13,185 research outputs found

    Making sense: talking data management with researchers

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    Incremental is one of eight projects in the JISC Managing Research Data programme funded to identify institutional requirements for digital research data management and pilot relevant infrastructure. Our findings concur with those of other Managing Research Data projects, as well as with several previous studies. We found that many researchers: (i) organise their data in an ad hoc fashion, posing difficulties with retrieval and re-use; (ii) store their data on all kinds of media without always considering security and back-up; (iii) are positive about data sharing in principle though reluctant in practice; (iv) believe back-up is equivalent to preservation. <br></br><br></br> The key difference between our approach and that of other Managing Research Data projects is the type of infrastructure we are piloting. While the majority of these projects focus on developing technical solutions, we are focusing on the need for ‘soft’ infrastructure, such as one-to-one tailored support, training, and easy-to-find, concise guidance that breaks down some of the barriers information professionals have unintentionally built with their use of specialist terminology. <br></br><br></br> We are employing a bottom-up approach as we feel that to support the step-by-step development of sound research data management practices, you must first understand researchers’ needs and perspectives. Over the life of the project, Incremental staff will act as mediators, assisting researchers and local support staff to understand the data management requirements within which they are expect to work, and will determine how these can be addressed within research workflows and the existing technical infrastructure. <br></br> <br></br> Our primary goal is to build data management capacity within the Universities of Cambridge and Glasgow by raising awareness of basic principles so everyone can manage their data to a certain extent. We will ensure our lessons can be picked up and used by other institutions. Our affiliation with the Digital Curation Centre and Digital Preservation Coalition will assist in this and all outputs will be released under a Creative Commons licence. The key difference between our approach and that of other MRD projects is the type of ‘infrastructure’ we are piloting. While the majority of these projects focus on developing technical solutions, we are focusing on the need for ‘soft’ infrastructure, such as one-to-one tailored support, training, and easy-to-find, concise guidance that breaks down some of the barriers information professionals have unintentionally built with their use of specialist terminology. We are employing a bottom-up approach as we feel that to support the step-by-step development of sound research data management practices, you must first understand researchers’ needs and perspectives. Over the life of the project, Incremental staff will act as mediators, assisting researchers and local support staff to understand the data management requirements within which they are expect to work, and will determine how these can be addressed within research workflows and the existing technical infrastructure. Our primary goal is to build data management capacity within the Universities of Cambridge and Glasgow by raising awareness of basic principles so everyone can manage their data to a certain extent. We’re achieving this by: - re-positioning existing guidance so researchers can locate the advice they need; - connecting researchers with one-to-one advice, support and partnering; - offering practical training and a seminar series to address key data management topics. We will ensure our lessons can be picked up and used by other institutions. Our affiliation with the Digital Curation Centre and Digital Preservation Coalition will assist in this and all outputs will be released under a Creative Commons licence

    New Insights on Interstellar Gas-Phase Iron

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    In this paper, we report on the gas-phase abundance of singly-ionized iron (Fe II) for 51 lines of sight, using data from the Far Ultraviolet Spectroscopic Explorer (FUSE). Fe II column densities are derived by measuring the equivalent widths of several ultraviolet absorption lines and subsequently fitting those to a curve of growth. Our derivation of Fe II column densities and abundances creates the largest sample of iron abundances in moderately- to highly-reddened lines of sight explored with FUSE, lines of sight that are on average more reddened than lines of sight in previous Copernicus studies. We present three major results. First, we observe the well-established correlation between iron depletion and and also find trends between iron depletion and other line of sight parameters (e.g. f(H_2), E_(B-V), and A_V), and examine the significance of these trends. Of note, a few of our lines of sight probe larger densities than previously explored and we do not see significantly enhanced depletion effects. Second, we present two detections of an extremely weak Fe II line at 1901.773 A in the archival STIS spectra of two lines of sight (HD 24534 and HD 93222). We compare these detections to the column densities derived through FUSE spectra and comment on the line's f-value and utility for future studies of Fe II. Lastly, we present strong anecdotal evidence that the Fe II f-values derived empirically through FUSE data are more accurate than previous values that have been theoretically calculated, with the probable exception of f_1112.Comment: Accepted for publication in ApJ, 669, 378; see ApJ version for small updates. 53 total pages (preprint format), 7 tables, 11 figure

    Incremental scoping study and implementation plan

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    This report is one of the first deliverables from the Incremental project, which seeks to investigate and improve the research data management infrastructure at the universities of Glasgow and Cambridge and to learn lessons and develop resources of value to other institutions. Coming at the end of the project’s scoping study, this report identifies the key themes and issues that emerged and proposes a set of activities to address those needs. As its name suggests, Incremental deliberately adopts a stepped, pragmatic approach to supporting research data management. It recognises that solutions will vary across different departmental and institutional contexts; and that top-down, policy-driven or centralised solutions are unlikely to prove as effective as practical support delivered in a clear and timely manner where the benefits can be clearly understood and will justify any effort or resources required. The findings of the scoping study have confirmed the value of this approach and the main recommendations of this report are concerned with the development and delivery of suitable resources. Although some differences were observed between disciplines, these seemed to be as much a feature of different organisational cultures as the nature of the research being undertaken. Our study found that there were many common issues across the groups and that the responses to these issues need not be highly technical or expensive to implement. What is required is that these resources employ jargon-free language and use examples of relevance to researchers and that they can be accessed easily at the point of need. There are resources already available (institutionally and externally) that can address researchers’ data management needs but these are not being fully exploited. So in many cases Incremental will be enabling efficient and contextualised access, or tailoring resources to specific environments, rather than developing resources from scratch. While Incremental will concentrate on developing, repurposing and leveraging practical resources to support researchers in their management of data, it recognises that this will be best achieved within a supportive institutional context (both in terms of policy and provision). The need for institutional support is especially evident when long-term preservation and data sharing are considered – these activities are clearly more effective and sustainable if addressed at more aggregated levels (e.g. repositories) rather than left to individual researchers or groups. So in addition to its work in developing resources, the Incremental project will seek to inform the development of a more comprehensive data management infrastructure at each institution. In Cambridge, this will be connected with the library’s CUPID project (Cambridge University Preservation Development) and at Glasgow in conjunction with the Digital Preservation Advisory Board

    Autonomous Attitude Determination System (AADS). Volume 1: System description

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    Information necessary to understand the Autonomous Attitude Determination System (AADS) is presented. Topics include AADS requirements, program structure, algorithms, and system generation and execution

    The effect of alpha(+)-thalassaemia on the incidence of malaria and other diseases in children living on the coast of Kenya

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    BACKGROUND: The alpha-thalassaemias are the commonest genetic disorders of humans. It is generally believed that this high frequency reflects selection through a survival advantage against death from malaria; nevertheless, the epidemiological description of the relationships between alpha-thalassaemia, malaria, and other common causes of child mortality remains incomplete. METHODS AND FINDINGS: We studied the alpha+-thalassaemia-specific incidence of malaria and other common childhood diseases in two cohorts of children living on the coast of Kenya. We found no associations between alpha+-thalassaemia and the prevalence of symptomless Plasmodium falciparum parasitaemia, the incidence of uncomplicated P. falciparum disease, or parasite densities during mild or severe malaria episodes. However, we found significant negative associations between alpha+-thalassaemia and the incidence rates of severe malaria and severe anaemia (haemoglobin concentration < 50 g/l). The strongest associations were for severe malaria anaemia (> 10,000 P. falciparum parasites/mul) and severe nonmalaria anaemia; the incidence rate ratios and 95% confidence intervals (CIs) for alpha+-thalassaemia heterozygotes and homozygotes combined compared to normal children were, for severe malaria anaemia, 0.33 (95% CI, 0.15,0.73; p = 0.006), and for severe nonmalaria anaemia, 0.26 (95% CI, 0.09,0.77; p = 0.015). CONCLUSIONS: Our observations suggest, first that selection for alpha+-thalassaemia might be mediated by a specific effect against severe anaemia, an observation that may lead to fresh insights into the aetiology of this important condition. Second, although alpha+-thalassaemia is strongly protective against severe and fatal malaria, its effects are not detectable at the level of any other malaria outcome; this result provides a cautionary example for studies aimed at testing malaria interventions or identifying new malaria-protective genes

    Calculations of Neutron Reflectivity in the eV Energy Range from Mirrors made of Heavy Nuclei with Neutron-Nucleus Resonances

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    We evaluate the reflectivity of neutron mirrors composed of certain heavy nuclei which possess strong neutron-nucleus resonances in the eV energy range. We show that the reflectivity of such a mirror for some nuclei can in principle be high enough near energies corresponding to compound neutron-nucleus resonances to be of interest for certain scientific applications in non-destructive evaluation of subsurface material composition and in the theory of neutron optics beyond the kinematic limit.Comment: 18 pages, 5 figures, 1 tabl

    Estrogenic Compounds Downstream from Three Small Cities in Eastern Nebraska: Occurrence and Biological Effect

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    Recent studies have detected estrogenic compounds in surface waters in North America and Europe. Furthermore, the presence of estrogenic compounds in surface waters has been attributed, in some cases, to the discharge of wastewater treatment plant (WWTP) effluent. The primary objective of the current study was to determine if WWTP effluent contributes estrogens to the surface waters of Nebraska. A second objective of this study was to determine if estrogens were found in concentrations sufficient enough to manifest feminizing effects on fish. These objectives were satisfied by deploying polar organic chemical integrative samplers (POCIS) and caged fathead minnows at eight field sites. Deployment sites included: three reference sites (Pawnee Creek, the Little Blue River, and the Middle Loup River), two sites upstream of the WWTPs at Grand Island and Columbus, and three sites downstream of the WWTPs at Grand Island, Columbus, and Hastings. Following the seven day deployments, POCIS extracts were analyzed for estrone, 17β-estradiol, estriol and 17α-ethinylestradiol using liquid chromatography tandem mass spectrometry (LC/MS/MS). 17β-estradiol was detected in POCIS from six of the eight field sites with the greatest quantities recovered in POCIS deployed downstream from the Grand Island and Hastings WWTPs. Estrone was detected only in the POCIS deployed downstream from the Grand Island and Hastings WWTPs. Estrogenic effects were detected in caged minnows analyzed for the hepatic mRNA expression of two estrogen- responsive genes, vitellogenin (vg1) and estrogen receptor α (ERα). Fish deployed at the site where the greatest quantities of estrogens were recovered (Hastings) had significantly higher expression of both vg1 and ERα than fish deployed at any of the other sites. These results confirm that WWTP effluent contributes biologically significant levels of estrogens to Nebraska surface waters

    L2 Writing Practice: Game Enjoyment as a Key to Engagement

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    Evolution of magnetic polarons and spin-carrier interactions through the metal-insulator transition in Eu1x_{1-x}Gdx_{x}O

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    Raman scattering studies as functions of temperature, magnetic field, and Gd-substitution are used to investigate the evolution of magnetic polarons and spin-carrier interactions through the metal-insulator transition in Eu1x_{1-x}Gdx_{x}O. These studies reveal a greater richness of phase behavior than have been previously observed using transport measurements: a spin-fluctuation-dominated paramagnetic (PM) phase regime for T >> T^{*} >> TC_{C}, a two-phase regime for T << T^{*} in which magnetic polarons develop and coexist with a remnant of the PM phase, and an inhomogeneous ferromagnetic phase regime for T << TC_{C}
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