2 research outputs found
Isolated cervical spinal canal stenosis at C-1 in the pediatric population and in Williams syndrome
The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVIDā19
Background Clinical and radiographic outcomes after mechanical thrombectomy in the setting of COVIDā19 infection remain poorly characterized. We sought to determine how COVIDā19 status affects mechanical thrombectomy outcomes in the realāworld setting in the United States. Methods The prospectively maintained multicenter mechanical thrombectomy registry from the Society of Vascular and Interventional Neurology was queried for baseline clinical characteristics among patients with and without COVIDā19 who underwent mechanical thrombectomy between March 1 and December 31, 2020 at 12 sites. Primary outcome was the likelihood of good neurological outcomes (90 day modified Rankin scale 0ā2) among patients with COVIDā19 treated with endovascular thrombectomy, which was assessed using multivariable logistic regression adjusted for age, National Institutes of Health Stroke Scale, Alberta Stroke Program Early CT Score, and substantial reperfusion (modified Thrombolysis in Cerebral Infarction 2b, 2c, and 3). Secondary outcomes included National Institutes of Health Stroke Scale at 24Ā hours. Results Among 915 patients who underwent mechanical thrombectomy during the study period, 51 patients were positive for COVIDā19 (5.6%). Univariate analysis revealed that compared with patients who were COVIDā19 negative, patients who were positive for COVIDā19 were more likely to be male, nonsmokers, have lower Alberta Stroke Program Early CT Score, and present with intracranial internal carotid artery occlusions (Table 1). They were also less likely to achieve successful reperfusion. Multivariable analysis, however, failed to identify any independent associations with COVIDā19 positive status. Conclusion In our cohort, patients postive for COVIDā19 with acute ischemic stroke who undergo mechanical thrombectomy have similar baseline characteristics, imaging features, procedural, and clinical outcomes compared to patients who are negative for COVIDā19 in multivariate analysis. Further analyses are warranted