Radiocarbon dates from the Oxford AMS system: archaeometry datelist 35

This is the 35th list of AMS radiocarbon determinations measured at the Oxford Radiocarbon Accelerator Unit (ORAU). Amongst some of the sites included here are the latest series of determinations from the key sites of Abydos, El Mirón, Ban Chiang, Grotte de Pigeons (Taforalt), Alepotrypa and Oberkassel, as well as others dating to the Palaeolithic, Mesolithic and later periods. Comments on the significance of the results are provided by the submitters of the material

A three stage model for the inner engine of GRBs: Prompt emission and early afterglow

We describe a model within the ``Quark-nova'' scenario to interpret the recent observations of early X-ray afterglows of long Gamma-Ray Bursts (GRB) with the Swift satellite. This is a three-stage model within the context of a core-collapse supernova. STAGE 1 is an accreting (proto-) neutron star leading to a possible delay between the core collapse and the GRB. STAGE 2 is accretion onto a quark-star, launching an ultrarelativistic jet generating the prompt GRB. This jet also creates the afterglow as the jet interacts with the surrounding medium creating an external shock. Slower shells ejected from the quark star (during accretion), can re-energize the external shock leading to a flatter segment in the X-ray afterglow. STAGE 3, which occurs only if the quark-star collapses to form a black-hole, consists of an accreting black-hole. The jet launched in this accretion process interacts with the preceding quark star jet, and could generate the flaring activity frequently seen in early X-ray afterglows. Alternatively, a STAGE 2b can occur in our model if the quark star does not collapse to a black hole. The quark star in this case can then spin down due to magnetic braking, and the spin down energy may lead to flattening in the X-ray afterglow as well. This model seems to account for both the energies and the timescales of GRBs, in addition to the newly discovered early X-ray afterglow features.Comment: 4 pages, to appear in the proceedings of the HEPRO conference, September 24-28, 2007, Dublin, Irelan

Childhood intelligence and personality traits neuroticism and openness contributes to social mobility : A study in the Aberdeen 1936 Birth Cohort

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Tau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease

ACKNOWLEDGMENTS We thank patients and their caregivers for their participation in the study and are indebted to all the investigators involved in the study, particularly Drs. Douglas Fowlie and Donald Mowat for their helpful contributions to the clinical execution of the study in Scotland. We thank Sharon Eastwood, Parexel, for assistance in preparing initial drafts of the manuscript. We acknowledge constructive comments provided by Professors G. Wilcock and S. Gauthier on drafts of the article. CMW, CRH, and JMDS are officers of, and hold beneficial interests in, TauRx Therapeutics. RTS, PB, KK, and DJW are paid consultants to TauRx Therapeutics. The study was financed entirely by TauRx TherapeuticsPeer reviewedPublisher PD

Angiotensin II type 1 receptor antibodies in childhood kidney transplantation

Angiotensin II type 1 receptor antibodies (AT1 RAb) have emerged as non-HLA Ab present in patients with acute AMR and risk of graft loss. Furthermore, AT1 RAb have been shown to increase angiotensin II sensitivity which may play a role in the development of CVD and hypertension. Data on AT1 RAb in stable transplant recipients are lacking. The aim of this study was to analyze the levels of AT1 RAb in a cohort of stable patients after kidney transplantation (tx) in childhood. A cross-sectional study of 30 children (median age 14, range 3-19 yr, median time since tx five yr) and 28 adults who were transplanted in childhood (median age 26, range 20-40 yr, median time since tx 18 yr) transplanted between 1993-2006 and 1983-2002, respectively, was performed. Healthy controls were 51 healthy children (5-8 yr) and 199 healthy donors (median age 56.5 yr, range 42-83 yr). Plasma AT1 RAb were analyzed by immunoassay. Median total AT1 RAb IgG concentration was significantly higher in the pediatric-tx group as compared to the adult-tx group (40.0 and 10.95 U/mL, p < 0.0001). For both groups, the tx group showed higher levels: the pediatric-tx group vs. control group (40.0 vs. 13.3 U/mL, p = 0.0006) and the adult-tx group vs. adult control group (10.95 vs. 6.5 U/mL, p < 0.0001). Age was the strongest indicator of high levels of AT1 RAb IgG (p = 0.0003). AT1 RAb total IgG levels are significantly higher in a stable pediatric-tx cohort as compared to adult-tx patients and healthy controls of comparable age groups. The relevance of our findings in relation to age, time since tx, previous or future rejection, and CVD risk merits future studies

Successfully dating rock art in Southern Africa using improved sampling methods and new characterization and pretreatment protocols

©2016 University of Arizona. This is the Author Accepted Manuscript. Please refer to any applicable publisher terms of use.Worldwide, dating rock art is difficult to achieve because of the frequent lack of datable material and the difficulty of removing contamination from samples. Our research aimed to select the paints that would be the most likely to be successfully radiocarbon dated and to estimate the quantity of paint needed depending on the nature of the paint and the weathering and alteration products associated with it. To achieve this aim, a two-step sampling strategy, coupled with a multi-instrument characterization (including SEM-EDS, Raman spectroscopy, and FTIR spectroscopy analysis) and a modified acid-base-acid (ABA) pretreatment, was created. In total, 41 samples were dated from 14 sites in three separate regions of southern Africa. These novel protocols ensure that the 14C chronology produced was robust and could also be subsequently applied to different regions with possible variations in paint preparation, geology, weathering conditions, and contaminants

The New Zealand Kauri (Agathis Australis) Research Project: A Radiocarbon Dating Intercomparison of Younger Dryas Wood and Implications for IntCal13

We describe here the New Zealand kauri (Agathis australis) Younger Dryas (YD) research project, which aims to undertake Δ14C analysis of ~140 decadal floating wood samples spanning the time interval ~13.1–11.7 kyr cal BP. We report 14C intercomparison measurements being undertaken by the carbon dating laboratories at University of Waikato (Wk), University of California at Irvine (UCI), and University of Oxford (OxA). The Wk, UCI, and OxA laboratories show very good agreement with an interlaboratory comparison of 12 successive decadal kauri samples (average offsets from consensus values of –7 to +4 14C yr). A University of Waikato/University of Heidelberg (HD) intercomparison involving measurement of the YD-age Swiss larch tree Ollon505, shows a HD/Wk offset of ~10–20 14C yr (HD younger), and strong evidence that the positioning of the Ollon505 series is incorrect, with a recommendation that the 14C analyses be removed from the IntCal calibration database

Long-term hydromethylthionine treatment is associated with delayed clinical onset and slowing of cerebral atrophy in a pre-symptomatic P301S MAPT mutation carrier

ACKNOWLEDGMENTS We thank the patient for permitting publication of the present report. Authors’ disclosures available online (https://www.j-alz.com/manuscript-disclosures/21-0390r1).Peer reviewedPublisher PD

Physical restraint in residential child care : the experiences of young people and residential workers

There have long been concerns about the use of physical restraint in residential care. This paper presents the findings of a qualitative study which explores the experiences of children, young people and residential workers about physical restraint. The research identifies the dilemmas and ambiguities for both staff and young people, and participants discuss the situations where they feel physical restraint is appropriate as well as their concerns about unjustified or painful restraints. They describe the negative emotions involved in restraint but also those situations where, through positive relationships and trust, restraint can help young people through unsafe situations

Fermions scattering in a three dimensional extreme black hole background

The absorption cross section for scattering of fermions off an extreme BTZ black hole is calculated. It is shown that, as in the case of scalar particles, an extreme BTZ black hole exhibits a vanishing absorption cross section, which is consistent with the vanishing entropy of such object. Additionally, we give a general argument to prove that the particle flux near the horizon is zero. Finally we show that the {\it reciprocal space} introduced previously in \cite{gm} gives rise to the same result and, therefore, it could be considered as the space where the scattering process takes place in an AdS spacetime.Comment: 15 pages, RevTex4. Revised version. To be published in Class. Quantum. Gra