Leptocybe invasa (HYMENOPTERA: EULOPHIDAE) EM MUDAS DE EUCALIPTO NO ESTADO DE SANTA CATARINA, BRASIL

The blue gum chalcid, Leptocybe invasa Fisher & La Salle (Hymenoptera: Eulophidae), native from Australia, can severely damage eucalyptus (Myrtaceae) plants. This insect was found on Eucalyptus grandis seedlings in May 2015, in Treze de Maio municipality in Santa Catarina state, Brazil.A vespa-da-galha, Leptocybe invasa Fisher & La Salle (Hymenoptera: Eulophidae), originária da Austrália, pode danificar severamente plantas de eucalipto (Myrtaceae). Este inseto foi registrado em mudas de Eucalyptus grandis em maio de 2015 no município de Treze de Maio, Estado de Santa Catarina, Brasil

Perfil sociodemográfico e epidemiológico dos pacientes em assistência domiciliar que utilizam o software CareYes: estudo descritivo

Introduction: With the rapid advancement of technology and the growing demand for more accessible and personalized healthcare services, home care (AD) software has emerged as an innovative solution for providing healthcare in the comfort of patients' homes. Objective: To characterize the profile of users who use an application focused on home care, called CareYes. Methods: observational and descriptive study, carried out using secondary data obtained from the electronic medical records of patients over 18 years of age who used the home care software called Careyes. The variables collected were related to AD patients and related to HC rendered. Results: Data from 1732 patients were analyzed. The sociodemographic and epidemiological profile of the patients who use the system is composed mostly of elderly people, the predominant sex is female, retired, the main caregivers are the children, they have completed higher education, and they live in the southeast. In addition, the main pathologies that affect these users are Alzheimer's, Cerebrovascular Accident (CVA), Systemic Arterial Hypertension (SAH) and neoplasms. Conclusion: the study was able to generate a representative report of the analyzed collective, offering significant information for the understanding of the needs of HC patients who use software in their care.      Introdução: Com o rápido avanço da tecnologia e a crescente demanda por serviços de saúde mais acessíveis e personalizados, softwares de assistência domiciliar têm emergido como uma solução inovadora para a prestação de cuidados de saúde no conforto dos lares dos pacientes. Objetivo: Caracterizar o perfil sociodemográfico e epidemiológico dos usuários que utilizam um aplicativo voltado para o atendimento domiciliar, denominado CareYes. Material e Métodos: Estudo observacional e descritivo, realizado por meio de dados secundários obtidos da análise de 1732 prontuários eletrônicos retirados do sistema, de pacientes acima de 18 anos, que utilizavam o software de assistência domiciliar chamado CareYes. As variáveis coletadas foram relacionadas aos pacientes em internação domiciliar, que são clientes das empresas que utilizam o CareYes. Resultados: Foram analisados dados de 1732 pacientes. O perfil sociodemográfico e epidemiológico dos pacientes que utilizam o sistema é composto, majoritariamente, por pessoas idosas, do sexo feminino, com ensino superior completo, residentes da região sudeste, aposentados e cujos principais cuidadores são os filhos. Além disso, as principais patologias que acometem esses usuários são Alzheimer, acidente vascular encefálico, hipertensão arterial sistêmica e neoplasias. Conclusão: O estudo foi capaz de gerar um relatório representativo do coletivo analisado, oferecendo informações significativas sobre o perfil epidemiológico e sociodemográfico dos pacientes, que contribui diretamente para a identificação e entendimento das necessidades de pacientes assistidos em assistência domiciliar que utilizam um software em sua assistência

CLASSES DE SOLOS NAS BACIAS HIDROGRÁFICAS DOS RIOS CAIABI E RENATO, AFLUENTES DO RIO TELES PIRES, NO SUL DA AMAZÔNIA

Em função dos avanços dos sistemas de produção agropecuária e da crescente demanda por alimentos no mundo, ainda é proeminente, a necessidade de se investigar as relações existentes entre os atributos do solo e as diferentes condições ambientais em que estão inseridos. Existem diversos produtos científicos que apresentam as caracterizações dos solos brasileiros, contudo, dependendo da aplicação, as maiores limitações estão vinculadas à escalas espaciais e amostragens em regiões isoladas. Neste trabalho é apresentada a classificação dos solos de dezoito perfis, distribuídos em duas bacias hidrográficas (rios Caiabi e Renato) afluentes do rio Teles Pires, no norte de Mato Grosso. Foi realizado o trabalho de campo, com descrição geral e morfológica dos horizontes e coleta de amostras deformadas e indeformadas para análises físicas e químicas em laboratório. A classificação dos 18 perfis de solos em campo foi realizada até o quarto nível categórico. A compatibilidade dos solos classificados em campo com dados disponibilizados pelo IBGE foi de 95% na ordem, 38% na subordem, 95% nos grandes grupos e 88% nos subgrupos.  A classe de solo predominante nas duas bacias hidrográficas é dos Latossolos, variando do vermelho a vermelho-amarelo, com matizes de 2,5 YR a 10,0 YR, todos distróficos. Foram observados horizontes plínticos, em posição diagnóstica na bacia do rio Renato e em posições não diagnósticas na bacia do rio Caiabi. Palavras-chave: recursos naturais; Latossolos; pedologia; fronteira agrícola; ecótono Cerrado-Amazônia.   Soil classes in the Caiabi and Renato river basins, tributaries of the Teles Pires river, in the south of the Amazon   ABSTRACT: Due to advances in agricultural production systems and the growing demand for food in the world, the need to investigate the relationships between soil attributes and the different environmental conditions in which they are inserted is still prominent. There are several scientific products that present the characterizations of Brazilian soils, however, depending on the application, the greatest limitations are linked to spatial scales and sampling in isolated regions. In this work, eighteen soil profiles were classified, distributed in two hydrographic basins (Renato and Caiabi rivers), of tributaries of the Teles Pires river, in the southern region of the Amazon. Field work was carried out with the general and morphological description of the horizons and the collection of deformed and undisturbed samples for further physical and chemical analysis in the laboratory. The classification of the 18 soil profiles in the field was compared up to the fourth categorical level with the IBGE data, 2021. The compatibility of the soils classified in the field with the IBGE data was 95% in the order, 38% in the suborder, 95% in the large groups and 88% in subgroups. The predominant soil class in the two hydrographic basins is Oxisol (Latosols), ranging from red to red-yellow, with hues from 2.5 YR to 10.0 YR, all dystrophic. Plinthic horizons were observed in diagnostic positions in the Renato river basin and in non-diagnostic positions in the Caiabi river basin. Palavras-chave: natural resource; Oxisol; pedology; agricultural frontier; Cerrado-Amazon ecotone

Validation Of The Ebmt Risk Score In Chronic Myeloid Leukemia In Brazil And Allogeneic Transplant Outcome.

The management of chronic myeloid leukemia (CML) has changed radically since the introduction of imatinib therapy. The decision of whether to offer a patient a hematopoietic stem cell transplant (HSCT) must be based on the probability of success of the procedure. The aim of this retrospective analysis of 1,084 CML patients who received an allogeneic HSCT in 10 Brazilian Centers between February 1983 and March 2003 was to validate the EBMT risk score. The study population comprised 647 (60%) males and 437 (40%) females, with a median age of 32 years old (range 1 - 59); 898 (83%) were in chronic phase, 146 (13%) were in accelerated phase and 40 (4%) were in blast crisis; 151 (14%) were younger than 20 years old, 620 (57%) were between 20 and 40 and 313 (29%) were older than 40; 1,025 (94%) received an HLA fully matched sibling transplant and only 59 (6%) received an unrelated transplant. In 283 cases (26%) a male recipient received a graft from a female donor. The interval from diagnosis to transplantation was less than 12 months in 223 (21%) cases and greater in 861 (79%). The overall survival, disease-free survival, transplant-related mortality and relapse incidence were 49%, 50%, 45% and 25%, respectively. Of the 1084 patients, 179 (17%) had a risk score of 0 or 1, 397 (37%) had a score of 2, 345 (32%) had a score of 3, 135 (12%) had a score of 4 and 28 (2%) a score of 5 or 6. The overall survival (OS) rate in patients with risk scores 0-1 and 2 was similar (58% and 55%, respectively) but significantly better than that in patients with scores 3 or more (score 3 - 44%, 4 - 36 % and 5-6 - 27%, respectively) pp<0.001). Disease-free survival (DFS) and transplant related mortality (TRM) in a patients with a score of 3 or more were 46% and 49%, respectively and the relapse rate beyond score 5-6 was 77%. Disease status had a negative impact on all outcomes (OS, DFS, TRM, and relapse). The OS rate for male recipients of a graft from a female donor was 40% compared to 52% among the other donor-recipient pairs (p=0.004). DFS and TRM were significant for disease phase and female donor-male recipient (p<0.001 and p<0.003, respectively). In our experience, age and interval between diagnosis and transplant did influence OS, DFS, TRM, and relapse rate. Our results validate the EBMT risk score in the context of a developing country and confirm its usefulness for making point decisions in the imatinib era.90232-

ANÁLISE DO PERFIL EPIDEMIOLÓGICO DE PACIENTES INTERNADOS POR DOENÇA RENAL CRÔNICA NO ESPÍRITO SANTO ENTRE 2019 A 2023

Chronic kidney disease is considered a public health problem worldwide. In Brazil, the incidence and prevalence of kidney failure are increasing; the prognosis is still poor and the costs of treating the disease are extremely high. This disease is multifactorial and often presents with a variety of laboratory alterations and its interpretation goes beyond the simple assessment of serum creatinine and urea concentrations. Regardless of the etiology of the underlying disease, the main outcomes in patients with CKD are its complications, resulting from renal functional loss, death and loss of renal function. Therefore, early diagnosis and appropriate management is essential, so that healthy lifestyle habits can be implemented as non-drug treatment and, if necessary, adherence to drug treatment. Thus, despite appearing simple, most patients find it difficult to adhere to treatment, which leads to a worsening of their chronic kidney disease. The aim of this study is to describe the epidemiological profile of patients hospitalized for chronic kidney disease in Espírito Santo between 2019 and 2023.A doença renal crônica é considerada problema de saúde pública em todo o mundo. No Brasil, a incidência e a prevalência de falência de função renal estão aumentando; o prognóstico ainda é ruim e os custos do tratamento da doença são altíssimos. Essa doença é multifatorial apresentando inúmeras vezes com alterações laboratoriais diversas e sua interpretação ultrapassa a simples avaliação das concentrações séricas de creatinina e uréia. Independentemente da etiologia da doença de base, os principais desfechos em pacientes com DRC são as suas complicações, decorrentes da perda funcional renal, óbito e&nbsp; perda de função renal. Assim, o diagnóstico precoce e manejo adequado é imprescindível, a fim de que se possa implementar hábitos de vida saudáveis como tratamento não-medicamentoso e, se necessário a adesão ao tratamento medicamentoso. Dessa forma, apesar de parecer simples, a aderência da maioria dos pacientes ao tratamento é difícil, o que ocasiona a piora do quadro da doença renal crônica. Assim, o objetivo do presente estudo é descrever o perfil epidemiológico dos pacientes internados por doença renal crônica no Espírito Santo entre os anos de 2019 a 2023

Cytokine profile associated with chronic and acute human schistosomiasis mansoni

The production and regulation of interleukin (IL) IL-13, IL-4 and interferon-gamma (IFN-³) was evaluated in 43 schistosomiasis patients with different clinical forms. Whole-blood cultures cytokine production in response to soluble egg antigen (SEA), soluble worm adult preparation (SWAP), mitogens, neutralizing antibodies or recombinant IL-13 were measured by ELISA. After SWAP stimulation, chronic patients, particularly hepatointestinals, produced higher levels of IL-4 in comparison with acute patients, suggesting the presence of a type 2 cytokine profile in these patients. Following SEA and SWAP stimulation, hepatosplenic (HS) patients showed increased levels of IFN-³ when compared with acute patients, indicating that HS disease in humans is associated with a type 1 cytokine response. The mechanisms of immune regulation are apparently different between the clinical stages of the disease, some of which are antigen-specific

Uma Reflexão sobre Didática na Educação Básica: o apostilamento no 4.º ano

Este trabalho descreve como a l&#243;gica adultoc&#234;ntrica, que h&#225; muito rege as rela&#231;&#245;es escolares, pode comprometer a did&#225;tica e suas metodologias, em especial o apostilamento. O aporte te&#243;rico se baseia no pragmatismo de Dewey e Peirce, fundamentando as an&#225;lises das linguagens que se interpenetram na elabora&#231;&#227;o dos conte&#250;dos. Abordam-se exerc&#237;cios de uma apostila do 4.&#186; ano do ensino fundamental, vendida em n&#237;vel nacional, relativos &#224;s disciplinas de geografia e matem&#225;tica. As asser&#231;&#245;es obtidas revelam que a experi&#234;ncia infantil foi pouco considerada, o que explica em parte o desinteresse das crian&#231;as pelos discursos pedag&#243;gico-cient&#237;ficos, tais como aparecem nas apostilas. Como resposta poss&#237;vel ao problema, prop&#245;e-se o encontro entre as subjetividades docente e discente

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio