Incorporation of glycine-2-C-14 in acid-insoluble proteins of rat bones and teeth during hypokinesia and administration of thyrocalcitonine

A forced limitation of the motor activity in rats (from 5 to 60 days) results in reduced incorporation of glycine 2-C14 in the total acid insoluble proteins of limb bones and its increase in the teeth and mandibular-maxillary bones. Daily administration of five micrograms of thyrocalcitonine together with polyvinylpyrrolidone normalizes the protein metabolism in the bone tissues during the 40 days of experimentation

Effects of solar magnetic field on cosmic rays

Aspects of the problem of galactic cosmic ray propagation, including inversion of the solar total magnetic field and an analysis of data related to the heliomagnetic cycle are discussed. It is noted that the global structure of the solar magnetic field results in an additional flux of galactic cosmic rays generated by curvature and gradient drifts. An analysis of heliomagnetic cycle data shows that the latitudinal gradient results in a N-S asymmetry, with the amplitude of the effect growing with depth in the atmosphere. The inversion of the solar total magnetic field, drift effects, and other space distributions are found to contribute to a 22-year cycle of solar activity

Scrub typhus ecology: a systematic review of Orientia in vectors and hosts

Abstract Scrub typhus, caused by Orientia tsutsugamushi, is an important and neglected vector-borne zoonotic disease with an expanding known distribution. The ecology of the disease is complex and poorly understood, impairing discussion of public health interventions. To highlight what we know and the themes of our ignorance, we conducted a systematic review of all studies investigating the pathogen in vectors and non-human hosts. A total of 276 articles in 7 languages were included, with 793 study sites across 30 countries. There was no time restriction for article inclusion, with the oldest published in 1924. Seventy-six potential vector species and 234 vertebrate host species were tested, accounting for over one million trombiculid mites (‘chiggers’) and 83,000 vertebrates. The proportion of O. tsutsugamushi positivity was recorded for different categories of laboratory test and host species. Vector and host collection sites were geocoded and mapped. Ecological data associated with these sites were summarised. A further 145 articles encompassing general themes of scrub typhus ecology were reviewed. These topics range from the life-cycle to transmission, habitats, seasonality and human risks. Important gaps in our understanding are highlighted together with possible tools to begin to unravel these. Many of the data reported are highly variable and inconsistent and minimum data reporting standards are proposed. With more recent reports of human Orientia sp. infection in the Middle East and South America and enormous advances in research technology over recent decades, this comprehensive review provides a detailed summary of work investigating this pathogen in vectors and non-human hosts and updates current understanding of the complex ecology of scrub typhus. A better understanding of scrub typhus ecology has important relevance to ongoing research into improving diagnostics, developing vaccines and identifying useful public health interventions to reduce the burden of the disease.</jats:p

Clinical cases of colonic torsions in patients with inborn anatomic variants

The clinic, diagnosis and treatment of two cases of dolichocolon torsions are represented: a women 31 and a men 34 years old. The represented clinical observations show diagnostic difficulties encountered in patients with congenital malformations of the colon