COMPUTER AIDED RESTORATION TOOLS TO ASSIST THE CONSERVATION OF AN ANCIENT SCULPTURE. THE COLOSSAL STATUE OF ZEUS ENTHRONED

The research focuses on the contribution of the integrated application of Computer Aided Restoration digital procedures as a means to guide the integration measure of an artifact, innovating and implementing the traditional investigation methods. The aim of the study was to provide effective geometrical-formal investigation tools in the frame of the conservation work of Zeus enthroned from Soluntum, conserved in the Archaeological Museum \u201cA. Salinas\u201d of Palermo. The paper describes the workflow of the 3D acquisition and graphical modeling with non-invasive digitalization and high information density techniques to assist the conservation of the legs of the throne, especially the integration of the missing part. Thanks to the technique of the digital fabrication it has been reconstruct the two missing parts following the theoretical criteria as: recognisability, compatibility and retractability. This innovative application of 3D digital technologies have showed as the integrated use of the new technology can be a useful tools for improving the conservation of a work of art

The indigenous settlement of Monte Iato (western Sicily): an ethnoarchaeometric approach for outlining local Archaic ceramic productions

An ethnoarchaeometric approach has been followed to identify the textural and compositional characteristics of the ceramic pastes produced in ancient Iaitas/Ietas, an indigenous site located in western Sicily on Monte Iato, a few tens of kilometres from Palermo. This approach was primarily motivated by the lack of discovered Archaic kilns or production sites/workshops and the inability to identify reference groups. Raw clays were sampled in the territory of San Cipirello and San Giuseppe Iato (today\u2019s municipalities both sited on the northern slopes of Monte Iato), together with representative historic tiles and bricks locally produced until fairly recently. Grain-size analysis and experimental firings were performed on the clay samples. A significant number of archaeological ceramic samples (incised and painted indigenous pottery dating back to the seventh\u2013fifth centuries BCE) from stratigraphic excavations on Monte Iato, and hypothesized as local productions on a stylistic-morphological basis, was carefully selected for archaeometric analysis. This set of samples (90 in total, comprising raw clays, historic tiles/bricks and archaeological ceramics) underwent a combined chemical and mineralogical-petrographic analysis to identify any possible compositional matching. This approach enabled the identification of minero-petrographic and chemical markers pertinent to the indigenous Archaic pottery produced at Monte Iato, although no evidence of coeval ceramic kilns has been found so far. Local raw clay sources have been documented and some significant points of the cha\ueene op\ue9ratoire adopted in antiquity have been noted (clay mixing and tempering practices). Attesting Monte Iato as a centre of ceramic production and defining both the microscopic fabric and the average composition of local pastes open up new perspectives in the complex issue concerning the production and regional circulation of incised and painted indigenous ceramics in Archaic Sicily

La produzione di ceramica da mensa a Solunto: un esempio di continuit\ue0 tecnologica dall\u2bcet\ue0 arcaica a quella ellenistico-romana.

Solunto is one of the most important Phoenician-Punic colonies of north-western Sicily. Archaeometric researches carried out in the last years ascertained a local production of transport amphorae during Archaic and Classic age (7th-5th century B.C.) through mineralogical, petrographical and chemical analysis of ceramic samples, kiln refuses and local raw materials (clays and alluvial sands). In connection with these earliest works, the present paper was focused on some specific forms of fine-tempered table ware of Archaic age and/or Classic-Hellenistic age. This pottery has been recurrently brought to light in Solunto and it is furthermore suspected to be, at least to some extent, a local reproduction. Thus a representative number of samples corresponding in style and morphology to Greek-colonial productions were subjected to thin-section and chemical analysis. Simultaneously, the same analytical routine was applied to an Hellenistic black-gloss ware form (Campana A), the plate classified as Lamboglia 36, considering a number of samples coming from Solunto as well as from others close centers. In both the cases the comparative elaboration of petrographic and chemical data concerning the ceramic samples and local raw clays let us to distinguish between the products made in the Solunto\u2bcs kilns and the imports from Greece or the Greek colony of Himera or from the Gulf of Naples area (for the black-gloss ware samples). Therefore, a durability of the manufacture crosswise more than four centuries was demonstrated for the ceramic kilns which were working at Solunto, which were able to reproduce several fine ware forms testifying an high technological level

Plastic adjustments of biparental care behavior across embryonic development under elevated temperature in a marine ectotherm

Phenotypic plasticity in parental care investment allows organisms to promptly respond to rapid environmental changes by potentially benefiting offspring survival and thus parental fitness. To date, a knowledge gap exists on whether plasticity in parental care behaviors can mediate responses to climate change in marine ectotherms. Here, we assessed the plasticity of parental care investment under elevated temperatures in a gonochoric marine annelid with biparental care, Ophryotrocha labronica, and investigated its role in maintaining the reproductive success of this species in a warming ocean. We measured the time individuals spent carrying out parental care activities across three phases of embryonic development, as well as the hatching success of the offspring as a proxy for reproductive success, at control (24℃) and elevated (27℃) temperature conditions. Under elevated temperature, we observed: (a) a significant decrease in total parental care activity, underpinned by a decreased in male and simultaneous parental care activity, in the late stage of embryonic development; and (b) a reduction in hatching success that was however not significantly related to changes in parental care activity levels. These findings, along with the observed unaltered somatic growth of parents and decreased brood size, suggest that potential cost-benefit trade-offs between offspring survival (i.e., immediate fitness) and parents' somatic condition (i.e., longer-term fitness potential) may occur under ongoing ocean warming. Finally, our results suggest that plasticity in parental care behavior is a mechanism able to partially mitigate the negative effects of temperature-dependent impacts

Heterogeneity of neuroinflammatory responses in amyotrophic lateral sclerosis: A challenge or an opportunity?

Amyotrophic Lateral Sclerosis (ALS) is a complex pathology: (i) the neurodegeneration is chronic and progressive; it starts focally in specific central nervous system (CNS) areas and spreads to different districts; (ii) multiple cell types further than motor neurons (i.e., glial/immune system cells) are actively involved in the disease; (iii) both neurosupportive and neurotoxic neuroinflammatory responses were identified. Microglia cells (a key player of neuroinflammation in the CNS) attracted great interest as potential target cell population that could be modulated to counteract disease progression, at least in preclinical ALS models. However, the heterogeneous/multifaceted microglia cell responses occurring in different CNS districts during the disease represent a hurdle for clinical translation of single-drug therapies. To address this issue, over the past ten years, several studies attempted to dissect the complexity of microglia responses in ALS. In this review, we shall summarize these results highlighting how the heterogeneous signature displayed by ALS microglia reflects not only the extent of neuronal demise in different regions of the CNS, but also variable engagement in the attempts to cope with the neuronal damage. We shall discuss novel avenues opened by the advent of single-cell and spatial transcriptomics technologies, underlining the potential for discovery of novel therapeutic targets, as well as more specific diagnostic/prognostic not-invasive markers of neuroinflammation

Effect of age and asthma duration upon elastase and alpha1-antitrypsin levels in adult asthmatics

In asthmatic subjects an imbalance between elastase and alpha1-antitrypsin (alpha1-PI) exists. This study aims to evaluate whether ageing per se affects the levels of elastase. Both young and elderly asthmatics with comparable severity and duration of disease, as well as young and elderly healthy subjects, underwent an induced sputum procedure to measure levels of elastase and alpha1-PI. The percentage of sputum neutrophils and eosinophils was higher in young and elderly asthmatics than in young and elderly controls. The levels of both total and active elastase were significantly higher in young and elderly asthmatics than in young and elderly controls, and directly correlated with the percentage of neutrophils. In addition, in both young and elderly asthmatics the levels of total and active elastase were negatively correlated with forced expiratory volume in one second values, but positively correlated with the duration of the disease. This study indicates that ageing per se does not necessarily lead to a progressive elastase/alpha1-antitrypsin imbalance in asthma, and suggests that an important variable in the development of airway remodelling in both young and elderly asthmatics is represented by the duration of the disease

Identification of medium mass (A=60-80) ejectiles from 15 MeV/nucleon peripheral heavy-ion collisions with the MAGNEX large-acceptance spectrometer

An approach to identify medium-mass ejectiles from peripheral heavy-ion reactions in the energy region of 15 MeV/nucleon is developed for data obtained with a large acceptance magnetic spectrometer. This spectrometer is equipped with a focal plane multidetector, providing position, angle, energy loss and residual energy of the ions along with measurement of the time-of-flight. Ion trajectory reconstruction is performed at high order and ion mass is obtained with a resolution of better than 1/150. For the unambiguous particle identification however, the reconstruction of both the atomic number Z and the ionic charge q of the ions is critical and it is suggested, within this work, to be performed prior to mass identification. The new proposed method was successfully applied to MAGNEX spectrometer data, for identifying neutron-rich ejectiles related to multinucleon transfer generated in the 70Zn+ 64Ni collision at 15 MeV/nucleon. This approach opens up the possibility of employing heavy-ion reactions with medium-mass beams below the Fermi energy (i.e., in the region 15-25 MeV/nucleon) in conjunction with large acceptance ray tracing spectrometers, first, to study the mechanism(s) of nucleon transfer in these reactions and, second, to produce and study very neutron-rich or even new nuclides in previously unexplored regions of the nuclear landscape.Comment: 6 pages, 6figure