8 research outputs found
Gene variants polymorphisms and uterine leiomyoma: an updated review
Uterine leiomyoma, commonly referred to as fibroids, is a benign tumor that develops in the muscular wall of the uterus. These growths are non-cancerous and can vary in size, ranging from tiny nodules to larger masses. Uterine leiomyomas often occur during a woman’s reproductive years and can lead to symptoms such as heavy menstrual bleeding, pelvic pain, and pressure on nearby organs. While the exact cause is not fully understood, hormonal factors, particularly estrogen and progesterone, are believed to play a role in their development. The exploration of connections between genetic variants and uterine leiomyoma has captivated scientific attention for numerous years. The results from investigations remain a subject of intrigue within the scientific community. To date, the findings regarding the relationships between single nucleotide polymorphisms (SNPs) and uterine leiomyoma have exhibited some inconsistencies. However, amidst these inconsistencies, several promising outcomes have emerged that hold the potential to shape future research endeavors. These promising leads could pave the way for the development of innovative targeted therapies and novel prognostic biomarkers. This review specifically centers on accentuating the existing literature data concerning genetic variants that have been explored for their potential connections to uterine leiomyoma. Additionally, it underscores the prospects of employing genetic variations as diagnostic and prognostic biomarkers for individuals diagnosed with uterine leiomyoma
Assessment of changes in risk factors of metabolic syndrome
Background: Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus and all causes mortality. The present study was conducted to assess changes in risk factors of metabolic syndrome. Materials & Methods: 80 subjects in age ranged 20-40 years of both genders were included. Height, weight, body mass index and various risk factors for metabolic syndrome such as waist circumference, blood pressure, fasting blood sugar, triglycerides and high-density lipoprotein were assessed at baseline and after one year. International Physical Activity Questionnaire (IPAQ) was used to objectively assess physical activity levels of the participants. Results: Total score of walking (MET-minutes/week) was 452.6 and 832.9, total moderate activity (MET-minutes/week) was 432.5 and 625.4, total vigorous activity (MET-minutes/week) was 80.4 and 124.6, total physical activity (MT-minutes/week) was 1214.5 and 1854.2, sitting total (minutes/week) was 3650.2 and 2652.8 and average sitting minutes/day was 524.0 and 375.2. The difference was significant (P< 0.05). Conclusion: There was reduction in waist circumference and triglyceride level over 1 year
Abstracts of National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020
This book presents the abstracts of the papers presented to the Online National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020 (RDMPMC-2020) held on 26th and 27th August 2020 organized by the Department of Metallurgical and Materials Science in Association with the Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, India.
Conference Title: National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020Conference Acronym: RDMPMC-2020Conference Date: 26–27 August 2020Conference Location: Online (Virtual Mode)Conference Organizer: Department of Metallurgical and Materials Engineering, National Institute of Technology JamshedpurCo-organizer: Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, IndiaConference Sponsor: TEQIP-