Derivative based global sensitivity measures

The method of derivative based global sensitivity measures (DGSM) has recently become popular among practitioners. It has a strong link with the Morris screening method and Sobol' sensitivity indices and has several advantages over them. DGSM are very easy to implement and evaluate numerically. The computational time required for numerical evaluation of DGSM is generally much lower than that for estimation of Sobol' sensitivity indices. This paper presents a survey of recent advances in DGSM concerning lower and upper bounds on the values of Sobol' total sensitivity indices $S\_{i}^{tot}$. Using these bounds it is possible in most cases to get a good practical estimation of the values of $S\_{i}^{tot}$. Several examples are used to illustrate an application of DGSM

Influence of backreaction of electric fields and Schwinger effect on inflationary magnetogenesis

We study the generation of electromagnetic fields during inflation when the conformal invariance of Maxwell's action is broken by the kinetic coupling $f^{2}(\phi)F_{\mu\nu}F^{\mu\nu}$ of the electromagnetic field to the inflaton field $\phi$. We consider the case where the coupling function $f(\phi)$ decreases in time during inflation and, as a result, the electric component of the energy density dominates over the magnetic one. The system of equations which governs the joint evolution of the scale factor, inflaton field, and electric energy density is derived. The backreaction occurs when the electric energy density becomes as large as the product of the slow-roll parameter $\epsilon$ and inflaton energy density, $\rho_{E}\sim \epsilon \rho_{\rm inf}$. It affects the inflaton field evolution and leads to the scale-invariant electric power spectrum and the magnetic one which is blue with the spectral index $n_{B}=2$ for any decreasing coupling function. This gives an upper limit on the present-day value of observed magnetic fields below $10^{-22}\,{\rm G}$. It is worth emphasizing that since the effective electric charge of particles $e_{\rm eff}=e/f$ is suppressed by the coupling function, the Schwinger effect becomes important only at the late stages of inflation when the inflaton field is close to the minimum of its potential. The Schwinger effect abruptly decreases the value of the electric field, helping to finish the inflation stage and enter the stage of preheating. It effectively produces the charged particles, implementing the Schwinger reheating scenario even before the fast oscillations of the inflaton. The numerical analysis is carried out in the Starobinsky model of inflation for the powerlike $f\propto a^{\alpha}$ and Ratra-type $f=\exp(\beta\phi/M_{p})$ coupling functions.Comment: 21 pages, 8 figure

Microbial single-cell omics: the crux of the matter

Single-cell genomics and transcriptomics can provide reliable context for assembled genome fragments and gene expression activity on the level of individual prokaryotic genomes. These methods are rapidly emerging as an essential complement to cultivation-based, metagenomics, metatranscriptomics, and microbial community-focused research approaches by allowing direct access to information from individual microorganisms, even from deep-branching phylogenetic groups that currently lack cultured representatives. Their integration and binning with environmental ‘omics data already provides unprecedented insights into microbial diversity and metabolic potential, enabling us to provide information on individual organisms and the structure and dynamics of natural microbial populations in complex environments. This review highlights the pitfalls and recent advances in the field of single-cell omics and its importance in microbiological and biotechnological studies

Derivative based global sensitivity measures

International audienceThe method of derivative based global sensitivity measures (DGSM) has recently become popular among practitioners. It has a strong link with the Morris screening method and Sobol' sensitivity indices and has several advantages over them. DGSM are very easy to implement and evaluate numerically. The computational time required for numerical evaluation of DGSM is generally much lower than that for estimation of Sobol' sensitivity indices. This paper presents a survey of recent advances in DGSM concerning lower and upper bounds on the values of Sobol' total sensitivity indices $S_{i}^{tot}$. Using these bounds it is possible in most cases to get a good practical estimation of the values of $S_{i}^{tot}$. Several examples are used to illustrate an application of DGSM

Sensitivity analysis methods for uncertainty budgeting in system design

Quantification and management of uncertainty are critical in the design of engineering systems, especially in the early stages of conceptual design. This paper presents an approach to defining budgets on the acceptable levels of uncertainty in design quantities of interest, such as the allowable risk in not meeting a critical design constraint and the allowable deviation in a system performance metric. A sensitivity-based method analyzes the effects of design decisions on satisfying those budgets, and a multi-objective optimization formulation permits the designer to explore the tradespace of uncertainty reduction activities while also accounting for a cost budget. For models that are computationally costly to evaluate, a surrogate modeling approach based on high dimensional model representation (HDMR) achieves efficient computation of the sensitivities. An example problem in aircraft conceptual design illustrates the approach.United States. National Aeronautics and Space Administration. Leading Edge Aeronautics Research Program (Grant NNX14AC73A)United States. Department of Energy. Applied Mathematics Program (Award DE-FG02-08ER2585)United States. Department of Energy. Applied Mathematics Program (Award DE-SC0009297

Effect of the Deposition Parameters on the Phase-Structure State, Hardness, and Tribological Characteristics of Mo2 N/CrN Vacuum - Arc Multilayer Coatings

A complex study has been performed of the effect of the technological parameters, which are responsible for the energy states of deposited particles, on the elemental, phase and structure compositions, hardness, and tribological characteristics of formed vacuum-arc multilayer Mo2N/CrN systems with a nanometric thickness. The formation of two phase and structure types has been defined in combined nitride layers: γ-Mo2N/CrN with the isostructural cubic crystalline lattices and γ-Mo2N/CrN with nonisostructural cubic and hexagonal lattice

Quantum dynamics in canonical and micro-canonical ensembles. Part I. Anderson localization of electrons

The new numerical approach for consideration of quantum dynamics and calculations of the average values of quantum operators and time correlation functions in the Wigner representation of quantum statistical mechanics has been developed. The time correlation functions have been presented in the form of the integral of the Weyl's symbol of considered operators and the Fourier transform of the product of matrix elements of the dynamic propagators. For the last function the integral Wigner- Liouville's type equation has been derived. The numerical procedure for solving this equation combining both molecular dynamics and Monte Carlo methods has been developed. For electrons in disordered systems of scatterers the numerical results have been obtained for series of the average values of the quantum operators including position and momentum dispersions, average energy, energy distribution function as well as for the frequency dependencies of tensor of electron conductivity and permittivity according to quantum Kubo formula. Zero or very small value of static conductivity have been considered as the manifestation of Anderson localization of electrons in 1D case. Independent evidence of Anderson localization comes from the behaviour of the calculated time dependence of position dispersion.Comment: 8 pages, 10 figure

Structure and properties of vacuum arc single-layer and multiperiod two-layer nitride coatings based on Ti(Al): Si layers

The paper provides an analysis of impact of deposition conditions on structural and phase state and thermal stability of vacuum arc coatings based on Ti(Al):Si layer

Single layer and multilayer vacuum-arc coatings based on the nitride tialsiyn: composition, structure, properties

Using high-technological vacuum-arc evaporation in the atmosphere of nitrogen with ion bombardment, single- and multilayer coatings based on TiAlSiYN with high mechanical characteristics were obtained: hardness of the coatings reached 49.5 GPA, resistance to wear, with the value of the critical point LC5 reaching 184.92 N. The mechanisms of structure formation, defining the resulting mechanical characteristics of single- and multi-layer coatings based on TiAlSiYN nitride have been discusse