2,405 research outputs found

    Computer program conducts facilities utilization and occupancy survey

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    Computer program identifies the uses of all facilities and provides information on the net area in each room as well as the number and classification of people occupying them. The system also provides a means to indicate unsatisfactory work areas and may be able to be updated each month

    TutorialsELECTRONIC DOCUMENT MANAGEMENT

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    The Human Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2-CH3 Interface of Immunoglobulin G

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    Recognition of immunoglobulin G (IgG) by surface receptors for the Fc domain of immunoglobulin G (Fc{gamma}), Fc{gamma}Rs, can trigger both humoral and cellular immune responses. Two human cytomegalovirus (HCMV)-encoded type I transmembrane receptors with Fc{gamma}-binding properties (vFc{gamma}Rs), gp34 and gp68, have been identified on the surface of HCMV-infected cells and are assumed to confer protection against IgG-mediated immunity. Here we show that Fc{gamma} recognition by both vFc{gamma}Rs occurs independently of N-linked glycosylation of Fc{gamma}, in contrast with the properties of host Fc{gamma}Rs. To gain further insight into the interaction with Fc{gamma}, truncation mutants of the vFc{gamma}R gp68 ectodomain were probed for Fc{gamma} binding, resulting in localization of the Fc{gamma} binding site on gp68 to residues 71 to 289, a region including an immunoglobulin-like domain. Gel filtration and biosensor binding experiments revealed that, unlike host Fc{gamma}Rs but similar to the herpes simplex virus type 1 (HSV-1) Fc receptor gE-gI, gp68 binds to the CH2-CH3 interdomain interface of the Fc{gamma} dimer with a nanomolar affinity and a 2:1 stoichiometry. Unlike gE-gI, which binds Fc{gamma} at the slightly basic pH of the extracellular milieu but not at the acidic pH of endosomes, the gp68/Fc{gamma} complex is stable at pH values from 5.6 to pH 8.1. These data indicate that the mechanistic details of Fc binding by HCMV gp68 differ from those of host Fc{gamma}Rs and from that of HSV-1 gE-gI, suggesting distinct functional and recognition properties

    A single base-pair change creates a Chi recombinational hotspot in bacteriophage lambda.

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    Spin susceptibility of the superfluid 3^{3}He-B in aerogel

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    The temperature dependence of paramagnetic susceptibility of the superfluid ^{3}He-B in aerogel is found. Calculations have been performed for an arbitrary phase shift of s-wave scattering in the framework of BCS weak coupling theory and the simplest model of aerogel as an aggregate of homogeneously distributed ordinary impurities. Both limiting cases of the Born and unitary scattering can be easily obtained from the general result. The existence of gapless superfluidity starting at the critical impurity concentration depending on the value of the scattering phase has been demonstrated. While larger than in the bulk liquid the calculated susceptibility of the B-phase in aerogel proves to be conspicuously smaller than that determined experimentally in the high pressure region.Comment: 10 pages, 4 figures, REVTe

    Universal Behaviour of the Superfluid Fraction and Tc of He-3 in 99.5% Open Aerogel

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    We have investigated the superfluid transition of He-3 in a 99.5% porosity silica aerogel. This very dilute sample shows behaviour intermediary between bulk He-3 and He-3 confined to the denser aerogels previously studied. We present data on both the superfluid transition temperature and the superfluid density and compare our results with previous measurements. Finally, we show that the suppression of the superfluid transition temperature and suppression of the superfluid density of He-3 in aerogel follow a universal relation for a range of aerogel samples.Comment: 4 pages, 5 figures; 1 new figure, minor change

    Physical Electronics

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    Contains reports on three research projects

    Model of Inhomogeneous Impurity Distribution in Fermi Superfluids

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    The standard treatment of impurities in metals assumes a homogeneous distribution of impurities. In this paper we study distributions that are inhomogeneous. We discuss in detail the "isotropic inhomogeneous scattering model" which takes into account the spatially varying scattering on the scale of the superfluid coherence length. On a large scale the model reduces to a homogeneous medium with renormalized parameter values. We apply the model to superfluid 3He, where porous aerogel acts as the impurity. We calculate the transition temperature Tc, the order parameter, and the superfluid density. Both A- and B-like phases are considered. Two different types of behavior are identified for the temperature dependence of the order parameter. We compare the calculations with experiments on 3He in aerogel. We find that most of the differences between experiments and the homogeneous theory can be explained by the inhomogeneous model. All our calculations are based on the quasiclassical theory of Fermi liquids. The parameters of this theory for superfluid 3He in aerogel are discussed.Comment: 14 pages, 9 figures, minor change

    Mid-IR Spectroscopy of the Jovian Stratosphere perturbed by comet P/Shoemaker-Levy 9 Impact

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    The objective was to obtain spectra from 5 to 14 micron before, during, and after the impacts. We were awarded 2 flights of the KAO which was based in Melbourne, Australia for the events. Impacts R and W were covered, and the observations were completely successful. A paper reporting the observation of water vapor is in press, and other work is in progress as limited funding permits. The text of this report is adapted from that of the Icarus paper
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