Управление подбором менеджеров среднего звена в организации (на материале деятельности ООО "ИНКОМ АВТО")

Цель исследования - разработать рекомендации по организации подбора менеджеров среднего звена в ООО "ИНКОМ АВТО". Объект - управление персоналом в ООО "ИНКОМ АВТО". В результате исследования были рассмотрены теоретические основы организации подбора и отбора персонала, рассмотрен подбор персонала как функция управления и область влияния на деятельность компании.The purpose of the research is to develop recommendations on the organization of selection of mid-level managers in INCOM AUTO LLC. Object - personnel management in OOO INCOM AUTO. As a result of the research, the theoretical foundations of the organization of recruitment and selection of personnel were considered, the selection of personnel as a function of management and the scope of influence on the company's activities were considered

Oxidative destruction of organic pollutants on modified polypropylene fiber

The paper shows the prospects of using composites based on polypropylene fiber with embedded particles of metal Fe{0} and Al{0}. Samples were used for oxidative destruction of organic compounds under conditions of the Fenton-like system and visible radiation

Stress hormones: cortisol, adrenocorticotropic hormone and oxytocin in the context of social violations in children with autism spectrum disorders

Autism spectrum disorders (ASD) refer to heterogeneous disorders of neurodevelopment, the main symptom of which is social insufficiency. Aim: to conduct a one-stage assessment of the relationship between key hormones in the regulation of social and stress responses: adrenocorticotropic hormone (ACTH), cortisol, oxytocin, in children with ASD in the context of severe social insufficiency. Materials and methods. A total of 44 children (37 boys and 7 girls) aged 3 to 12 years with a diagnosis of ASD were examined, which were divided into groups: with preserved social contact / lack of it. The concentrations of hormones were evaluated in blood plasma by the method of ELISA. Results. ACTH and cortisol demonstrate interdependent relationships without the involvement of oxytocin in children with ASD, while maintaining their social contact. In children with ASD with symptoms of social insufficiency, there are no correlations between the studied neurohormones. The conclusion. The data obtained suggest that the processes of disorganization / destruction of neuroanatomical and physiological connections between the systems of oxytocin and the hypothalamic-pituitary-adrenal axis (HPA-axis) and (or) the hypothalamic-neurohypophysis system and the HPA-axis

Микротвердость валиков из бронзы ПГ-19М-01, нанесенных как составляющая мултимодального покрытия методом лазерной наплавки

В статье рассматриваются преимущества лазерной наплавки и возможности использования лазерной наплавки для создания мультимодальных покрытий из разнородных металлических материалов. Приведены результаты исследований микротвердости в поперечном сечении наплавленных валиков из алюминиевой бронзы. Показано влияние скорости лазерной наплавки на микротвердость в наплавленных валиках.The advantages and the capabilities of laser cladding are analyses for used laser cladding for applying multimodal coatings from heterogeneous metal work materials. Results of microhardness investigations in cross section of cladding tracks from Al-bronze are exhibited. The influence of cladding velocity on microhardness are examined

Обоснование выбора электродвигателя и схемы его включения для системы точного поддержания скорости

Рассматривается применение в системах точного поддержания скорости различных синхронных электродвигателей. В результате сравнения рекомендовано применение в таких системах конденсаторного синхронного реактивного двигателя с трехфазными обмотками статора. Это позволяет упростить и удешевить систему точного электропривода и повысить ее надежность

Пигменты для окрашивания строительных материалов

Получены керамические пигменты с использованием техногенного кремнезёмсодержащего отхода - ванадиевого катализатора. В составе пигментов наряду с преобладающей фазой муллита идентифицируется корунд. По результатам рентгенофазового анализа установлено, что оксиды хрома и железа встраиваются в структуру вплоть до концентрации 10 мас. % и не выделяются в свободном виде. В кобальтсодержащих пигментах образуется шпинель CoAl2O4. Разработанные пигменты выдерживают температуру обжига 1200 ?С, их можно рекомендовать для получения керамических красок, цветных глазурей, для окрашивания строительных материалов

Sequential (gemcitabine/vinorelbine) and concurrent (gemcitabine) radiochemotherapy with FDG-PET-based target volume definition in locally advanced non-small cell lung cancer: first results of a phase I/II study

BACKGROUND: The aim of the study was to determine the maximal tolerated dose (MTD) of gemcitabine every two weeks concurrent to radiotherapy, administered during an aggressive program of sequential and simultaneous radiochemotherapy for locally advanced, unresectable non-small cell lung cancer (NSCLC) and to evaluate the efficacy of this regime in a phase II study. METHODS: 33 patients with histologically confirmed NSCLC were enrolled in a combined radiochemotherapy protocol. 29 patients were assessable for evaluation of toxicity and tumor response. Treatment included two cycles of induction chemotherapy with gemcitabine (1200 mg/m(2)) and vinorelbine (30 mg/m(2)) at day 1, 8 and 22, 29 followed by concurrent radiotherapy (2.0 Gy/d; total dose 66.0 Gy) and chemotherapy with gemcitabine every two weeks at day 43, 57 and 71. Radiotherapy planning included [(18)F] fluorodeoxyglucose positron emission tomography (FDG PET) based target volume definition. 10 patients were included in the phase I study with an initial gemcitabine dose of 300 mg/m(2). The dose of gemcitabine was increased in steps of 100 mg/m(2 )until the MTD was realized. RESULTS: MTD was defined for the patient group receiving gemcitabine 500 mg/m(2 )due to grade 2 (next to grade 3) esophagitis in all patients resulting in a mean body weight loss of 5 kg (SD = 1.4 kg), representing 8% of the initial weight. These patients showed persisting dysphagia 3 to 4 weeks after completing radiotherapy. In accordance with expected complications as esophagitis, dysphagia and odynophagia, we defined the MTD at this dose level, although no dose limiting toxicity (DLT) grade 3 was reached. In the phase I/II median follow-up was 15.7 months (4.1 to 42.6 months). The overall response rate after completion of therapy was 64%. The median overall survival was 19.9 (95% CI: [10.1; 29.7]) months for all eligible patients. The median disease-free survival for all patients was 8.7 (95% CI: [2.7; 14.6]) months. CONCLUSION: After induction chemotherapy, the maximum tolerated dose and frequency of gemcitabine was defined at 500 mg/m(2 )every two weeks in three cycles during a maximum of 7 weeks of thoracic radiotherapy for the phase II study. This regimen represents an effective and tolerable therapy in the treatment of NSCLC