698 research outputs found

    Post-Lecture Discussion

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    International Law in Comparative Perspective. Edited by William E. Bytler

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    What might a comparative perspective upon international law mean, or reveal? The phrase evokes the tradition of Comparative Law with its related methods and purposes. That tradition is rooted in the study of national legal systems. Scholars within one such system explore another or several others--a cross-cultural inquiry serving both practical and broad scholarly aims. However illuminating, these explorations cannot be viewed as indispensable to the study of national law. They stand at the periphery rather than core of most students\u27 or scholars\u27 concerns. Does a comparative method within international law serve a similarly confined purpose? Or should we understand it as more central and pervasive a phenomenon, even vital to a threshold inquiry into the nature, norms and processes for development of international law? Such are the questions stimulated by this useful book

    Social Rights and Economic Development: Converging Discourses?

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    Pressures and Principles - The Politics of the Antiboycott Legislation

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    Efficient room temperature aqueous Sb2S3 synthesis for inorganic-organic sensitized solar cells with 5.1% efficiencies.

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    Sb2S3 sensitized solar cells are a promising alternative to devices employing organic dyes. The manufacture of Sb2S3 absorber layers is however slow and cumbersome. Here, we report the modified aqueous chemical bath synthesis of Sb2S3 absorber layers for sensitized solar cells. Our method is based on the hydrolysis of SbCl3 to complex antimony ions decelerating the reaction at ambient conditions, in contrast to the usual low temperature deposition protocol. This simplified deposition route allows the manufacture of sensitized mesoporous-TiO2 solar cells with power conversion efficiencies up to Ī· = 5.1%. Photothermal deflection spectroscopy shows that the sub-bandgap trap-state density is lower in Sb2S3 films deposited with this method, compared to standard deposition protocols.Cambridge Trust, the Mott Fund for Physics of the Environment and Corpus Christi College Cambridge for funding. A.S. acknowledges funding from the Engineering and Physical Sciences Research Council (EPSRC).This is the final version. It first appeared at http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/c5cc01966d#!divAbstract

    Microscale to Manufacturing Scale-up of Cell-Free Cytokine Productionā€”A New Approach for Shortening Protein Production Development Timelines

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    Engineering robust protein production and purification of correctly folded biotherapeutic proteins in cell-based systems is often challenging due to the requirements for maintaining complex cellular networks for cell viability and the need to develop associated downstream processes that reproducibly yield biopharmaceutical products with high product quality. Here, we present an alternative Escherichia coli-based open cell-free synthesis (OCFS) system that is optimized for predictable high-yield protein synthesis and folding at any scale with straightforward downstream purification processes. We describe how the linear scalability of OCFS allows rapid process optimization of parameters affecting extract activation, gene sequence optimization, and redox folding conditions for disulfide bond formation at microliter scales. Efficient and predictable high-level protein production can then be achieved using batch processes in standard bioreactors. We show how a fully bioactive protein produced by OCFS from optimized frozen extract can be purified directly using a streamlined purification process that yields a biologically active cytokine, human granulocyte-macrophage colony-stimulating factor, produced at titers of 700 mg/L in 10 h. These results represent a milestone for in vitro protein synthesis, with potential for the cGMP production of disulfide-bonded biotherapeutic proteins. Biotechnol. Bioeng. 2011; 108:1570ā€“1578. Ā© 2011 Wiley Periodicals, Inc

    Necessary fictions: indigenous claims and the humanity of rights

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    Indigenous right insistently challenges the surpassing arrogations of sovereign right. In so doing, it affirms dimensions of being-together denied or stunted in sovereign modes of political formation. This force of Indigenous right is amplified here through legal and literary instantiations. These, in turn, uncover the continuously created and fictional quality of rights, revealing them to be necessary fictions
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