275 research outputs found

    Magnetic field dependence of the energy of negatively charged excitons in semiconductor quantum wells

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    A variational calculation of the spin-singlet and spin-triplet state of a negatively charged exciton (trion) confined to a single quantum well and in the presence of a perpendicular magnetic field is presented. We calculated the probability density and the pair correlation function of the singlet and triplet trion states. The dependence of the energy levels and of the binding energy on the well width and on the magnetic field strength was investigated. We compared our results with the available experimental data on GaAs/AlGaAs quantum wells and find that in the low magnetic field region (B<18 T) the observed transition are those of the singlet and the dark triplet trion (with angular momentum Lz=1L_z=-1), while for high magnetic fields (B>25 T) the dark trion becomes optically inactive and possibly a transition to a bright triplet trion (angular momentum Lz=0L_z=0) state is observed.Comment: 9 pages, 10 figures submitted to Phys. Rev.

    Proteomics Analysis and Protein Expression during Sporozoite Excystation of Cryptosporidium parvum (Coccidia, Apicomplexa)

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    Cryptosporidiosis, caused by coccidian parasites of the genus Cryptosporidium, is a major cause of human gastrointestinal infections and poses a significant health risk especially to immunocompromised patients. Despite intensive efforts for more than 20 years, there is currently no effective drug treatment against these protozoa. This study examined the zoonotic species Cryptosporidium parvum at two important stages of its life cycle: the non-excysted (transmissive) and excysted (infective) forms. To increase our understanding of the molecular basis of sporozoite excystation, LC-MS/MS coupling with a stable isotope N-terminal labeling strategy using iTRAQ (TM) reagents was used on soluble fractions of both non-excysted and excysted sporozoites, i.e. sporozoites both inside and outside oocysts were examined. Sporozoites are the infective stage that penetrates small intestinal enterocytes. Also to increase our knowledge of the C. parvum proteome, shotgun sequencing was performed on insoluble fractions from both non-excysted and excysted sporozoites. In total 303 C. parvum proteins were identified, 56 of which, hitherto described as being only hypothetical proteins, are expressed in both excysted and non-excysted sporozoites. Importantly we demonstrated that the expression of 26 proteins increases significantly during excystation. These excystation-induced proteins included ribosomal proteins, metabolic enzymes, and heat shock proteins. Interestingly three Apicomplexa-specific proteins and five Cryptosporidium-specific proteins augmented in excysted invasive sporozoites. These eight proteins represent promising targets for developing vaccines or chemotherapies that could block parasite entry into host cells

    Histopathological and immunohistochemical evaluation of cellular response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch for tendon repair

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    We investigated endogenous tissue response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch intended for tendon repair. A sheep tendon injury model characterised by a natural history of consistent failure of healing was chosen to assess the biological potential of woven and aligned electrospun fibres to induce a reparative response. Patches were implanted into 8 female adult English Mule sheep. Significant infiltration of tendon fibroblasts was observed within the electrospun component of the patch but not within the woven component. The cellular infiltrate into the electrospun fibres was accompanied by an extensive network of new blood vessel formation. Tendon fibroblasts were the most abundant scaffold-populating cell type. CD45+, CD4+ and CD14+ cells were also present, with few foreign body giant cells. There were no local or systemic signs of excessive inflammation with normal hematology and serology for inflammatory markers three months after scaffold implantation. In conclusion, we demonstrate that an endogenous healing response can be safely induced in tendon by means of biophysical cues using a woven and electrospun patch

    Spin-orbit coupling effect on quantum Hall ferromagnets with vanishing Zeeman energy

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    We present the phase diagram of a ferromagnetic quantum Hall effect liquid in a narrow quantum well with vanishing single-particle Zeeman splitting, ϵZ\epsilon_{{\rm Z}} and pronounced spin-orbit coupling. Upon decreasing ϵZ\epsilon_{{\rm Z}}, the spin-polarization field of a liquid takes, first, the easy-axis configuration, followed by the formation of a helical state, which affects the transport and NMR properties of a liquid and the form of topological defects in it. The analysis is extended over high odd integer filling factors.Comment: This revised version takes into account easy-axis terms in the energy and offers a corrected phase diagram of the ferromagnetic QHE liquid. Analysis is extended over higher filling factor

    Parallel Magnetic Field Induced Transition in Transport in the Dilute Two-Dimensional Hole System in GaAs

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    A magnetic field applied parallel to the two-dimensional hole system in the GaAs/AlGaAs heterostructure, which is metallic in the absence of an external magnetic field, can drive the system into insulating at a finite field through a well defined transition. The value of resistivity at the transition is found to depend strongly on density

    Fine motor difficulties: the need for advocating for the role of occupational therapy in schools

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    Background: Fine motor difficulties can impact on the academic, social and emotional development of a student. Aim: The aims of this paper are to: (i) investigate the need for support to students experiencing fine motor&nbsp; difficulties from the perspective of their classroom teachers, and (ii) report on the level of knowledge teachers have in regard to the role of occupational therapists in supporting students with fine motor difficulties.&nbsp; Methods: Fifteen teachers from a stratified random sample of public schools within two regions of Victoria, Australia, were interviewed in this qualitative, grounded theory investigation. Results: Results showed that the current level of support for students with fine motor difficulties is inadequate. Conclusion: Occupational therapists in Victoria need to advocate their role in developing the fine motor skills of students at both an organisational and an individual level in order to increase the access of students with fine motor difficulties to occupational therapy services. <br /

    Optical manipulation of nuclear spin by a two-dimensional electron gas

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    Conduction electrons are used to optically polarize, detect and manipulate nuclear spin in a (110) GaAs quantum well. Using optical Larmor magnetometry, we find that nuclear spin can be polarized along or against the applied magnetic field, depending on field polarity and tilting of the sample with respect to the optical pump beam. Periodic optical excitation of the quantum-confined electron spin reveals a complete spectrum of optically-induced and quadrupolar-split nuclear resonances, as well as evidence for delta m = 2 transitions.Comment: 13 pages, 4 figures. Submitted for publicatio

    Negatively Charged Excitons and Photoluminescence in Asymmetric Quantum Well

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    We study photoluminescence (PL) of charged excitons (XX^-) in narrow asymmetric quantum wells in high magnetic fields B. The binding of all XX^- states strongly depends on the separation δ\delta of electron and hole layers. The most sensitive is the ``bright'' singlet, whose binding energy decreases quickly with increasing δ\delta even at relatively small B. As a result, the value of B at which the singlet--triplet crossing occurs in the XX^- spectrum also depends on δ\delta and decreases from 35 T in a symmetric 10 nm GaAs well to 16 T for δ=0.5\delta=0.5 nm. Since the critical values of δ\delta at which different XX^- states unbind are surprisingly small compared to the well width, the observation of strongly bound XX^- states in an experimental PL spectrum implies virtually no layer displacement in the sample. This casts doubt on the interpretation of PL spectra of heterojunctions in terms of XX^- recombination
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