7 research outputs found
Successful Packing of Hepatic Hematoma Rupture Following Preeclampsia: A Case Report (Running title: Hepatic Hematoma and Preeclampsia)
Seroepidemiology of toxoplasmosis and its risk factors in newly married women of Jovin city (Razavi Khorasan) in 1400
Comparison of vaginal misoprostol, laminaria, and isosorbide dinitrate on cervical preparation and labor duration of term parturient: a randomized double-blind clinical trial
Background: Cervical ripening plays an important role in successful labor induction.
Objective: This study aimed to compare the effects of misoprostol, laminaria tent, and isosorbide dinitrate
(ISDN) on cervical ripening.
Methods: This double-blind three-armed clinical trial was conducted at Shahidan Mombini Teaching Hospital in
Sabzevar, Iran, in 2016 on 96 singleton term pregnant women. Participants were randomly allocated to receive
either two 20-mg ISDN tablets vaginally every 4 hours for a maximum of three doses or 25 mcg misoprostol
vaginally every 6 hours for a maximum of two doses or laminaria tent for a maximum of 12 hours. The method of
randomization was covariate adaptive randomization and the primary outcome measures were Bishop Score
changes and labor duration. SPSS software version 18 was used for statistical analyses. Kruskal-Wallis, chi- square and ANOVA tests were applied for data analyses.
Results: Bishop Score changes were higher in the misoprostol group than in the two other groups (p=0.014).
Time from start of medication to active phase of labor and delivery were 6.22±3.11 and 11.78±5.3 minutes in the
misoprostol group, 11.25±3.07 and 17.62±4.07 minutes in the laminaria group, and 10.12±3.48 and 17.37±4.79
minutes in the ISDN group respectively (p<0.001). Cesarean rate was higher in the misoprostol group than the
two other groups (p=0.016). No significant differences were observed between the study groups in terms of
Apgar score and meconium-stained amniotic fluid.
Conclusions: Use of misoprostol results in more improvement of Bishop Score and reduced length of labor
phases in comparison to laminaria tent and ISDN.
Trial registration: The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the
Irct ID: IRCT2016050527643N2 in the Iranian Registry of Clinical Trials IRCT2015040921670N1.
Funding: The authors received no financial support for the research, authorship, and/or publication of this article
Assessment of Prevalence of Asymptomatic Bacteriuria and Antibiotic susceptibility and its Risk factors in pregnant women living in Sabzevar City from 2014 to 2015
Introduction: Asymptomatic bacteriuria is a common problem during pregnancy. Delayed diagnosis and treatment may end up in harmful events for both mother and fetus. Physiological changes of urinary system during pregnancy facilitate the growth of microorganisms and cause this infection. This study was performed with aim to evaluate the prevalence of asymptomatic bacteriuria and determine the antibiotic susceptibility and its risk factors in pregnant women. Methods: This cross-sectional study was performed on 220 pregnant women referred to Shahidan Mobini Hospital in Sabzevar in 2014-2015. Sterile urine sample of pregnant women was analyzed in terms of Full urine test and culture. Antibiogram of isolated bacteria was done with colony count greater than 100000 by Bauer-Kirby Disk Diffusion. Individual characteristics of the subjects were recorded in the checklist. Data were analyzed by SPSS software (version 19) and Chi-square test. P0.05). Most common isolated organisms were Escherichia coli and staphylococcus ureus. Antibiogram results showed that cotrimoxasol, nitroforantoin, ciproflouxasin and nalidixic acide are appropriate antibiotics for treatment of patients. Conclusion: Asymptomatic bacteriuria has favorable prevalence in Sabzevar city. In the screening of this situation, considering individual and social characteristics seems to be necessary