Faktor yang Berhubungan dengan Pernikahan Dini di Kelurahan Pangli Kecamatan Sesean Kabupaten Toraja Utara

The young age of marriage is the marriage performed by a woman aged 16 years while for men was 19 years (according to the Act No. 1 Year 1974). According to the guidelines of BKKBN, the ideal marriage is a marriage performed by a man - men with at least 25 years of age and women at least 20 years of age. Approximately 25% of the population married early age. In pangli, North of Toraja regency in 2007 there were 28.21% who did early marriage. The research objective was to analyze factors related to early marriage in pangli, North of Toraja. This research was conducted in pangli, Sesean, North of Toraja Regency. This research was a descriptive cross sectional design styudy. From a population of 263 with simple random sampling method obtained 68 samples. Analysis was performed by an analysis of univariate and bivariate (biva-riate descriptive using cross tabulation and bivariate analytic by using chi square test and T-independent), the research instruments used were questionnaires. The results from all respondents who did early marriage (82.4%), low knowledge scores (41.2%) lower education (83.8%), low income (89.7%), family members numbered more than five people (73.5%), pregnant teenagers (73.5%). Hail statistical test showed no relationship between knowledge (p-value = 0.041), education (p-value = 0.000), income (p-value = 0.024), number of family members (p-value = 0.042), adolescent pregnancy (p- value = 0.006) against early marriage. Couples advised to fertile age in order to im-plement family planning programs, especially in limiting the number of births (stoping).Key Words: Early Marriag

Accounting for Comorbidity in Assessing the Burden of Epilepsy Among US Adults: Results from the National Comorbidity Survey Replication (NCS-R)

Although epilepsy is associated with substantial role impairment, it is also highly comorbid with other physical and mental disorders, making unclear the extent to which impairments associated with epilepsy are actually due to comorbidities. This issue was explored in the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey of 5,692 US adults. Medically-recognized epilepsy was ascertained with self-report, comorbid physical disorders with a chronic conditions checklist, and comorbid DSM-IV mental disorders with the Composite International Diagnostic Interview (CIDI). Lifetime epilepsy prevalence was estimated at 1.8%. Epilepsy was comorbid with numerous neurological and general medical conditions and with a sporadic cluster of mental comorbidities (panic, PTSD, conduct disorder, and substance use disorders). Although comorbid disorders explain part of the significant gross associations of epilepsy with impairment, epilepsy remains significantly associated with work disability, cognitive impairment, and days of role impairment after controlling comorbidities. The net association of epilepsy with days of role impairment after controlling for comorbidities is equivalent to an annualized 89.4 million excess role impairment days among US adults with epilepsy, arguing that role impairment is a major component of the societal costs of epilepsy per se rather than merely due to disorders comorbid with epilepsy. This estimated burden is likely conservative as some parts of the effects of epilepsy are presumably mediated by secondary comorbid disorders

Density versus chemical potential in holographic field theories

We study the relationship between charge density ({\rho}) and chemical potential ({\mu}) for an array of Lorentz invariant 3 + 1 dimensional holographic field theories with the minimal structure of a conserved charge. The systems considered include Dp-Dq probe brane constructions and probe and backreacted 'bottom-up' models with gauge and scalar fields. In all cases, at large density, the relationship is well modelled by a power law behaviour of the form {\rho} $\propto$ {\mu}^{\alpha}. A variety of powers {\alpha} are found in the brane systems while in most of the bottom-up models {\alpha} is determined by the underlying conformal symmetry. Further, it is demonstrated that basic thermodynamical and causality constraints demand {\alpha} \geq 1, a condition that was realized in each system considered.Comment: 30 pages, 3 figures, 2 table

Acción urbana: ¿acción profesional?

El debate “¿Acción urbana: acción profesional?” se celebró el 30 de abril de 2014 en el marco del programa radiofónico “¿Qué está paz-ando? Una mirada reflexiva con los actores que construyen ciudadanía”, del Instituto de Paz de la Universidad Distrital de Bogotá, (Colombia). En él se trató el tema de las acciones urbanas desde distintas visiones, con invitados tanto académicos como profesionales provenientes del I Foro Internacional de Acciones Urbanas, organizado por la Universidad de Los Andes. Se tuvo especial atención a la participación desde Twitter a través del hashtag #D_accion, transmitiendo temas y preguntas a los distintos invitado

THE PRODUCTION OF RADIOISOTOPES BY SPALLATION.

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Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

EGF, but not TGFα, efficiently induces degradation of the EGF receptor (EGFR). We show that EGFR was initially polyubiquitinated to the same extent upon incubation with EGF and TGFα, whereas the ubiquitination was more sustained by incubation with EGF than with TGFα. Consistently, the ubiquitin ligase c-Cbl was recruited to the plasma membrane upon activation of the EGFR with EGF and TGFα, but localized to endosomes only upon activation with EGF. EGF remains bound to the EGFR upon endocytosis, whereas TGFα dissociates from the EGFR. Therefore, the sustained polyubiquitination is explained by EGF securing the kinase activity of endocytosed EGFR. Overexpression of the dominant negative N-Cbl inhibited ubiquitination of the EGFR and degradation of EGF and EGFR. This demonstrates that EGF-induced ubiquitination of the EGFR as such is important for lysosomal sorting. Both lysosomal and proteasomal inhibitors blocked degradation of EGF and EGFR, and proteasomal inhibitors inhibited translocation of activated EGFR from the outer limiting membrane to inner membranes of multivesicular bodies (MVBs). Therefore, lysosomal sorting of kinase active EGFR is regulated by proteasomal activity. Immuno-EM showed the localization of intact EGFR on internal membranes of MVBs. This demonstrates that the EGFR as such is not the proteasomal target