing strain does not. Suppression was assayed by translation of RNA isolated from an amber coat mutant of bacteriophage Qbeta (GB11) in a protein-synthesizing system derived from mouse tissue culture cells (L cells). Suppressed forms of Qbeta coat protein synthesized in vitro were quantitatively detected by a specific immunoprecipitation assay. The L-cell protein-synthesizing system also responds to E. coli suppressor tRNA. This indicates that the biochemical mechanism for nonsense suppression is very similar in yeast and E. coli. These findings also provide additional evidence that the amber codon (UAG) functions as one of the mammalian chain-terminating codons. Since the suppression assay utilizes protein-synthesizing components isolated from mammalian cells, it should prove useful in the search for mammalian nonsense suppressor

Selective degradation of abnormal proteins in mammalian tissue culture cells.

Journal ArticleThe degradation rates of several missense mutants of hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) in mouse L cells are compared to those of the wild-type enzyme. Although the rates of total protein breakdown in the mutant cell lines are identical to that of the parental L cell line, defective molecules of hypoxanthine-guanine phosphoribosyltransferase present in the mutant cell lines are degraded much faster than the wild-type enzyme. The level of defective phosphoribosyltransferase molecules present in the mutant cell lines is inversely proportional to the breakdown rate. This observation indicates that the major factor determining the concentrations of the defective phosphoribosyltransferases is their specific degradation rate. These results strongly support the hypothesis that abnormal proteins are selectively degraded in mammalian cells

Some Inconvenient Truths About Climate Change Policy: The Distributional Impacts of Transportation Policies

Instead of efficiently pricing greenhouse gases, policy makers have favored measures that implicitly or explicitly subsidize low carbon fuels. We simulate a transportation-sector cap & trade program (CAT) and three policies currently in use: ethanol subsidies, a renewable fuel standard (RFS), and a low carbon fuel standard (LCFS). Our simulations confirm that the alternatives to CAT are quite costly—2.5 to 4 times more expensive. We provide evidence that the persistence of these alternatives in spite of their higher costs lies in the political economy of carbon policy. The alternatives to CAT exhibit a feature that make them amenable to adoption|a right skewed distribution of gains and losses where many counties have small losses, but a smaller share of counties gain considerably—as much as $6,800 per capita, per year. We correlate our estimates of gains from CAT and the RFS with Congressional voting on the Waxman-Markey cap & trade bill, H.R. 2454. Because Waxman-Markey (WM) would weaken the RFS, House members likely viewed the two policies as competitors. Conditional on a district's CAT gains, increases in a district's RFS gains are associated with decreases in the likelihood of voting for WM. Furthermore, we show that campaign contributions are correlated with a district's gains under each policy and that these contributions are correlated with a Member's vote on WM.Institute of Transportation Studies at UC Davi

Hyperinnervation Produces Inhibitory Interactions between Two Taste Nerves a

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74872/1/j.1749-6632.1987.tb43629.x.pd

The Design of a Sterile Product Laboratory Module as Preparation for an Institutional IPPE Course

Objectives: To develop a pharmaceutics laboratory module on compounded sterile products for the second year pharmacy students as preparation for an institutional pharmacy experiential course. Method: A 5-week lab module was designed and implemented as part of the Pharmaceutics Lab Course to provide training in the basic skills of sterile product compounding. The module included techniques in the handling of sterile products, aseptic techniques, medium risk products, and hazardous products. A practical exam was given at the end of this module to ensure student competency. Upon completion of the lab module, students enrolled in a required 4-week institutional pharmacy experiential course (IPPE-2), where students were required to compound a minimum of 10 sterile products. Students were then asked to participate in a survey assessing the effectiveness and relevance of the lab module as preparation for their IPPE-2. Results: The sterile product lab module was offered in the spring semester with 75 students enrolled. All students passed the sterile product lab module and continued onto the IPPE-2 course during the following summer. The student survey indicated that the students felt well prepared for the IPPE-2 and that the preceptors were satisfied with their prior training in sterile compounding. The average scores ranged from 4.8 - 6.5 (scale of 1-7) for the various products addressed in the lab module. Implications: The 5-week sterile product lab module progressively prepares the students with the basic skills and knowledge in compounding sterile products. This preparedness allows the students to transition smoothly into the subsequent institutional pharmacy experiential course. Copyright © 2011 American Association of Colleges of Pharmac