15 research outputs found
Cholinergic nerve terminals contain ascorbic acid which induces Ca2+-dependent release of acetylcholine and ATP from isolated Torpedo synaptic vesicles
Kinetic and cross-linking studies indicate different receptors for endothelins and sarafotoxins in the ileum and cerebellum
AbstractKinetics of ligand/receptor interactions using ET-1, ET-3 and SRTX-b were studied and cross-linking experiments carried out in guinea pig ileum and rat cerebellar preparations. Dissociation studies indicate that the two regions are characterized by different receptor subtypes and different modes of ligand binding. Autoradiographic patterns obtained following cross-linking of ET-1 and ET-3 to the different issues support these conclusions