Sample description.

a<p>Graduation level. M (mean); S.D. (standard deviation); N: number of patients.</p

Features of cognitive impairment in mastocytosis.

<p>In the ordinate axis each line represents a patient. In the abscissa axis the severity of the cognitive impairment is represented for each column (1: slight; 2: moderate; 3: severe). Columns displays features of cognitive impairment observed (A: auditory; V: visual; I: immediate; D: delayed; WM: working memory). Black marks gives the feature and the severity of cognitive impairment for each patient. Among the 22 patients WM impairment as the most frequent concerning 16 patients (10 with WM alone and 6 associated to auditory and/or visual impairment. In our sample (n = 57), 22 patients (38.6%) were diagnosed with cognitive impairment. 12 patients (59.1%) have slight impairment; 7 (27.3%) have moderate impairment and severe impairment affected 3 (13.6%) patients.</p

Cognitive impaired patients are no more depressed than patients without cognitive impairment.

<p>We performed an unpaired t-test to compare depression scores of patients with and without cognitive impairment. In the group of patients diagnosed with cognitive impairment mean depression score was 15.8 (SD = 9.09). In the group without cognitive impairment diagnosis the mean depression score was 12.48 (SD = 6.59).The analysis showed no significant difference between the groups (t = 1.296; p = 0.200). CI: cognitive impairment; ns: not significant.</p

Comparison of dimension scores between the case and control groups.

<p>Comparison of dimension scores between the case and control groups.</p

Cross-over schema and distribution of subjects.

<p>Cross-over schema and distribution of subjects.</p

Scatterplots of the progress of the students on each item of the questionnaire between the beginning and the end of the rotation.

<p>Plots are shown with one row for each chief resident, left column for the Control group, and right column for the Case group. Item scores have been normalized. A smoothed estimator is fitted for each subplot.</p

Drug order errors corrected by Chief Residents.

<p>Drug order errors corrected by Chief Residents.</p

Boxplots of the progress distribution on all questionnaire items for each (a) chief resident, (b) intervention group, (c) student.

<p>Boxplots of the progress distribution on all questionnaire items for each (a) chief resident, (b) intervention group, (c) student.</p

Representative items in decreasing order of loading for each of the four dimensions.

<p>Representative items in decreasing order of loading for each of the four dimensions.</p