The effect of pre-existing malnutrition on pediatric burn mortality in a sub-Saharan African burn unit

Introduction Nutritional status predicts burn outcomes in the developed world, but its effect on burn mortality in the developing world has not been widely studied. In sub Saharan Africa, burn is primarily a disease of children, and the majority of children in sub-Saharan Africa are malnourished. We therefore sought to determine the prevalence and effect of malnutrition on burn mortality at our institution. Methods This is a retrospective review of children aged 0–5, with anthropomorphic measurements available, who were admitted to our burn unit from July 2011 to May 2016. Age-adjusted Z scores were calculated for height, weight, weight for height, and mid-upper arm circumference (MUAC). Following bivariate analysis, we used logistic regression to construct a fully adjusted model of predictors of mortality. Results Of the 1357 admitted patients, 839 (61.2%) were aged 0–5. Of those, 512 (62.9%) had one or more anthropomorphic measurements available, and were included in the analysis. 54% were male, and the median age was 28 months. The median TBSA was 15%, with a majority of burns caused by scalds (77%). Mortality was 16%. Average Z-score for any of the indicators of malnutrition was −1.45 ± 1.66. TBSA (OR: 1.08, 95% CI: 1.06, 1.11), decreasing Z-score (OR: 1.19, 95% CI: 1.00, 1.41), and flame burn (OR: 2.51, 95% CI: 1.40, 4.49) were associated with an increase in mortality. Conclusion Preexisting malnutrition in burn patients in sub-Saharan Africa increases odds of mortality after controlling for significant covariates. Survival of burn patients in this region will not reach that of the developed world until a strategy of aggressive nutritional support is implemented in this population

Pre-burn malnutrition increases operative mortality in burn patients who undergo early excision and grafting in a sub-Saharan African burn unit

Introduction: In the developed world, pre-existing malnutrition in the burn population influences operative outcomes. However, studies on pre-existing malnutrition and operative outcomes of burn patients in the developing world are lacking. We therefore sought to characterize the burn injury outcomes following operative intervention based on nutritional status. Methods: This is a retrospective review of operative patients admitted to our burn unit from July 2011 to May 2016. Age-adjusted Z scores were calculated for height, weight, weight for height, and mid-upper arm circumference (MUAC). Following bivariate analysis, we constructed a fully adjusted logistic regression model of significant predictors of post-operative mortality, both overall and for specific age categories. Results: Of the 1356 admitted patients, 393 received operative intervention (29%). Of those, 205 (52.2%) were male, and the median age was 6 years (3, 25), with 265 patients (67%) aged ≤16 years. The median TBSA was 15.4% (10%–25%) and open flames caused the majority of burns (64%), though in children under 5, scalds were the predominant cause of burn (52.2%). Overall mortality was 14.5% (57 patients) and ranged from 9.09% for patients aged 6–16, to 33.3% for adults ≥50 years. Increased time from injury to operative intervention was protective (OR: 0.90, 95% CI: 0.83, 0.99). In post-operative patients with z-scores, increasing %TBSA burned (OR: 1.11, 95% CI: 1.05, 1.17) and increasing malnutrition (OR: 1.46, 95% CI: 1.03, 1.91) predicted death in the adjusted model. Conclusion: Poor nutrition is an important risk factor for post-operative mortality in burned patients in resource-poor settings. Screening for malnutrition and designing effective interventions to optimize nutritional status may improve surgical outcomes in LMIC burn patients

Pre-burn malnutrition increases operative mortality in burn patients who undergo early excision and grafting in a sub-Saharan African burn unit: methodological issues

Dear Editor in chief, Drs. Ashrafi-Asgarabad and Safiri raise several questions about the methodology we employed in our article. Thank you for this opportunity to respond to their letter

Deep Sand Site, Pratt Loamy Fine Sand Range on the Barby Ranch

Photograph of a deep sand site, Pratt loamy fine sand range on Barby ranch. The back of the photograph proclaims, "Deep sand site, Pratt loamy fine sand. Sec. 8-2-27. Barby Ranch.

Loamy Prairie Site

Photograph of a Loamy Prairie Site, Carey Silt loam. The back of the photograph proclaims, "Loamy Prairie Site, Carey Silt loam. Sec. 14-4-22. Logan Gregg C. R. planting in 1957, 3 years old. Little bluestem, sideoats grama, Indian grass, and bluestem and blue grama. 1.52 lbs. PLS seeded per acre.