59 research outputs found
Pepsinogen C: A Possible Biological Marker of Epithelial Differentiation in Barrett's Esophagus
Intestinal Metaplasia at The Esophagogastric Junction in Japanese Patients Without Clinical Barrett's Esophagus
A Cost Analysis of Outpatient Care for Patients With Barrett's Esophagus in A Managed Care Setting
Length of Barrett's oesophagus: an important factor in the development of dysplasia and adenocarcinoma.
In a 15 year prospective study of endoscopic surveillance of columnar lined oesophagus, 102 patients with a mean follow up of 54 (12.5) months and total follow up of 462 years have been evaluated. Of all the sets of biopsies taken, 59 in 21 patients were found to exhibit dysplasia or carcinoma. Four male patients had carcinoma of the oesophagus, indicating a 30 times increased risk of development of adenocarcinoma in columnar lined oesophagus. The length of columnar lined oesophagus in subjects with dysplasia was significantly longer as compared with the whole group (p = 0.01) and when compared with the patients without dysplasia (p = 0.005). None of the patients with dysplasia had a columnar lined oesophagus of less than 8 cm. Length of columnar lined oesophagus therefore seems to be a significant risk factor in the development of dysplasia and subsequent carcinoma and intensive follow up of patients with columnar lined oesophagus greater than 8 cm in length is recommended
Results of photodynamic therapy for ablation of dysplasia and early cancer in Barrett's esophagus and effect of oral steroids on stricture formation
Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification
- …