2,580 research outputs found

    Thermal Kinetic Inductance Detectors for Millimeter-Wave Astrophysics

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    Thermal Kinetic Inductance Detectors (TKIDs) combine the excellent noise performance of traditional bolometers with a radio frequency (RF) multiplexing architecture that enables the large detector counts needed for the next generation of millimeter-wave instruments. Here we present dark prototype TKID pixels that demonstrate a noise equivalent power NEP = 2×10⁻¹⁷√W/Hz with a 1/f knee at 0.1 Hz, suitable for background-limited noise performance at 150 GHz from a ground-based site. We discuss the optimizations in the device design and fabrication techniques to realize optimal electrical performance and high quality factors at a bath temperature of 250 mK

    CD4+ and πσT Cells are the main Producers of IL-22 and IL-17A in Lymphocytes from Mycobacterium bovis-infected Cattle

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    Gene transcription studies have identified dual roles for the cytokines IL-17A and IL-22 in bovine tuberculosis, where they show potential as both predictors of vaccine success and correlates of infection. To allow for a detailed investigation of the cell populations responsible for production of these cytokines, we have utilised a novel bovine IL-22 specific recombinant antibody for flow cytometry. Bovine tuberculin (PPDB) induced greater IL-22 and IL-17A production in Mycobacterium bovis (M. bovis)-infected cattle compared to non-infected controls, while PWM-induced cytokine levels were similar between the two groups. In M. bovis-infected animals, PPDB specific IL-22 and IL-17A responses were observed in both CD4+ T cell and γδ T cell populations. Although both cytokines were detected in both cell types, IL-22/IL-17A double producers were rare and confined mainly to the γδ T cell population. These results support previous gene transcription studies and extend the observation of increased IL-22 and IL-17A responses in M. bovis-infected animals to the level of protein production. We were also able to characterise the cell populations responsible for these disease-related cytokine responses. The data generated can be used to further our understanding of the immunopathology of bovine tuberculosis and to produce more sensitive and specific immune-diagnostic reagents

    Stochastic Cutoff Method for Long-Range Interacting Systems

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    A new Monte-Carlo method for long-range interacting systems is presented. This method consists of eliminating interactions stochastically with the detailed balance condition satisfied. When a pairwise interaction VijV_{ij} of a NN-particle system decreases with the distance as rijαr_{ij}^{-\alpha}, computational time per one Monte Carlo step is O(N){\cal O}(N) for αd\alpha \ge d and O(N2α/d){\cal O}(N^{2-\alpha/d}) for α<d\alpha < d, where dd is the spatial dimension. We apply the method to a two-dimensional magnetic dipolar system. The method enables us to treat a huge system of 2562256^2 spins with reasonable computational time, and reproduces a circular order originated from long-range dipolar interactions.Comment: 18 pages, 9 figures, 1 figure and 1 reference are adde

    Time Budget on Major Activities of Livestock Grazing Heterogeneous Natural Range and Crop Fields in Semi-Arid Nigeria

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    Semi-arid rangelands of West Africa provide herbs, trees and shrubs, which together with crop residues form the main sources of feed for the livestock population. Feed supply in this region is characterised by a progressive decline in quantity and quality with advancing dry season. It was reported that walking ability as well as watering frequencies affect the productivity of grazing livestock (Dicko and Sangare, 1984). This study tests the hypothesis that advancing season increases both time spent walking as well as feeding, with a switch from grazing to browsing

    Roughness gradient induced spontaneous motion of droplets on hydrophobic surfaces: A lattice Boltzmann study

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    The effect of a step wise change in the pillar density on the dynamics of droplets is investigated via three-dimensional lattice Boltzmann simulations. For the same pillar density gradient but different pillar arrangements, both motion over the gradient zone as well as complete arrest are observed. In the moving case, the droplet velocity scales approximately linearly with the texture gradient. A simple model is provided reproducing the observed linear behavior. The model also predicts a linear dependence of droplet velocity on surface tension. This prediction is clearly confirmed via our computer simulations for a wide range of surface tensions.Comment: 6 pages, 8 figure

    Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat

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    Case summary A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE). The cat’s clinical signs resolved, but 6 months later it was diagnosed as having an anaplastic astrocytoma and was euthanased. Serum anti-Müllerian hormone (AMH) concentration prior to OHE was increased vs a control group of entire and neutered female cats. Following OHE, serum AMH concentration decreased to <1% of the original value. Relevance and novel information Serum AMH measurement may represent a novel diagnostic and monitoring tool for functional ovarian neoplasms in cats

    ПРОУЧВАНЕ НА ХИМИЧНАТА НЕЕДНОРОДНОСТ НА КАДМИЙ И ОЛОВО В БИОСФЕРАТА - БИОАКУМУЛАЦИЯ НА КАДМИЙ И ОЛОВО В ОРГАНИЗМА НА МЛАДИ ПРЕЖИВНИ ЖИВОТНИ ОТ АНТРОПОГЕННИ ЕКОСИСТЕМИ С ПОВИШЕН ТЕХНОГЕНЕН КЛАРК

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    The technogenic Clarc of lead (Pb) and cadmium (Cd) from the upper soil layer and the forage plants in an industrially polluted region, so as the Pb and Cd input in the organism of young lambs and kid by the synthesis of secondary biological production have been investigated. For the synthesis of 1 kg secondary production in the organism of lambs, the input of Pb with the food and drinking water is 6.44 mg and 2.46 mg Cd and in the kid- organism- 21.41 mg Pb and 5.29 mg Cd. The obtained production in conditions of increased technogenic Clarc is with higher content of Pb and Cd, according the maximal admissible levels (EC- regulation 466/2001).Изследвани са технологичният кларк на олово и кадмий в горе н слой на почва и фуражи в индустриално замърсен район, както и постъпленията на олово и кадмий в организма на млади агнета и ярета при синтеза на вторична биологична продукция. За синтеза на 1 kg вторична продукция при агнета, постъпленията от фуража и питейната вода са 6,44 mg олово и 2,46 mg кадмий а в организма на яретата – съответно 21,41 mg олово и 5,29 mg кадмий. Получената в условията на повишен техногенен кларк продукция е с по високо съдържание на олово и кадмий спрямо пределнодопустимите концинтрации (EC regulation 466/2001)

    ПРОУЧВАНЕ НА ХИМИЧНАТА НЕЕДНОРОДНОСТ НА КАДМИЙ И ОЛОВО В БИОСФЕРАТА - БИОАКУМУЛАЦИЯ НА КАДМИЙ И ОЛОВО В ОРГАНИЗМА НА МЛАДИ ПРЕЖИВНИ ЖИВОТНИ ОТ АНТРОПОГЕННИ ЕКОСИСТЕМИ С ПОВИШЕН ТЕХНОГЕНЕН КЛАРК

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    The technogenic Clarc of lead (Pb) and cadmium (Cd) from the upper soil layer and the forage plants in an industrially polluted region, so as the Pb and Cd input in the organism of young lambs and kid by the synthesis of secondary biological production have been investigated. For the synthesis of 1 kg secondary production in the organism of lambs, the input of Pb with the food and drinking water is 6.44 mg and 2.46 mg Cd and in the kid- organism- 21.41 mg Pb and 5.29 mg Cd. The obtained production in conditions of increased technogenic Clarc is with higher content of Pb and Cd, according the maximal admissible levels (EC- regulation 466/2001).Изследвани са технологичният кларк на олово и кадмий в горе н слой на почва и фуражи в индустриално замърсен район, както и постъпленията на олово и кадмий в организма на млади агнета и ярета при синтеза на вторична биологична продукция. За синтеза на 1 kg вторична продукция при агнета, постъпленията от фуража и питейната вода са 6,44 mg олово и 2,46 mg кадмий а в организма на яретата – съответно 21,41 mg олово и 5,29 mg кадмий. Получената в условията на повишен техногенен кларк продукция е с по високо съдържание на олово и кадмий спрямо пределнодопустимите концинтрации (EC regulation 466/2001)
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