L’intoxication Par Les Cremes Eclaircissantes Au Maroc Profil Epidemiologique

Objectives: In Morocco the large number of cosmetic products is sold freely without control or registration. The lack of knowledge of the composition of these products make therapeutic management in case of poisoning very difficult and sometimes causes unnecessary health spending even if these poisoning are often benign. The objective of this study is to establish the epidemiological profile of a poisoning by lightening creams collected at the Moroccan Poison Control and Pharmacovigilance Center. Methods: This is a retrospective study of poisoning case by lightening creams collected at the Moroccan Poison Control and Pharmacovigilance Center between 1992 and 2008. Results: During the study period, 95 cases were collected. The mean age is 20 years ± 1.4 [1-70 ans], and the F/M sex ratio is 1.73. In 90 (95%) cases, the route of poisoning was oral. The Suicide attempts represent 33 % of cases. Women are often voluntarily intoxicated. However, men were concerned by involuntary intoxication (p = 0.003). Eighty three cases were urban (87%) and 90 cases occured at home (95%). The digestive disorders were found in 68 cases associeted or not with a neurological disorders (33 cases), cardiovascular disorders (14 cases), and respiratory distress (6 cases). The evolution was favorable in all cases. Conclusions: The implementation of the new law recording to the registration of cosmetic products in the ministry of health before marketing will ensure certainly a better orientation of the poisoning case management and improve the patient safety

Cartography of Suicide-Related Health Indicators and Suicide Attempts in Morocco

The present work consists of a retrospective study of suicidal intoxication during a period stretching from January 1980 to December 2013, reported to the Poison Control and Pharmaco-vigilance Center of Morocco through two systems of data collection: Toxicological Information and Toxico-vigilance. The objective is to determine the spatio-temporal evolution of the incidence, lethality and mortality related to suicides and suicide attempts through intoxication in Morocco. During the study period, the average annual number of suicidal intoxications was 707 cases. All regions of Morocco have been affected but at variable rates. The average age of the victims is 24.39 ± 0.08 years, with a sex ratio of 2.41 in favor of the female sex. In the space of 34 years, the incidence is 2.4 per 100,000 inhabitants, the mortality is 0.67 per million inhabitants and the lethality is 0.08%. The annual increase in biological indicators makes suicides and suicide attempts a public health problem, through hospital care and the resulting socio-economic and psychological consequences. This problem seems much more common in urban areas and particularly in the big cities of Morocco

MODELING OF ACTIONS TO TAKE AFTER A SCORPION STING AND DEVELOPING A WEB BASED INFORMATION SYSTEM TO TRACK THE DIFFERENT INDICATORS SYSTEMATICALLY

To take the quickest and the correct decision when a scorpion stingsis decisive in terms of patient rescue. Based on a long experience andcollected information about envenomation, Anti Poison andPharmacovigilance Center of Morocco (CAPM) developed a guideline withclear actions to help the patients.European Scientific Journal April 2014 edition vol.10, No.12 ISSN: 1857 – 7881 (Print) e - ISSN 1857- 7431118The application of information technology in health sector has grownexponentially over the last years. This research aimed to model a health caresystem and make it easier to use by the health professionals. It will allow theclinician to monitor the evolution of the different vital signs and eventuallysuggest the best hospitalization (type of drug, reanimation, release...). Themain objective is to improve effectiveness and efficiency.The developed application contains sensible data, therefore the generalconcept is constructed to be secure. Furthermore, it is web oriented, in orderto facilitate the communication between the various sanitaire structures. Theprogram helps enormously to gather important statistics and analysis

Estimation De L’exhaustivité De La Surveillance Des Intoxications Médicamenteuses Dans La Région De Tanger-Tétouan-Al Hoceima, Maroc, 2014-2016

The aim of this study is to estimate the completeness of drug poisoning surveillance in the region of Tanger-Tétouan-Al Hoceima in Morocco. The study deals with cases of drug poisoning identified by the Moroccan Anti Poison Control Center (MPCC) and the cases collected by the registers of the provincial hospitals of the studied region between 2014 and 2016 period. The completeness of the surveillance was studied by the capture-recapture method. During the study period, 835 cases of drug poisoning were identified by the MPCC and 892 cases from the registers of hospitals in the region. The number of duplicates was 78. The capture-recapture method made it possible to estimate the total number of cases at 9 549 (95% CI: 8,199-10,900). The completeness of surveillance is estimated at 8.74% from MPCC and 9.34% from hospital registers in the region. The capture-recapture method provided limited completeness of monitoring for drug poisoning in the study area. Improved awareness of doctors about the declaration is necessary to strengthen the system of surveillance of poisoning in Morocco

Profil Épidémiologique Des Avortements Provoqués Au Maroc (1992/2014)

On the set of the poisonings brought together in the the Moroccan Anti Poison Control Center (MPCC) for a period spread on 22ans (1992/2014), 169 cases of abortion caused by poisoning were recorded. The objective of this work is to describe the epidemiological characteristics and to determine the specific lethality of abortions caused in Morocco between 1992 and 2014 by basing itself on a retrospective study of the cases of abortions. During this period 169 cases of abortion caused by poisoning were declared to the MPCC by means of telephone and mail, the region which knew the maximum of the cases is Rabat Salé Zemmour Zair, the environment rural prevail the risks of abortion with 90 %, the average age was 28,09±11,81, the evolution is generally positive

Les Effets Indésirables Digestifs De La Chimiothérapie : Cas Des Patients De L’institut National D’oncologie De Rabat (Maroc)

An adverse reaction of an anticancer drug is a harmful and an unintended reaction by patient suffering from cancer disease who is often polymedicated. The treatment of cancers by anti-cancer molecules produces serious adverse drug effects. The main purpose of this paper is to present and evaluate the digestive adverse effects involved in anti-cancer drugs and their potential of correlation to anticipate, prevent and improve the quality of care of patient suffering from cancer disease. This is a prospective study that that enrolled 147 patients seen between January 25 and June 25, 2009 with adverse drug reactions due to an anticancer treatment. Breast and cavum cancers present 34% of cases. The average age was 46.52 years. The sex ratio (M / F) was 0.33. During the study period 283 Adverse drug effects of anticancer drugs were collected with a predominance (132) adverse digestive effects and 32 anticancer drugs were counted on all medical prescriptions. Nausea and vomiting are the most common side effects, sometimes very severe. The availability of anti-emetics in the family of 5-HT3 serotoninergic antagonists has considerably improved the experience of patients undergoing anticancer chemotherapy, hence the importance of pharmacovigilance as a tool is to improve the quality of anticancer care

Geographical distribution of health indicators related to snake bites and envenomation in Morocco between 1999 and 2013

OBJECTIVES Envenomation from snake bites is a significant cause of morbidity and mortality worldwide. The aim of this study was to describe the epidemiological features of snake bites in Morocco and to evaluate time-space trends in snake bite incidence, the mortality rate, and the case-fatality rate. METHODS This is a retrospective study of snake bite cases reported to the Moroccan Poison Control Center between 1999 and 2013. RESULTS During the study period, 2,053 people were bitten by snakes in Morocco. Most victims were adults (55.4%). The average age of the patients was 26.48±17.25 years. More than half of the cases (58.1%) were males. Approximately 75% of snake bites happened in rural areas, and 85 deaths were recorded during this period. The incidence of snake bites remained generally steady over the 15-year period of this study, with a marked increase noted since 2012. The mortality rate has increased slightly, from 0.02 deaths per 100,000 inhabitants in 1999 to 0.05 in 2013. The geographical distribution of snake bite cases in the regions of Morocco showed that Tanger-Tétouan had the highest annual incidence of snake bites (1.41 bites per 100,000 inhabitants). However, the highest annual mortality rates were recorded in the Guelmim-Es Semara and Souss-Massa-Drâa regions (0.09 deaths per 100,000 inhabitants for both regions). CONCLUSIONS The geographical distribution of the incidence, mortality, and case-fatality rates of snake bites in Morocco showed large disparities across regions during the three 5-year periods included in this study, meaning that certain areas can be considered high-risk for snake bites

INTOXICATION PAR LE PEROXYDED’ HYDROGENE DESTINE A LA DECOLORATION DE CHEVEUX: DONNEES DU CENTRE ANTIPOISON ET DE PHARMACOVIGILANCE DU MAROC

To assess the extent and severity of poisoning by hydrogen peroxide dye hair used as the Moroccan population, a retrospective epidemiological study of all cases of poisoning reported, collected by the Moroccan poison control and pharmacovigilance center, between 1987 and 2011 was realized. The center has received 43 reports. The mean age was 18 ± 2 years [0.1-50 years] and the female / male ratio was 2. The majority of cases of poisoning were occurred in th urban area (35 cases) and at home (31 cas). The digestive disorders were found in 17 cases, associeted or not with a neurological disorders (2 cases), cardiovascular disorders (1 case) and skin disorders e (1 case).Twenty patients were referred to the emergency care unit). A symptomatic treatment was ordered in 26 cases and gastrointestinal descontamination in 11 cases. The evolution was favorable in all cases

CARACTÉRISTIQUES SOCIO-ÉPIDÉMIOLOGIQUES ET ÉVOLUTIVES DES INTOXICATIONS AIGUËS AU MAROC : CAS DE LA RÉGION DE L’ORIENTAL

A retrospective epidemiological study concerning 4 098 cases of acute poisoning registered in the region of the Oriental between January, 2007 and December, 2011 was realized. The data have been collected by The Moroccan Poison Control and Drug Monitoring Center (centre anti-poison et de pharmacovigilance "CAPM"). Such study aims to reduce morbidity and mortality resulting from poisoning in the oriental region, through the description of the major epidemiological characteristics associated with it. The results showed the average age of the intoxicated 24.7±16.4 years. The poisonings in this region concerned mainly the adults whose age is understood between 20 years and 74 years (56.9 %). The lethality rate was more important at the elderly Person ([> 75]) (2.62 %). The female prevailed with (62.8%), the sex ratio (F/M) being 1.68. The frequencies of the highest poisonings were recorded in the urban middle with 90.1 %. The poisonings were accidental in 76.6 % of the cases. The clinical state of the patients was for the greater part symptomatic (74.9 %). The most incriminated products were drugs with 29.6 % of the cases. Among 3 453 patients for whom the evolution was known, 3 407 cases had favorably evolved, 46 had died, that is a lethality of 1.3 %. The study of the effect of the studied parameters on the evolution of the health status of patients has led to progress as follows: The origin (urban, rural) and the clinical state (symptomatic, asymptomatic) presented a significant association with the evolution of the patients: The Odds ratio was respectively, (OR=2.33, p=0.028) and (OR=6.51, p=0.001). To reduce the incidence of acute accidental and intentional poisonings, prevention and improvement of socio-economic conditions remain the treatment of choice

CARACTERISTIQUES EPIDEMIOLOGIQUES ET CLINIQUES DES ENVENIMATIONS PAR LES INSECTES HYMENOPTERES AU MAROC EPIDEMIOLOGICAL AND CLINICAL CHARACTERISTICS OF THE ENVENOMATIONS CAUSED BY HYMENOPTERA INSECTS IN MOROCCO

In order to reduce the morbidity of envenomations caused by Hymenoptera insects in Morocco, this study evaluates the incidence of those cases in the regions that have been affected by this type of poisoning and describes the epidemiological and clinical characteristics of the poisoned patients. A descriptive retrospective analysis was conducted on 175 cases of envenomation. Data was collected from two sources, the Toxico-monotoring systems and toxicological information, both based on suspected or proven data from The Moroccan Poison Control and Drug Monitoring Center (CAPM) from the 1 January 2008 to 31 December 2011. Entry and statistical analysis were done using Epi Info 2002. According to the results, the region of Tangier-Tetouan has recorded the highest number of poisoned patients (67 cases) with an incidence of 0.0062 per 100 000 inhabitants. The average age of the poisoned population was 21,6±16,9. Male patients were the most affected with 66% of cases (sex ratio (M / F) = 2). Hymenoptera insect bites have occurred most often in urban areas (62% of cases). There was a peak in bites during July, which corresponds to the period of the proliferation of insects (bees-ants...). 75.4% of patients were symptomatic. The most frequent clinical signs were local edema (25.9%), pruritus (20.5%) and localized pain (18.3%). The evolution was favorable in 81% of cases, 2 cases (1%) with had ongoing sequels and no cases of death were recorded. By studying these 175 cases of envenomation caused by Hymenoptera, we offers education and information to the Moroccan population, and an ecological knowledge about hymenopteran species involved, and the proper management of the poisoned for a better outcome