665 research outputs found
Ischemic volvulus of the transverse colon: A case report and review of literature
A 75-year old male presented to the emergency room with worsening abdominal pain and distension. Plain radiographs were suggestive of a large bowel obstruction due to volvulus. An attempt to detorse the volvulus and decompress the colon endoscopically failed, after which the patient was taken for an exploratory laparotomy. A transverse colon volvulus was found, and an extended right hemicolectomy and ileostomy was performed. We discuss the diagnosis and management of transverse colon volvulus and review the pertinent literature
Tapered Fluidized Beds and the Role of Fluidization in Mineral Emplacement
One of the most prominent features of fluidized beds is their ability to mix and segregate. This is of great importance for many industrial processes, but takes on a particular significance for mineral extraction where a small amount of valuable matter is mixed with a large amount of waste. In this study we consider the occurrence of diamonds in the volcanic rock called “kimberlite”. These are often emplaced (erupted and deposited) in large volcanic pipes commonly referred to as “diatremes” (length scale of the order of a kilometre) with a vent at the bottom through which the minerals were introduced along with other fragmental particulate matter and a gas flow. The purpose of this study is to gain an understanding of the processes that led to the dispersal of minerals before their emplacement to allow efficient extraction. The paper describes experimental observations of a tapered fluidized bed. The objective was to identify the physical behaviour of gas and particles; so, of particular interest are the extent to which fluidization takes place within the bed, and the arrangements of particles seen. Gas flow-rate, particle size, and degree of taper were all varied. These observations can be used to identify the structures and processes that can take place; it is then possible to understand field data in terms of the physics that led to the emplacement of material. This will be shown using new data taken from southern Africa. Scale-up of evidence is of obvious difficulty in this system and this is discussed in terms of the possible behaviour of the bubbles that have generated mixing of material before emplacement
'Reclaiming the criminal' : the role and training of prison officers in England, 1877-1914
This article examines the role and training of prison officers in England, between 1877 and 1914. It is concerned with the changing penal philosophies and practices of this period and how these were implemented in local prisons, and the duties of the prison officer. More broadly, this article argues that the role of the prison officer and their training (from 1896) reflect wider ambiguities in prison policy and practice during this period
The effect of national and constituency level expectations on tactical voting in the British general election of 2010
The 2010 elections in the United Kingdom provided voters with numerous and diverse opportunities to reason strategically. The Liberal Democrats (Lib Dems)-traditionally finishing a distant third in terms of seats in Parliament-vied with labour to be the principal competition to the Conservatives, who failed to win a majority of seats, creating a rare case of what the British call a hung parliament. These conditions varied across constituencies at the district level, and we exploit this variation to study the incidence of "tactical" voting. But the national outcome also presented strategic considerations for voters, and the conditions varied to some extent over the course of the campaign, giving voters interviewed at different times different sets of national considerations for tactical voting. This presents us with the opportunity to investigate how both local and national considerations may shape strategic reasoning among voters and relate to each other and to the final choices of voters on Election Day
M-theory Compactifications on Manifolds with G2 Structure
In this paper we study M-theory compactifications on manifolds of G2
structure. By computing the gravitino mass term in four dimensions we derive
the general form for the superpotential which appears in such compactifications
and show that beside the normal flux term there is a term which appears only
for non-minimal G2 structure. We further apply these results to
compactifications on manifolds with weak G2 holonomy and make a couple of
statements regarding the deformation space of such manifolds. Finally we show
that the superpotential derived from fermionic terms leads to the potential
that can be derived from the explicit compactification, thus strengthening the
conjectures we make about the space of deformations of manifolds with weak G2
holonomy.Comment: 34 pages. Minor changes: typos corrected, references added. Version
to appear in Class. Quantum Gra
Two formation channels of UCDs in Hickson Compact Groups
The formation of ultra-compact dwarf galaxies (UCDs) is believed to be
interaction driven, and UCDs are abundant in the cores of galaxy clusters,
environments that mark the end-point of galaxy evolution. Nothing is known
about the properties of UCDs in compact groups of galaxies, environments where
most of galaxy evolution and interaction is believed to occur and where UCDs in
intermediate state of evolution may be expected. The main goal of this study is
to detect and characterize, for the first time, the UCD population of compact
groups. For that, 2 groups in different evolutionary stages, HCG 22 and HCG 90,
were targeted with VLT/FORS2/MXU. We detect 16 and 5 objects belonging to HCG
22 and HCG 90, respectively, covering the magnitude range -10.0 > M_R > -11.5
mag. Their colours are consistent with old ages covering a broad range in
metallicities. Photometric mass estimates put 4 objects in HCG 90 and 9 in HCG
22 in the mass range of UCDs (>2x10^6 M_Sun) for an assumed age of 12 Gyr.
These UCDs are on average 2-3 times larger than typical Galactic GCs, covering
a range of 2 >~ r_h >~ 21 pc. The UCDs in HCG 22 are more concentrated around
the central galaxy than in HCG 90, at the 99% confidence level. They cover a
broad range in [alpha/Fe] abundances from sub- to super-solar. The spectra of 3
UCDs show tentative evidence for intermediate age stellar populations. We
calculate the specific frequency (S_N) of UCDs for both groups, finding that
HCG 22 has about three times higher S_N than HCG 90. The ensemble properties of
the detected UCDs supports 2 co-existing formation channels: a star cluster
origin and an origin as tidally stripped dwarf nuclei. Our results imply that
the UCDs detected in both groups do not, in their majority, originate from
relatively recent galaxy interactions. Most of the detected UCDs have likely
been brought into the group with their host galaxies.[abridged]Comment: Accepted for publication at A&A, 17 pages, 9 figures + 2 additional
figure
Estimation of ash injection in the atmosphere by basaltic volcanic plumes: the case of the Eyjafjallajökull 2010 eruption
During explosive eruptions, volcanic plumes inject ash into the atmosphere and may severely affect air traffic, as illustrated by the 2010 Eyjafjallajökull eruption. Quantitative estimates of ash injection can be deduced from the height reached by the volcanic plume on the basis of scaling laws inferred from models of powerful Plinian plumes. In less explosive basaltic eruptions, there is a partitioning of the magma influx between the atmospheric plume and an effusive lava flow on the ground. We link the height reached by the volcanic plume with the rate of ash injection in the atmosphere via a refined plume model that (1) includes a recently developed variable entrainment law and (2) accounts for mass partitioning between ground flow and plume. We compute the time evolution of the rate of injection of ash into the atmosphere for the Eyjafjallajökull eruption on the basis of satellite thermal images and plume heights and use the dispersion model of the Volcanic Ash Advisory Center of Toulouse to translate these numbers into hazard maps. The classical Plinian model would have overestimated ash injection by about 20% relative to the refined estimate, which does not jeopardize risk assessment. This small error was linked to effective fragmentation by intense interactions of magma with water derived from melting of ice and hence strong mass partitioning into the plume. For a less well fragmented basaltic dry eruption, the error may reach 1 order of magnitude and hence undermine the prediction of ash dispersion, which demonstrates the need to monitor both plume heights and ground flows during an explosive eruption
Structural Model of the Rev Regulatory Protein from Equine Infectious Anemia Virus
Rev is an essential regulatory protein in the equine infectious anemia virus (EIAV) and other lentiviruses, including HIV-1. It binds incompletely spliced viral mRNAs and shuttles them from the nucleus to the cytoplasm, a critical prerequisite for the production of viral structural proteins and genomic RNA. Despite its important role in production of infectious virus, the development of antiviral therapies directed against Rev has been hampered by the lack of an experimentally-determined structure of the full length protein. We have used a combined computational and biochemical approach to generate and evaluate a structural model of the Rev protein. The modeled EIAV Rev (ERev) structure includes a total of 6 helices, four of which form an anti-parallel four-helix bundle. The first helix contains the leucine-rich nuclear export signal (NES). An arginine-rich RNA binding motif, RRDRW, is located in a solvent-exposed loop region. An ERLE motif required for Rev activity is predicted to be buried in the core of modeled structure where it plays an essential role in stabilization of the Rev fold. This structural model is supported by existing genetic and functional data as well as by targeted mutagenesis of residues predicted to be essential for overall structural integrity. Our predicted structure should increase understanding of structure-function relationships in Rev and may provide a basis for the design of new therapies for lentiviral diseases
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