Skill formation and precarious labor: the historical role of the industrial training institutes in India 1950-2018

This paper explores the historical and ideological contestations over the meaning, nature and scope of industrial skill training in state-sponsored Industrial Training Institutes (ITIs) in their attempts to create a disciplined and committed labour force in India. Through a combination of conceptual insights drawn from Indian labour historiography and ethnographic participant research, the paper addresses the challenges faced by ITIs in maintaining a unified, centralized vision for industrial skill-training of workers under conditions of vastly uneven geographical development of the industrial sector and progressively intense interregional capital mobility in contemporary India

Mina Loy's PARTURITION and L'ecriture Feminine

[Abstract is not Available

Network analysis uncovers the communication structure of SARS-CoV-2 spike protein identifying sites for immunogen design

Summary: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has triggered myriad efforts to understand the structure and dynamics of this complex pathogen. The spike glycoprotein of SARS-CoV-2 is a significant target for immunogens as it is the means by which the virus enters human cells, while simultaneously sporting mutations responsible for immune escape. These functional and escape processes are regulated by complex molecular-level interactions. Our study presents quantitative insights on domain and residue contributions to allosteric communication, immune evasion, and local- and global-level control of functions through the derivation of a weighted graph representation from all-atom MD simulations. Focusing on the ancestral form and the D614G-variant, we provide evidence of the utility of our approach by guiding the selection of a mutation that alters the spike’s stability. Taken together, the network approach serves as a valuable tool to evaluate communication “hot-spots” in proteins to guide design of stable immunogens