21 research outputs found
IGF2 mRNA binding protein 3 (IMP3) promotes glioma cell migration by enhancing the translation of RELA/p65
Full text linkFibroblast Migration in 3D is Controlled by Haptotaxis in a Non-muscle Myosin II-Dependent Manner
Get PDFCell migration in 3D is a key process in many physiological and pathological processes. Although valuable knowledge has been accumulated through analysis of various 2D models, some of these insights are not directly applicable to migration in 3D. In this study, we have confined biomimetic hydrogels within microfluidic platforms in the presence of a chemoattractant (platelet-derived growth factor-BB). We have characterized the migratory responses of human fibroblasts within them, particularly focusing on the role of non-muscle myosin II. Our results indicate a prominent role for myosin II in the integration of chemotactic and haptotactic migratory responses of fibroblasts in 3D confined environments.Grants:
EUR/7FP/ERC-2012-StG 306751
ES/MINECO - DPI2012-38090-C03-01
ES/MINECO - SAF2011- 2495
Association between demographic features and perceived social support in the mental adjustment to breast cancer
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A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons
No full textResilience and burden in caregivers of older adults: moderating and mediating effects of perceived social support
No full textSynthesis and Characterization of Some Transition Metal Complexes with Mixed Adenine and Acetylacetonate Ligands: Crystal Structures of Solvated Complex {[Cu(acac)2(adenine)]·EtOH} and {[Cu(acac)2(adenine)]·DMF·H2O}
No full textInteractions of fibroblasts with the extracellular matrix: implications for the understanding of fibrosis
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An in vitro Comparison of Endodontic Medicaments Propolis and Calcium Hydroxide alone and in Combination with Ciprofloxacin and Moxifloxacin against Enterococcus Faecalis
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