812 research outputs found

    Quark model with Hidden Local Symmetry and its application to TccT_{cc}

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    We propose a chiral quark model including the ω\omega and ρ\rho meson contributions in addition to the π\pi and σ\sigma meson contributions. We show that the masses of the ground state baryons such as the nucleon, Λc\Lambda_c and Λb\Lambda_b are dramatically improved in the model with the vector mesons compared with the one without them. The study of the tetraquark TccT_{cc} is also performed in a coupled channel calculation and the resultant mass is much closer to the experiment than the result without vector meson contribution. This approach could be applied in future study of multi-quark systems.Comment: 6 pages, 4 figure

    Implicit-explicit Integrated Representations for Multi-view Video Compression

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    With the increasing consumption of 3D displays and virtual reality, multi-view video has become a promising format. However, its high resolution and multi-camera shooting result in a substantial increase in data volume, making storage and transmission a challenging task. To tackle these difficulties, we propose an implicit-explicit integrated representation for multi-view video compression. Specifically, we first use the explicit representation-based 2D video codec to encode one of the source views. Subsequently, we propose employing the implicit neural representation (INR)-based codec to encode the remaining views. The implicit codec takes the time and view index of multi-view video as coordinate inputs and generates the corresponding implicit reconstruction frames.To enhance the compressibility, we introduce a multi-level feature grid embedding and a fully convolutional architecture into the implicit codec. These components facilitate coordinate-feature and feature-RGB mapping, respectively. To further enhance the reconstruction quality from the INR codec, we leverage the high-quality reconstructed frames from the explicit codec to achieve inter-view compensation. Finally, the compensated results are fused with the implicit reconstructions from the INR to obtain the final reconstructed frames. Our proposed framework combines the strengths of both implicit neural representation and explicit 2D codec. Extensive experiments conducted on public datasets demonstrate that the proposed framework can achieve comparable or even superior performance to the latest multi-view video compression standard MIV and other INR-based schemes in terms of view compression and scene modeling

    Electric pulses can influence galvanotaxis of Dictyostelium discoideum

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    Galvanotaxis, or electrotaxis, plays an essential role in wound healing, embryogenesis, and nerve regeneration. Up until now great efforts have been made to identify the underlying mechanism related to galvanotaxis in various cells under direct current electric field (DCEF) in laboratory studies. However, abundant clinical research shows that non-DCEFs including monopolar or bipolar electric field may also contribute to wound healing and regeneration, although the mechanism remains elusive. Here, we designed a novel electric stimulator and applied DCEF, pulsed DCEF (pDCEF), and bipolar pulse electric field (bpEF) to the cells of Dictyostelium discoideum. The cells had better directional performance under asymmetric 90% duty cycle pDCEF and 80% duty cycle bpEF compared to DCEF, with 10 Hz frequency electric fields eliciting a better cell response than 5 Hz. Interestingly, electrically neutral 50% duty cycle bpEF triggered the highest migration speed, albeit in random directions. The results suggest that electric pulses are vital to galvanotaxis and non-DCEF is promising in both basic and clinical researches

    Pelletization performance of Panzhihua ilmenite concentrate

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    The influences of particle size distribution and the binder on the pelletization performance of Panzhihua ilmenite concentrate were studied in this paper. The results showed that the particle size distribution of Panzhihua ilmenite concentrate has the most important on its pelletization. The particle size distribution of ilmenite concentrate was significant changed and the specific surface area increased after grinding. The particle size of 45μm should be controlled less than 55% and 74μm no more than 74% in order to acquire a better performance of pellets. While the same performance of pellets can be obtained when the specific surface area of ilmenite concentrate was 1493cm2/g. The performance of pellets added with an organic binder is better than added bentonite. The pellet’s performance could be further improved under the mixed ratio of 1.05% bentonite and 0.45% organic binder

    Effects of cyclin-dependent kinase 8 specific siRNA on the proliferation and apoptosis of colon cancer cells

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    <p>Abstract</p> <p>Background</p> <p>To investigate the expression of cyclin-dependent kinase 8 (CDK8) and β-catenin in colon cancer and evaluate the role of CDK8 in the proliferation, apoptosis and cell cycle progression of colon cancer cells, especially in HCT116 cell line.</p> <p>Methods</p> <p>Colon cancer cell line HCT116 was transfected with small interfering RNA (siRNA) targeting on CDK8. After CDK8-siRNA transfection, mRNA and protein expression levels of CDK8 and β-catenin were determined by reverse transcriptase-polymerase chain reaction (RT-PCR) and Western blot assay in HCT116 cells. Cell proliferation was measured by 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide Methylthiazolyl tetrazolium (MTT) assay, and cell cycle distribution and apoptosis were analyzed by flow cytometry analysis (FACS). CDK8 and β-catenin protein levels were also examined by real-time PCR and immunohistochemistry (IHC) in colon cancer tissues and adjacent normal tissues.</p> <p>Results</p> <p>After CDK8 specific siRNA transfection, mRNA and protein expression levels of CDK8 and β-catenin in HCT116 cells were noticeably decreased (<it>P </it>< 0.05). CDK8 specific siRNA transfection inhibited HCT116 cells' proliferation and facilitated their apoptosis significantly (<it>P </it>< 0.05). In addition, the proportion of HCT116 cells in the G0/G1 phase was remarkably increased after CDK8-siRNA transfection (<it>P </it>< 0.05). The expression levels of CDK8 and β-catenin in adjacent normal tissues were lower than in tumor tissues (<it>P </it>< 0.05). Moreover, the expression of CDK8 was correlated with the expression of β-catenin in both tumor and adjacent normal tissues (<it>P </it>< 0.05).</p> <p>Conclusions</p> <p>CDK8 and β-catenin were expressed in colon cancer at a high frequency. CDK8 specific siRNA transfection down-regulated the expression of CDK8 in colon cancer cells, which was also associated with a decrease in the expression of β-catenin Moreover, CDK8 specific siRNA inhibited the proliferation of colon cancer cells, promoted their apoptosis and arrested these cells in the G0/G1 phase. Interference of CDK8 might be an effective strategy through β-catenin regulation of colon cancer.</p

    CO2 assimilation, ribulose-1,5-bisphosphate carboxylase/oxygenase, carbohydrates and photosynthetic electron transport probed by the JIP-test, of tea leaves in response to phosphorus supply

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    <p>Abstract</p> <p>Background</p> <p>Although the effects of P deficiency on tea (<it>Camellia sinensis </it>(L.) O. Kuntze) growth, P uptake and utilization as well as leaf gas exchange and Chl a fluorescence have been investigated, very little is known about the effects of P deficiency on photosynthetic electron transport, photosynthetic enzymes and carbohydrates of tea leaves. In this study, own-rooted 10-month-old tea trees were supplied three times weekly for 17 weeks with 500 mL of nutrient solution at a P concentration of 0, 40, 80, 160, 400 or 1000 μM. This objective of this study was to determine how P deficiency affects CO<sub>2 </sub>assimilation, Rubisco, carbohydrates and photosynthetic electron transport in tea leaves to understand the mechanism by which P deficiency leads to a decrease in CO<sub>2 </sub>assimilation.</p> <p>Results</p> <p>Both root and shoot dry weight increased as P supply increased from 0 to 160 μM, then remained unchanged. P-deficient leaves from 0 to 80 μM P-treated trees showed decreased CO<sub>2 </sub>assimilation and stomatal conductance, but increased intercellular CO<sub>2 </sub>concentration. Both initial and total Rubisco activity, contents of Chl and total soluble protein in P-deficient leaves decreased to a lesser extent than CO<sub>2 </sub>assimilation. Contents of sucrose and starch were decreased in P-deficient leaves, whereas contents of glucose and fructose did not change significantly except for a significant increase in the lowest P leaves. OJIP transients from P-deficient leaves displayed a rise at the O-step and a depression at the P-step, accompanied by two new steps at about 150 μs (L-step) and at about 300 μs (K-step). RC/CS<sub>o</sub>, TR<sub>o</sub>/ABS (or F<sub>v</sub>/F<sub>m</sub>), ET<sub>o</sub>/ABS, RE<sub>o</sub>/ABS, maximum amplitude of IP phase, PI<sub>abs </sub>and PI<sub>tot, abs </sub>were decreased in P-deficient leaves, while V<sub>J</sub>, V<sub>I </sub>and dissipated energy were increased.</p> <p>Conclusion</p> <p>P deficiency decreased photosynthetic electron transport capacity by impairing the whole electron transport chain from the PSII donor side up to the PSI, thus decreasing ATP content which limits RuBP regeneration, and hence, the rate of CO<sub>2 </sub>assimilation. Energy dissipation is enhanced to protect P-deficient leaves from photo-oxidative damage in high light.</p

    InstructME: An Instruction Guided Music Edit And Remix Framework with Latent Diffusion Models

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    Music editing primarily entails the modification of instrument tracks or remixing in the whole, which offers a novel reinterpretation of the original piece through a series of operations. These music processing methods hold immense potential across various applications but demand substantial expertise. Prior methodologies, although effective for image and audio modifications, falter when directly applied to music. This is attributed to music's distinctive data nature, where such methods can inadvertently compromise the intrinsic harmony and coherence of music. In this paper, we develop InstructME, an Instruction guided Music Editing and remixing framework based on latent diffusion models. Our framework fortifies the U-Net with multi-scale aggregation in order to maintain consistency before and after editing. In addition, we introduce chord progression matrix as condition information and incorporate it in the semantic space to improve melodic harmony while editing. For accommodating extended musical pieces, InstructME employs a chunk transformer, enabling it to discern long-term temporal dependencies within music sequences. We tested InstructME in instrument-editing, remixing, and multi-round editing. Both subjective and objective evaluations indicate that our proposed method significantly surpasses preceding systems in music quality, text relevance and harmony. Demo samples are available at https://musicedit.github.io/Comment: Demo samples are available at https://musicedit.github.io
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