32 research outputs found

    Understanding medical students’ empathy based on Enneagram personality types

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    Purpose High self-awareness can promote communication and empathy. The Enneagram is a well-known personality tool to enhance self-awareness. We evaluated differences in empathy among medical students using the Enneagram typology. Methods This cross-sectional study included first and second grade students at the Inje University College of Medicine. The Jefferson Scale of Empathy was used to measure empathy and the Korean Enneagram Personality Type Indicator was used for examining personality characteristics. Empathy scores were analyzed according to the Triads, Hornevian group, Harmonic group, and each Enneagram type. Results The Instinctive triad, the Withdrawns, and the Positive outlook group were the most common, and the Feeling triad, the Assertives, and the Emotional realness group were the least common. Students in the Feeling triad and the Dutifuls had higher compassionate care (CC) scores as compared to their counterparts. Type 2 and 6 students showed the two highest empathy and CC scores. The empathy score of type 3 students was the lowest. Type 7 had the lowest CC score but the highest perspective taking score. Conclusion These differences in empathy according to Enneagram personality types can be applied to medical education to maintain and improve medical students’ empathy

    Generation of double knockout cattle via CRISPR-Cas9 ribonucleoprotein (RNP) electroporation

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    Background Genome editing has been considered as powerful tool in agricultural fields. However, genome editing progress in cattle has not been fast as in other mammal species, for some disadvantages including long gestational periods, single pregnancy, and high raising cost. Furthermore, technically demanding methods such as microinjection and somatic cell nuclear transfer (SCNT) are needed for gene editing in cattle. In this point of view, electroporation in embryos has been risen as an alternative. Results First, editing efficiency of our electroporation methods were tested for embryos. Presence of mutation on embryo was confirmed by T7E1 assay. With first combination, mutation rates for MSTN and PRNP were 57.6% ± 13.7% and 54.6% ± 13.5%, respectively. In case of MSTN/BLG, mutation rates were 83.9% ± 23.6% for MSTN, 84.5% ± 18.0% for BLG. Afterwards, the double-KO embryos were transferred to surrogates and mutation rate was identified in resultant calves by targeted deep sequencing. Thirteen recipients were transferred for MSTN/PRNP, 4 calves were delivered, and one calf underwent an induction for double KO. Ten surrogates were given double-KO embryos for MSTN/BLG, and four of the six calves that were born had mutations in both genes. Conclusions These data demonstrated that production of genome edited cattle via electroporation of RNP could be effectively applied. Finally, MSTN and PRNP from beef cattle and MSTN and BLG from dairy cattle have been born and they will be valuable resources for future precision breeding.This study was financially supported by the National Research Foundation of Korea (NRF-2021R1A5A1033157 for SRC program: 382 Comparative medicine Disease Research Center; NRF-2021R1F1A105195313), the Research Institute of Veterinary Science, the BK21 Four for Future Veterinary Medicine Leading Education and Research Center, and a Seoul National University (SNU) grant (#550e2020005

    Assessing future changes in the East Asian summer monsoon using CMIP5 coupled models

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    Future changes in the East Asian summer monsoon (EASM) are estimated from historical and Representative Concentration Pathway 6.0 (RCP6) experiments of the fifth phase of the Coupled Model Intercomparison Project (CMIP5). The historical runs show that, like the CMIP3 models, the CMIP5 models produce slightly smaller precipitation. A moisture budget analysis illustrates that this precipitation deficit is due to an underestimation in evaporation and ensuing moisture flux convergence. Of the two components of the moisture flux convergence (i.e., moisture convergence and horizontal moist advection), moisture convergence associated with mass convergence is underestimated to a greater degree. Precipitation is anticipated to increase by 10%-15% toward the end of the twenty-first century over the major monsoonal front region. A statistically significant increase is predicted to occur mostly over the Baiu region and to the north and northeast of the Korean Peninsula. This increase is attributed to an increase in evaporation and moist flux convergence (with enhanced moisture convergence contributing the most) induced by the northwestward strengthening of the North Pacific subtropical high (NPSH), a characteristic feature of the future EASM that occurred in CMIP5 simulations. Along the northern and northwestern flank of the strengthened NPSH, intensified southerly or southwesterly winds lead to the increase in moist convergence, enhancing precipitation over these areas. However, future precipitation over the East China Sea is projected to decrease. In the EASM domain, a local mechanism prevails, with increased moisture and moisture convergence leading to a greater increase in moist static energy in the lower troposphere than in the upper troposphere, reducing tropospheric stability.open6

    Influence of Surface Roughness and Agitation on the Morphology of Magnetite Films Electrodeposited on Carbon Steel Substrates

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    In this work, we investigated the effects of surface roughness and agitation on the morphology of magnetite films electrodeposited from alkaline Fe(III)-triethanolamine (TEA) solutions on carbon steel substrates. The surface roughness of the carbon steel substrates was maintained in the range of 1.64–0.06 μm by using mechanical grinding and polishing methods. The agitation speed was set at 0 and 900 rpm during the electrodeposition process. The particle size and surface roughness value of the magnetite films gradually decreased with decreasing substrate roughness. However, the influence of the substrate roughness on the thickness of the magnetite film was negligible. The morphology of the magnetite film fabricated at 900 rpm appeared to be highly faceted compared to that of the magnetite film produced at 0 rpm. The thickness and surface roughness of the magnetite film significantly increased with the agitation speed, which also significantly affected the electrodeposition efficiency. The effects of substrate surface roughness and agitation on the morphology of magnetite films electrodeposited on carbon steel substrates were also discussed. The obtained results provide critical information for the simulation of magnetite deposits on carbon steel pipes in the secondary systems of nuclear power plants

    High Sensitive pH Sensor Based on AlInN/GaN Heterostructure Transistor

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    The AlInN/GaN high-electron-mobility-transistor (HEMT) indicates better performances compared with the traditional AlGaN/GaN HEMTs. The present work investigated the pH sensor functionality of an analogous HEMT AlInN/GaN device with an open gate. It was shown that the Al0.83In0.17N/GaN device demonstrates excellent pH sense functionality in aqueous solutions, exhibiting higher sensitivity (−30.83 μA/pH for AlInN/GaN and −4.6 μA/pH for AlGaN/GaN) and a faster response time, lower degradation and good stability with respect to the AlGaN/GaN device, which is attributed to higher two-dimensional electron gas (2DEG) density and a thinner barrier layer in Al0.83In0.17N/GaN owning to lattice matching. On the other hand, the open gate geometry was found to affect the pH sensitivity obviously. Properly increasing the width and shortening the length of the open gate area could enhance the sensitivity. However, when the open gate width is too larger or too small, the pH sensitivity would be suppressed conversely. Designing an optimal ratio of the width to the length is important for achieving high sensitivity. This work suggests that the AlInN/GaN-based 2DEG carrier modulated devices would be good candidates for high-performance pH sensors and other related applications

    Corrosion Behavior of SA508 Coupled with and without Magnetite in EDTA-Based Solutions

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    The effects of magnetite on the corrosion behavior of SA508 were studied in 10% and 20% EDTA-based chemical cleaning solutions at 93 °C and 121 °C using electrochemical and immersion tests. SA508 was the anode of the galvanic pair between SA508 and magnetite. The galvanic coupling shifted the mixed corrosion potential of SA508 in the positive direction and thus increased its corrosion rate. The increase of the EDTA concentration and solution temperature led to an increase in the extent of the galvanic effect

    Fabrication of AlGaN/GaN Ω-shaped nanowire fin-shaped FETs by a top-down approach

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    International audienceAn AlGaN/GaN-based Ω-shaped nanowire fin-shaped FET (FinFET) with a fin width of 50 nm was fabricated using tetramethylammonium hydroxide (TMAH)-based lateral wet etching. An atomic layer deposited (ALD) HfO2 side-wall layer served as the etching mask. ALD Al2O3 and TiN layers were used as the gate dielectric and gate metal, respectively. The Ω-shaped gate structure fully depletes the active fin body and almost completely separates the depleted fin from the underlying thick GaN buffer layer, resulting in superior device performance. The top-down processing proposed in this work provides a viable pathway towards gate-all-around devices for III–nitride semiconductors

    Normally-off AlGaN/GaN-based MOS-HEMT with self-terminating TMAH wet recess etching

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    International audienceNormally-off AlGaN/GaN-based MOS-HEMT has been fabricated by utilizing damage-free self-terminating tetramethyl ammonium hydroxide (TMAH) recess etching. The device exhibited a threshold voltage of +2.0 V with good uniformity, extremely small hysteresis of ∼20 mV, and maximum drain current of 210 mA/mm. The device also exhibited excellent off-state performances, such as breakdown voltage of ∼800 V with off-state leakage current as low as ∼10−12 A and high on/off current ratio (Ion/Ioff) of 1010. These excellent device performances are believed to be due to the high quality recessed surface, provided by the simple self-terminating TMAH etching. Previous article in issu

    Performance of AlGaN/GaN Nanowire Omega-Shaped-Gate Fin-Shaped Field-Effect Transistor

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    International audienceThe AlGaN/GaN nanowire omega-shaped-gate FinFET have been successfully fabricated demonstrating much improved performance compared to conventional AlGaN/GaN MISHFET. The AlGaN/GaN omega-shaped-gate FinFET exhibited the remarkable on-state performances, such as maximum drain current of 1.1 A/mm, low on-resistance, and low current collapse compared to that of the conventional device structure. In addition, the excellent off-state performances were measured: low off-state leakage current as low as ∼10−10 mA, the theoretical SS value of ∼62 mV/dec, and high I ON /I OFF ratio (∼109). Improved dc performances were obtained for omega-shaped-gate structure due to the fully depletion of the active fin body and perfectly separation of the depleted fin from the underlying thick GaN buffer layer. Furthermore, the additional reason for the enhanced device performance of the proposed device is the improved gate controllability compared to the conventional MISHFET. The proposed nano-structure device is very promising candidate for the steep switching device applications
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