136 research outputs found

    A Strategic Approach to Agricultural Research Program Planning in Sub-Saharan Africa

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    Recent studies have shown that agricultural research can have high payoffs in Africa, but impact depends on how well technology fits with evolving needs and capacity in the agricultural sector and the rest of the economy. Structural adjustment policies (e.g., market liberalization, currency devaluation) and political change are transforming user demands for new technology and the economic environment in which technology must perform. The challenge is how to design agricultural research as a strategic input to promote broad-based economic growth, structural transformation, and food security in the increasingly market-driven, but fragile, economies of Africa.Food Security, Food Policy, Agricultural Research, Research and Development/Tech Change/Emerging Technologies, Downloads May 2008-July 2009: 44, Q18,

    A Strategic Approach to Agricultural Research Program Planning in Sub-Saharan Africa

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    Research and Development/Tech Change/Emerging Technologies, Downloads May 2008-July 2009: 13,

    Une approche stratégique pour la planification du programme de recherche agricole en Afrique sub-saharienne

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    Des études récentes ont montré que la recherche agricole en Afrique peut avoir une rentabilité élevée, mais son impact dépend de l'adaptabilité des nouvelles technologies aux capacités et aux besoins changeants du secteur agricole et du reste de l'économie. Les politiques d'ajustement structurel (ex : la libéralisation des marchés et la dévaluation monétaire) et les changements politiques sont en train de transformer la demande de nouvelles technologies et l'environnement économique au sein duquel ces technologies doivent opérer. Le défi est de concevoir la recherche agricole comme un intrant stratégique qui encourage une croissance économique à base élargie, la transformation structurelle de l'économie et la sécurité alimentaire dans des économies africaines de plus de plus orientées vers la production pour la commercialisation mais qui restent encore fragiles.food security, food policy, agricultural research, Research and Development/Tech Change/Emerging Technologies, Downloads June 2008-June 2009: 11, Q18,

    Влияние термомеханической обработки на структуру, механические и трибологические свойства композитов Al-Si-Sn

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    Исследование влияния режима спекания порошковых прессовок, а также последующей их деформационной обработки методом горячего доуплотнения и равноканального углового прессования (РКУП) на результирующую структуру, механические и трибологические свойства композитов (Al-Si)-40Sn.Investigation of the effect of sintering regimes of powder compacts, as well as their deformation treatment by hot doping and equal-channel angular pressing (ECAP) on the resulting structure, mechanical and tribological properties of composites (Al-Si)-40Sn

    Проектирование автоматизированной групповой замерной установки при разработке Макарьевского месторождения нефти на проточном-1 лицензионном участке недр Томской области

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    В данной дипломной работе произведено обоснование оптимальной конфигурации и проектирование автоматизированной группой замерной установки для системы сбора продукции эксплуатационных скважин в рамках прогноза эффективности разработки Макарьевского месторождения Томской области.In this graduation work the study of the optimal configuration and design of automated group measuring system for the collection system of production wells within the forecast development efficiency Makar deposits of Tomsk region

    The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation

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    Purpose: In children, data on the combined impact of age, genotype, and disease severity on tacrolimus (TAC) disposition are scarce. The aim of this study was to evaluate the effect of these covariates on tacrolimus dose requirements in the immediate post-transplant period in pediatric kidney and liver recipients. Methods: Data were retrospectively collected describing tacrolimus disposition, age, CYP3A5 and ABCB1 genotype, and pediatric risk of mortality (PRISM) scores for up to 14 days post-transplant in children receiving liver and renal transplants. Initial TAC dosing was equal in all patients and adjusted using therapeutic drug monitoring. We determined the relationship between covariates and tacrolimus disposition. Results: Forty-eight kidney and 42 liver transplant recipients (median ages 11.5 and 1.5 years, ranges 1.5-17.7 and 0.05-14.8 years, respectively) received TAC post-transplant. In both transplant groups, younger children (<5 years) needed higher TAC doses than older children [kidney: 0.15 (0.07-0.35) vs. 0.09 (0.02-0.20) mg/kg/12h, p = 0.046, liver: 0.12 (0.04-0.32) vs. 0.09 (0.01-0.18) mg/kg/12h, p
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