40 research outputs found

    The Design Technique for Power Management Unit of the Tag IC for Radio Frequency Identification of Critical Infrastructure Objects

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    The ultra-high frequency (UHF) tag IC’s main part of the power management unit (PMU) design technique is presented. The technique is a step-by-step algorithm for designing a PMU and consists of five interrelated stages. At the first stage, the requirements for the parameters of the PMU (output voltage, output DC power, efficiency, output capacitor capacity) and the Q-factor of the tag analog front-end are determinates. At the second stage, the design of an electrical circuit of a voltage multiplier (VM) is carried out. VM is required to convert the voltage of the input radio frequency (RF) signal into an DC voltage. During the third stage, the design of the electrical circuit of the DC voltage limiter is carried out, which is necessary to reduce the output voltage of VM to a safe level. The result of stage 4 is an electrical circuit of surge protection designed to provide the required level of immunity of the tag IC to the effects of electrostatic discharge and a high-power RF signal. As part of the final stage, the evaluation and alignment with the required Q-factor value of the tag IC analog front-end is carried out. The proposed technique can be used for the development of domestic UHF tag ICs (ISO 18000-6C, GJB 7377.1, etc.) based on CMOS technological processes, including ICs designed for radio frequency identification of critical infrastructure objects. Using the presented technique, the design of a PMU with an estimated efficiency value of 70%, an estimated Q-factor of the analog front-end of less than 15 at an RF input signal power of -12.7 dBm was performed

    A new design for a green calcium indicator with a smaller size and a reduced number of calcium-binding sites

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    Genetically encoded calcium indicators (GECIs) are mainly represented by two- or one-fluorophore-based sensors. One type of two-fluorophore-based sensor, carrying Opsanus troponin C (TnC) as the Ca2+-binding moiety, has two binding sites for calcium ions, providing a linear response to calcium ions. One-fluorophore-based sensors have four Ca2+-binding sites but are better suited for in vivo experiments. Herein, we describe a novel design for a one-fluorophore-based GECI with two Ca2+-binding sites. The engineered sensor, called NTnC, uses TnC as the Ca2+-binding moiety, inserted in the mNeonGreen fluorescent protein. Monomeric NTnC has higher brightness and pH-stability in vitro compared with the standard GECI GCaMP6s. In addition, NTnC shows an inverted fluorescence response to Ca2+. Using NTnC, we have visualized Ca2+ dynamics during spontaneous activity of neuronal cultures as confirmed by control NTnC and its mutant, in which the affinity to Ca2+ is eliminated. Using whole-cell patch clamp, we have demonstrated that NTnC dynamics in neurons are similar to those of GCaMP6s and allow robust detection of single action potentials. Finally, we have used NTnC to visualize Ca2+ neuronal activity in vivo in the V1 cortical area in awake and freely moving mice using two-photon microscopy or an nVista miniaturized microscope

    Angiography imaging of giant extracranial internal carotid aneurysm

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    Giant extracranial aneurysms of internal carotid artery are rare anatomical anomalies of magistral vessels. We report about 64-year female with giant (32x39 mm) aneurysm. She refused operative treatment and was dischargedВ статье представлен случай ангиографического наблюдения гигантской (32х39 мм) аневризмы экстракраниального отдела внутренней сонной артерии у пациентки 64 лет. После проведения ангиографии пациентке было предложено оперативное лечение, от которого она отказалась. Случай интересен демонстрацией редкой сосудистой аномали

    Endovascular revascularisation of lower limbs in a patient with dextrocardia and polymorbidity

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    Dextrocardia and situs inversus totalis are rare anatomical anomalies. We report the case of a 54-year woman with critical chronic lower limb ischemia, successfully treated by percutaneous transluminal angioplasty.В статье приводится успешный случай эндоваскулярной реваскуляризации нижних конечностей у полиморбидной пациентки 54 лет с аномалиями расположения внутренних органов – декстрокардией и situs inversus totalis. Балонная ангиопластика под местной анестезией может являться методом выбора при наличии критической ишемии нижних конечностей и выраженной сопутствующей патологии, которая накладывает ограничения на анестезиологическое пособие

    Методика выделения стромально-васкулярной фракции из жировой ткани

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    The rapid development of regenerative medicine and cell biology is opening up new therapeutic options that will be available in the near future. Stem cells are of great interest due to their potential for tissue and organ repair. The article describes a protocol for the isolation of the stromal-vascular fraction by a mechanical method.Стремительное развитие регенеративной медицины и клеточной биологии открывает новые терапевтические возможности, которые будут доступны в ближайшем будущем. Стволовые клетки вызывают высокий интерес благодаря своему потенциалу к восстановлению тканей и органов. В статье описан протокол по выделению стромально-васкулярной фракции механическим методом

    Study of the relationship between mental tension and risk factors for developing cardiovascular diseases

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    conducted a study of the influence of mental stress on risk factors for developing cardiovascular diseases, which revealed a statistically significant tendency to worsen blood pressure, heart rate and blood glucose levels after 3-hour fasting with an increase in the level of mental stress in 3rd-year students. The largest part of the subjects with high levels of stress had a bad habit – Smoking.провели исследование влияния психической напряжённости на факторы риска развития сердечно-сосудистых заболеваний, которое выявило статистически достоверную тенденцию к ухудшению показателей артериального давления, частоты сердечных сокращений и уровня глюкозы в крови после 3-часового голодания при увеличении уровня психической напряженности у студентов 3 курса. Наибольшая часть обследуемых с высоким уровнем стресса имели вредную привычку – курение

    Исследование возможности регенерации иода из газовых потоков при иодидном рафинировании

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    The article considers the possibility of recovering elemental iodine vapor from the waste gas in the zirconium refining section Carbon sorbents of various types produced in Russia were used for the refining. The sorbents were tested in laboratory units and directly in the production area. The optimal sorbent kind was found. The characteristics of iodine recovery from saturated sorbents were determined. Recommendations on the filter design are givenРассмотрена возможность улавливания паров элементарного иода из отходящих газов участка рафинирования циркония угольными сорбентами различных типов российского производства. Испытания сорбентов проведены на лабораторных установках и непосредственно на производственном участке. Подобран оптимальный вид сорбента. Определены показатели извлечения иода из насыщенных сорбентов. Выданы рекомендации конструкции фильтра

    Mixed Graph Colouring as Scheduling a Partially Ordered Set of Interruptible Multi-Processor Tasks with Integer Due Dates

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    We investigate relationships between scheduling problems with the bottleneck objective functions (minimising makespan or maximal lateness) and problems of optimal colourings of the mixed graphs. The investigated scheduling problems have integer durations of the multi-processor tasks (operations), integer release dates and integer due dates of the given jobs. In the studied scheduling problems, it is required to find an optimal schedule for processing the partially ordered operations, given that operation interruptions are allowed and indicated subsets of the unit-time operations must be processed simultaneously. First, we show that the input data for any considered scheduling problem can be completely determined by the corresponding mixed graph. Second, we prove that solvable scheduling problems can be reduced to problems of finding optimal colourings of corresponding mixed graphs. Third, finding an optimal colouring of the mixed graph is equivalent to the considered scheduling problem determined by the same mixed graph. Finally, due to the proven equivalence of the considered optimisation problems, most of the results that were proven for the optimal colourings of mixed graphs generate similar results for considered scheduling problems, and vice versa
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