2 research outputs found
Survival of patients receiving a liver transplant for hepatocellular carcinoma, and risk of tumor recurrence
Objective: the goal of this research has been to evaluate the
survival, in long and short term, of the patient receiving liver
transplant for hepatocellular carcinoma (HCC), the risk of posttransplant
tumor relapse and factors related to this complication.
Design: retrospective study of a consecutive series of patients
having had liver transplant for HCC.
Patients and methodology: transplant patients for HCC from
1989 to November 2003. Patients were selected due to general limitations
of nodule size and quantity, which were subsequently published
as Milan criteria. Also, criteria agreed in the Conference of
Barcelona were followed in the pre-transplant diagnosis.
Results: the survival of this 81 patients group was of the 80,
61 and 52% for 1, 5 and 10 years respectively. In the 32% of the
cases the HCC was an incidental finding in the explant. In the
12.3%, the tumor relapse was verified. The multivariate research
identified the size of the nodule (OR = 1,7944) (IC 95% =
1,1332-2,8413) and the vascular invasion (OR = 6,6346) (IC
95% = 1,4624-30,1003) as risk factors of relapse.
Conclusions: the liver transplant in selected patients with HCC
has good results in medium and long term. The risk of post-transplant
tumor relapse becomes notably reduced and is associated with
the size of the nodule and the microscopic vascular invasion
Wernicke's encephalopathy after cephalic pancreaticoduodenectomy Encefalopatía de Wernicke tras duodenopancreatectomía cefálica
Wernicke's encephalopathy is an acute neurological disorder resulting from thiamine deficiency. We report a case in a young patient who underwent a cephalic duodenopancreatectomy with a bleeding duodenal ulcer refractory to endoscopic and surgical treatment, requiring total parenteral nutrition, without thiamine supplementation.La encefalopatía de Wernicke (EW) es un trastorno neurológico agudo resultado del déficit de tiamina. Presentamos la aparición de dicho cuadro en un enfermo joven que es sometido a una duodenopancreatectomía cefálica ante una úlcera duodenal sangrante refractaria a tratamiento endoscópico y quirúrgico previo, precisando de una nutrición parenteral total, sin suplementos de tiamina