Allyl and Benzyl Dance under Basic Conditions

International audienc

Multicomponent synthesis of fused benzimidazolopiperazines

International audienceWe present a novel protocol for the efficient synthesis of fused benzimidazolo piperazines starting from a four-component Ugi-Smiles reaction and a subsequent three-step cascade involving an acid-catalyzed cyclization, an intramolecular reductive cyclization, and an oxidation. © 2011 American Chemical Society