Procena ekološkog rizika u funkciji zaštite životne sredine

This paper proposes an appropriate methodology for ecological risk assessment. The methodology has been applied in the region of Boka Kotorska Bay (Bay), Montenegro. The emphasis of the research is on the analysis of the impact of various stressors on the ecological components of Bay. The consequences of that impact can be seen in an increased level of eutrophication of water environment, mostly through the influence of nitrogen and its compounds. The actual research at/about the region of Boka Kotorska Bay was performed in the period of 2008. The study emphasized the importance of the acquisition, processing and analysis of various ecologically related data for more efficient monitoring and management of the environment. The suggested methodology of the ecological risk assessment is, therefore, a remarkable scientific and expert contribution in the area of environmental protection in our country and in general.U radu je predstavljena primena metodologije procene ekološkog rizika. Metodologija je primenjena na primeru Bokokotorskog zaliva (Zaliv). Istraživanjem je razmatrana procena uticaja većeg broja stresora na ekološke komponente Zaliva. Posledice ovih uticaja ispoljene su kroz povećan stepen eutrofikacije vodene sredine i dovode se u vezu sa koncentracijom azotnih jedinjenja (nitrata i nitrita) Konkretna merenja vršena su u 2008. godini. Istraživanjem je posebno ukazano na značaj razvoja sistema prikupljanja i obrade ekoloških i drugih informacija radi efikasnijeg upravljanja životnom sredinom datog prostora. Primenjena metodologija procene ekološkog rizika trebalo bi da u naučnom i stručnom pogledu predstavlja doprinos u oblasti zaštite životne sredine,kako kod nas, tako i u svetu

The influence of selenium and deiodinases blockers on juvenile rats body weight

In this work there was investigated the influence of selenium and deodinases blockers on juvenile rats body weight during three months. The experiment was carried out on 64 rats divided into eight groups with eight individual animals per group. Following groups were formed: 1. Se+PTU-IA- (control group), 2. Se+PTU+IA+, 3. Se+PTU+IA-, 4. Se+PTU- IA+, 5. Se-PTU-IA-, 6. Se-PTU+IA+, 7. Se-PTU+IA- and 8. Se-PTU-IA+. The groups labeled (Se+) were selenium adequate and they were fed with food that contained 0.334 mg Se/kg. The groups labeled (Se-) were selenium deficient and obtained food with 0.031 mg Se/kg. As deiodinases blockers there were used propylthiouracil (PTU+) in a dose of 150 mg/L of drinking water and iopanoic acid (IA+) in a dose of 6 mg/100 g TM intraperitoneally. Body weight of experimental rats was measured every seven days. After three weeks of treatment there were taken blood samples of animals from all experimental groups and following parameters were determined: selenium concentration in blood, thyroxine (T4), triiodothyronine (T3) and thyroidstimulating hormone (TSH) in blood plasma. Analysis of the samples showed that the animals from the groups treated with PTU had lower body weight in regard to the control group, as well as lower concentration of T3 and T4 in plasma. Selenium deficient rats had lower average body weight compared to the selenium adequate ones after three weeks, but there were no differences in thyroid hormones concentration. The lowest average body weight was noticed in selenium deficient rats groups treated with PTU. [Projekat Ministartsva nauke Republike Srbije, br. TR31050 i br. TR31003

Uticaj selena i blokatora dejodinaza na telesnu masu juvenilnih pacova

In this work there was investigated the influence of selenium and deodinases blockers on juvenile rats body weight during three months. The experiment was carried out on 64 rats divided into eight groups with eight individual animals per group. Following groups were formed: 1. Se+PTU-IA- (control group), 2. Se+PTU+IA+, 3. Se+PTU+IA-, 4. Se+P-TU-IA+, 5. Se-PTU-IA-, 6. Se-PTU+IA+, 7. Se-PTU+IA- and 8. Se-PTU-IA+. The groups labeled (Se+) were selenium adequate and they were fed with food that contained 0.334 mg Se/kg. The groups labeled (Se-) were selenium deficient and obtained food with 0.031 mg Se/kg. As deiodinases blockers there were used propylthiouracil (PTU+) in a dose of 150 mg/L of drinking water and iopanoic acid (IA+) in a dose of 6 mg/100 g TM intraperitoneally. Body weight of experimental rats was measured every seven days. After three weeks of treatment there were taken blood samples of animals from all experimental groups and following parameters were determined: selenium concentration in blood, thyroxine (T4), triiodothyronine (T3) and thyroidstimulating hormone (TSH) in blood plasma. Analysis of the samples showed that the animals from the groups treated with PTU had lower body weight in regard to the control group, as well as lower concentration of T3 and T4 in plasma. Selenium deficient rats had lower average body weight compared to the selenium adequate ones after three weeks, but there were no differences in thyroid hormones concentration. The lowest average body weight was noticed in selenium deficient rats groups treated with PTU.U okviru ogleda je ispitivan uticaj selena i blokatora dejodinaza na telesnu masu juvenilnih pacova tokom tri nedelje. Ogled je izveden na 64 pacova podeljenih u osam grupa od po 8 jedinki. Formirane su sledeće grupe: 1. Se+PTU-IA- (kontrolna grupa), 2. Se+PTU+IA+, 3. Se+PTU+IA-, 4. Se+PTU-IA+, 5. Se-PTU-IA-, 6. Se-PTU+IA+, 7. Se-PTU+IA- i 8. Se-PTU-IA+. Grupe sa oznakom (Se+) su bile selenadekvatne i dobijale su hranu koja je sadržala 0,334 mg Se/kg hrane. Grupe sa oznakom (Se-) su bile selendeficitne i dobijale su 0,031 mg mg Se/kg hrane. Kao blokatori dejodinaza su korišćeni propiltiouracil (PTU+) u dozi od 150 mg/L vode za piće i jopanoična kiselina (IA+) u dozi od 6 mg/100g t.m. intraperitonealno. Telesna masa oglednih pacova je merena svakih sedam dana. Nakon tri nedelje tretmana uzeti su uzorci krvi životinja iz svih oglednih grupa i određivani su sledeći parametri: koncentracja selena u punoj krvi, tiroksin (T4), trijodtironin (T3) i tireostimulirajući hormon (TSH) u krvnoj plazmi. Analiza je pokazala da su jedinke iz grupe tretiranih sa PTU imale nižu telesnu masu u odnosu na kontrolnu, kao i nižu koncentraciju T3 i T4 u plazmi. Selendeficitni pacovi su nakon tri nedelje imali nižu prosečnu telesnu masu u odnosu na selenadekvatne, ali nisu uočene razlike u koncentraciji tireoidnih hormona. Najniža prosečna telesna masa zabeležena je kod selendeficitnih grupa pacova tretiranih sa PTU

Effects of radiotherapy on oral cavity tissues

Radiotherapy in the treatment of head and neck tumors is most often used as an independent method or in combination with surgery and / or chemotherapy. These therapeutic methods in a multidisciplinary approach generally lead to favourable therapeutic response. During radiotherapy of this region, oral mucosa is inevitably covered within irradiated volume. Radical therapy is achieved with high doses of radiation, which usually results in development of undesired toxic effects, which, depending on the time of manifestation can be acute and late. Acute radiation toxicity occurs during or immediately after completion of performed therapy, and the late one several months or years after the completed treatment. The most common acute complications in the oral cavity are inflammation of oral mucosa, loss of taste, dry mouth and secondary infections. Late complications include radiation caries, trismus, and osteoradionecrosis. The aim of this paper was to present the effects and specificities of toxicity observed on oral cavity tissues after radiotherapy

Antimicrobial effects of carbonaceous material functionalized with silver

Carbonaceous materials as well as its form functionalized with metallic silver have been prepared by hydrothermal carbonization of fructose. Results are presented to show that nanostructured silver was obtained through the functionalization process. The carbonaceous materials were characterized by: nitrogen adsorption/desorption measurement, XRD, SEM/EDS and FTIR. Samples functionalized with silver were analyzed by: XRD and SEM/EDS. The XRD analysis showed that the carbonaceous materials functionalized with silver by hydrothermal carbonization process were successfully performed. Size of silver particles was found to be approximately 32 nm, indicating formation of nanostructure. All samples were tested as an antimicrobial agent for water disinfection. Presence of nanostructured silver in the sample containing 1 mg/mL carbonaceous materials significantly decreased the number of CFU (dCFU = 97.33 %) if compared to the same sample containing the same amount of carbonaceous materials but without of silver (dCFU 65.33 %)

Parametarsko modelovanje srednjevekovnih portala Raških crkava

U ovom radu zasnovanom na geometrijskim pravilnostima arhitektonskog dizajna, istražuju se mogućnosti načina kreiranja digitalnih parametarskih modela portala crkava u Raškoj (srednjevekovna teritorija Srbije). U literaturi, ovi portali su prepoznati kao romanički, prema karakterističnom dizajnu i geometriji. Rad je nastavak istraživanja autora na analizama šest izabranih portala, u kontekstu njihovog arhitektonskog dizajna i geometrije. Na osnovu definisanih dimenzionih parametara i geometrije oblika elemenata jednog portala, kreirani su odgovarajući 3D modeli elemenata, kroz nekoliko faza, obradom u različitim programskim paketima. Kroz modelovanje izabranog portala pokazan je postupak koji kombinuje tri programska paketa: AutoCAD, SolidWorks i ArchiCAD. Cilj rada je doprinos u sferi kreiranja digitalnih biblioteka elemenata izabranog tipa portala, u okviru Heritage Building Information Modelling-a (HBIM-informaciono modelovanje istorijskih objekata)

Parametarsko modelovanje srednjevekovnih portala Raških crkava

U ovom radu zasnovanom na geometrijskim pravilnostima arhitektonskog dizajna, istražuju se mogućnosti načina kreiranja digitalnih parametarskih modela portala crkava u Raškoj (srednjevekovna teritorija Srbije). U literaturi, ovi portali su prepoznati kao romanički, prema karakterističnom dizajnu i geometriji. Rad je nastavak istraživanja autora na analizama šest izabranih portala, u kontekstu njihovog arhitektonskog dizajna i geometrije. Na osnovu definisanih dimenzionih parametara i geometrije oblika elemenata jednog portala, kreirani su odgovarajući 3D modeli elemenata, kroz nekoliko faza, obradom u različitim programskim paketima. Kroz modelovanje izabranog portala pokazan je postupak koji kombinuje tri programska paketa: AutoCAD, SolidWorks i ArchiCAD. Cilj rada je doprinos u sferi kreiranja digitalnih biblioteka elemenata izabranog tipa portala, u okviru Heritage Building Information Modelling-a (HBIM-informaciono modelovanje istorijskih objekata)