67 research outputs found

    ASSESSING PATIENT SATISFACTION FOR INVESTIGATIVE SERVICES AT PUBLIC HOSPITALS TO IMPROVE QUALITY OF SERVICES

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    ABSTRACT Objective: The main objective of the paper is to assess the satisfaction level of investigative patients at public health facilities of Madhya Pradesh, a State of India. Methods: Data were collected from investigative patients through structured questionnaires at public health facilities in the sampled eight districts of Madhya Pradesh. Settings: Data were collected from District Hospitals, Civil Hospitals and Community Health Centers of the eight selected districts of Madhya Pradesh. esults: A total of 280 investigative patients were included in the study to know their perceptions about the services at the public health facilities. It was found that most of the respondents belong to rural areas (53.9%) and majority (82.1%) lies within the age group of 16-50. 56.4% were male having low level of literacy. 90% of the respondents who availed ultrasonography services and nearly 70% of the investigative patients who have utilized ECG facility found the problem of overcrowding but found the test facility good. However, 67.3% and 76% of the patients reported that the test facility was good who availed the services of laboratory and X-Ray. More than 80% of the total investigative patients reported the behavior of the technicians as good. Nearly 50% of the respondents who availed the services of laboratory and X-ray, reported that privacy and confidentiality was good whereas rest found it satisfactory

    Assessing Indian public health standards for community health centers: A case study with special reference to essential newborn care services

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    The main objective of the study is to identify the availability of infrastructure facility, human resources, investigative services, and facility based newborn care services with respect to Indian Public Health Standards (IPHS) at community health centers (CHC) of Bharatpur District of Rajasthan State. Data were collected from service providers at CHC through well structured questionnaire at thirteen CHCs situated at Bharatpur District of Rajasthan State. It was found that infrastructure facilities were available in almost all the CHCs, but shortage of manpower especially specialists was observed. Availability of investigative services was found quite satisfactory except ECG. It was also observed that none of the CHCs have fully equipped facility based newborn care services (including newborn corner and newborn care stabilization unit). As per IPHS suggested in the revised draft (2010) important deficiencies were revealed in the studied CHCs of Bharatpur district and by additional inputs such as recruiting staff, improving infrastructure facilities, CHCs can be upgraded

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    Aspetti energetici e ambientali di un impianto di trigenerazione

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    Vengono descritti gli aspetti energetici ed ambientali relativi alla realizzazione di un sistema per la produzione combinata di energia elettrica, calore e acqua refrigerata (tri-generazione) con un sistema basato su micro-turbina a gas, Il sistema sarà costituito da una microturbina alimentata a gas metano per la produzione di energia elettrica, dotata di uno scambiatore di recupero dell’energia termica dei fumi, in grado di fornire energia termica utilizzabile per il soddisfacimento dei fabbisogni energetici invernali o per l’alimentazione di una macchina ad assorbimento, ai fini di provvedere alle necessità di condizionamento estivo dell’aria negli ambienti tramite la produzione di acqua refrigerata. Il sistema presenta indubbi benefici economici, per il risparmio sul costo dell'energia elettrica autoprodotta e sulla potenza installata. In media l'impianto si ripaga in 4-5 anni con un utilizzo di almeno 3000 - 4000 ore l'anno) e ambientali, in quanto rispetto alla generazione separata di energia elettrica e termica, la cogenerazione riduce del 30-40% la quantità di combustibile utilizzato, e quindi le emissioni inquinanti

    Treatment of intermetatarsal neuromas with alcohol injection under US guide.

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    The cause of intermetatarsal neuromas is unclear; the pathogenesis is, most likely, a mechanically induced degenerative neuropathy or an entrapment of the intermetatarsal nerve under the transverse intermetatarsal ligament. Treatment of intermetatarsal neuromas includes very simple methods, such as changing shoe styles, or more complex conservative treatments such as orthotic devices and steroid injections until surgical therapy. This study aimed to evaluate the neuroma's intralesional treatment with alcohol sclerosing injection as a viable alternative to steroid injections or surgery in persisting symptoms

    Treatment of intermetatarsal neuromas with alcohol injection under US guide.

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    The cause of intermetatarsal neuromas is unclear; the pathogenesis is, most likely, a mechanically induced degenerative neuropathy or an entrapment of the intermetatarsal nerve under the transverse intermetatarsal ligament. Treatment of intermetatarsal neuromas includes very simple methods, such as changing shoe styles, or more complex conservative treatments such as orthotic devices and steroid injections until surgical therapy. This study aimed to evaluate the neuroma's intralesional treatment with alcohol sclerosing injection as a viable alternative to steroid injections or surgery in persisting symptoms

    PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR

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    Multidrug resistance protein 7 (MRP7, ABCC10) is a recently identified member of the ATP-binding cassette (ABC) transporter family, which adequately confers resistance to a diverse group of antineoplastic agents, including taxanes, vinca alkaloids and nucleoside analogs among others. Clinical studies indicate an increased MRP7 expression in non-small cell lung carcinomas (NSCLC) compared to a normal healthy lung tissue. Recent studies revealed increased paclitaxel sensitivity in the Mrp7−/− mouse model compared to their wild-type counterparts. This demonstrates that MRP7 is a key contributor in developing drug resistance. Recently our group reported that PD173074, a specific fibroblast growth factor receptor (FGFR) inhibitor, could significantly reverse P-glycoprotein-mediated MDR. However, whether PD173074 can interact with and inhibit other MRP members is unknown. In the present study, we investigated the ability of PD173074 to reverse MRP7-mediated MDR. We found that PD173074, at non-toxic concentration, could significantly increase the cellular sensitivity to MRP7 substrates. Mechanistic studies indicated that PD173074 (1 μmol/L) significantly increased the intracellular accumulation and in-turn decreased the efflux of paclitaxel by inhibiting the transport activity without altering expression levels of the MRP7 protein, thereby representing a promising therapeutic agent in the clinical treatment of chemoresistant cancer patients
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