Soliton absorption spectroscopy

We analyze optical soliton propagation in the presence of weak absorption lines with much narrower linewidths as compared to the soliton spectrum width using the novel perturbation analysis technique based on an integral representation in the spectral domain. The stable soliton acquires spectral modulation that follows the associated index of refraction of the absorber. The model can be applied to ordinary soliton propagation and to an absorber inside a passively modelocked laser. In the latter case, a comparison with water vapor absorption in a femtosecond Cr:ZnSe laser yields a very good agreement with experiment. Compared to the conventional absorption measurement in a cell of the same length, the signal is increased by an order of magnitude. The obtained analytical expressions allow further improving of the sensitivity and spectroscopic accuracy making the soliton absorption spectroscopy a promising novel measurement technique.Comment: 9 pages, 7 figures

The Athletes\u27 Relationships with Training Scale (ART): A Self-Report Measure of Unhealthy Training Behaviors Associated with Eating Disorders

Objective: Several studies indicate that eating-disorder (ED) psychopathology is elevated in athletes compared to non-athletes. The assessment of excessive exercise among athletes is a challenge because, compared to non-athletes, athletes are required to train at higher intensities and for longer periods of time. However, individuals participating in competitive sports are still susceptible to unhealthy physical-activity patterns. Most ED assessments were developed and normed in non-athlete samples and, therefore, do not capture the nuances of athletes\u27 training experiences. The purpose of the current study was to develop and validate a clinically useful, self-report measure of unhealthy training behaviors and beliefs in athletes, the Athletes\u27 Relationships with Training Scale (ART). Method: The initial item pool was administered to N = 267 women collegiate athletes who were participating in an ED prevention program study and N = 65 women athletes who were in ED treatment. Results: Factor analyses indicated the ART had a four-factor structure. Factorial and construct validity of the ART were demonstrated. ART scores significantly predicted health care utilization and differed between athletes with an ED versus athletes without an ED. For athletes in ED treatment, ART scores significantly decreased from treatment admission to discharge. Discussion: The ART showed evidence of strong psychometric properties and clinical utility. The ART could be helpful for clinicians and athletic trainers to help gauge whether athletes are engaging in unhealthy training practices that may warrant clinical attention and for tracking clinical outcomes in athletes with EDs who are receiving treatment

Is sea-ice-driven Eurasian cooling too weak in models?

This is the author accepted manuscript. The final version is available from Nature Research via the DOI in this recordData availability: The FACTS and CESM simulations are freely available and were obtained from the following repositories: https://www.esrl.noaa.gov/psd/repository/facts and https://www.cesm.ucar.edu/projects/community-projects/LENS

The origin of intergalactic thermonuclear supernovae

The population synthesis method is used to study the possibility of explaining the appreciable fraction (20^+12_15%) of the intergalactic (no-host) type Ia supernovae observed in galaxy clusters (Gal-Yam ete al. 2003) by binary whote dwarf merginngs in the cores of globular clusters. In a typical globular cluster, the number of merging double white dwarfs is fount to be smaller than 10^{-13} per year per average cluster star during the entire evolution of the cluster, which is a factor of 3 higher than in a Milky-Way-type galaxy. From 5 to 30% of the merging white dwarfs are dynamically expelled from the cluster with barycenter velocities up to 150 km/s. SN Ia explosions during the mergers of binary white dwarfs in dense star clusters may account for \sim 1% of the total rate of SN Ia in the central parts of galaxy clusters if the baryon mass fraction in such star clusters is \sim 0.3%.Comment: 8 pages, 3 figs. Astronomy Letters (in press

Dynamics and Radiation of Young Type-Ia Supernova Remnants: Important Physical Processes

We examine and analyze the physical processes that should be taken into account when modeling young type-Ia SNRs, with ages of several hundred years. It is shown, that energy losses in the metal-rich ejecta can be essential for remnants already at this stage of evolution. The influence of electron thermal conduction and the rate of the energy exchange between electrons and ions on the temperature distribution and the X-radiation from such remnants is studied. The data for Tycho SNR from the XMM-Newton X-ray telescope have been employed for the comparison of calculations with observations.Comment: 19 pages, 8 figure

Dermatological care for oncopatients with skin toxicity

The aim of the study – study of the quality of life of patients with cancer treated with tyrosine kinase inhibitors.Цель исследования – изучение качества жизни пациентов с онкологическими заболеваниями, находящимися на терапии ингибиторами тирозинкиназы

Association of the AGT, ACE, NOS3 polymorphism with subclinical arterial wall changes and cardiovascular diseases risk factors

Background. Renin-Angiotensin-Aldosterone System activation (RAAS) and nitric oxide (NO) reduction lead to the changes in the arterial wall, which, in turn, create a favourable environment for the development of cardiovascular diseases (CVD). There is only limited knowledge of the influence of proteins participating in the RAAS activation and providing NO bioavailability on the parameters of the arterial wall state (pulse wave velocity (PWV), carotid artery intima-media thickness (cIMT), endothelium-dependent vasodilation (EDVD), presence of atherosclerotic plaques) and risk factors of CVD. Aim. Finding the association between the AGT, ACE, NOS3 polymorphism and PWV, cIMT, EDV, presence of atherosclerotic plaques and risk factors of CVD in healthy subjects. Methods. Using intergroup analysis and models of multiple logistic regression, we examined the association of AGT с.521СТ polymorphism, AСE InsDel polymorphism, NOS3 с.894GT polymorphism with arterial wall changes and risk factors of CVD in 160 healthy people of different ages. Results. The CT genotype of AGT с.521СТ polymorphism was associated with lower levels of systolic blood pressure (BP) (p=0.013) and central systolic BP (p=0.029), higher level of Insulin-Like Growth Factor (IGF) (p=0.027). The DD genotype of ACE InsDel polymorphism was associated with a higher waist/hip ratio (p=0.044), lower level of high density lipoprotein cholesterol (p=0.01), lower index of EDVD (p=0.042), higher incidence ofendothelial dysfunction (ED) (p=0.026). The GG genotype of NOS3 с.894GT polymorphism was associated with higher levels of central systolic BP (p=0.022) and central mean BP (p=0.033), total cholesterol (p=0.025), low density lipoprotein cholesterol (p=0.014) and IGF (p=0.042), higher incidence of ED (p=0.007), albuminuria (p=0.032) and insulin resistance (p=0.03). Conclusion. We have found the association of the AСE and NOS3 polymorphism with endothelial dysfunction and the metabolic status

Thermonuclear Burning Regimes and the Use of SNe Ia in Cosmology

The calculations of the light curves of thermonuclear supernovae are carried out by a method of multi-group radiation hydrodynamics. The effects of spectral lines and expansion opacity are taken into account. The predictions for UBVI fluxes are given. The values of rise time for B and V bands found in our calculations are in good agreement with the observed values. We explain why our results for the rise time have more solid physical justification than those obtained by other authors. It is shown that small variations in the chemical composition of the ejecta, produced in the explosions with different regimes of nuclear burning, can influence drastically the light curve decline in the B band and, to a lesser extent, in the V band. We argue that recent results on positive cosmological constant Lambda, found from the high redshift supernova observations, could be wrong in the case of possible variations of the preferred mode of nuclear burning in the earlier Universe.Comment: 20 pages, 5 figures, presented at the conference "Astronomy at the Eve of the New Century", Puschino, May 17-22, 1999. A few references and a table added, typos correcte

Frequency of strains with multiple antibiotic resistance in the structure of opportunitistic pathogens

Background. The problem of antibiotic resistance has remained significant for the medical community for more than half a century, since the first cases of resistance to penicillin were registered.   The aim. Analysis of the long-term dynamics of changes in the antibacterial resistance of microorganisms and the creation of a collection of multi-resistant strains of opportunistic microorganisms.   Materials and methods. The study included data from 3173 bacteriological samples of various loci of the human body for 2010 and 2020–2021. The sensitivity of isolated cultures was determined by the disk diffusion method to antimicrobial drugs of the following groups: penicillins, cephalosporins, fluoroquinolones, aminoglycosides, carbapenems, tetracyclines, macrolides, lincosamides, oxazolidinones, glycopeptides and others.   Results. In the general structure of conditionally pathogenic microorganisms, a significant increase in the frequency of isolation of multidrug-resistant representatives of the genus Staphylococcus by two or more times was observed in 2021 compared to 2010 and 2020. We also observed a significant increase in the proportion of multidrug-resistant Streptococcus spp. and non-fermenting gram-negative bacteria. These changes marked the beginning of the creation of a collection of conditionally pathogenic microorganisms with multiple antibacterial resistance. In the structure of multiresistant microorganisms included in the “Collection of human microbiota of the Irkutsk region”, the leading positions belong to Klebsiella pneumoniae (23.81 %), Escherichia coli (19.05 %) and Staphylococcus aureus (22.22 %).   Conclusion. Antibiotic resistance monitoring is an important measure to control the resistance of community-acquired and nosocomial (nosocomial) microorganisms both within a particular country and globally