4,521 research outputs found
In Defense of Truth: Skepticism, Morality, and The Matrix
The Matrix exposes us to the uncomfortable worries of philosophical skepticism in an especially compelling way. However, with a bit more reflection, we can see why we need not share the skeptic’s doubts about the existence of the world. Such doubts are appropriate only in the very special context of the philosophical seminar. When we return to normal life we see immediately that they are groundless. Furthermore, we see also the drastic mistake that Cypher commits in turning his back upon reality and re-entering the matrix. Not only does reason compel us to admit the existence of the external world, it also requires us to face this world, to build for ourselves meaningful lives within it, and to engage, as adults, in the serious business of living
Polarized quark distributions in nuclear matter
We compute the polarized quark distribution function of a bound nucleon. The
Chiral Quark-Soliton model provides the quark and antiquark substructure of the
nucleon embedded in nuclear matter. Nuclear effects cause significant
modifications to the polarized distributions including an enhancement of the
axial coupling constant.Comment: 5 Pages, 2 Postscript figures, Version to be published in Phys. Rev.
Chiral solitons in nuclei: Electromagnetic form factors
We calculate the electromagnetic form factors of a bound proton. The Chiral
Quark-Soliton model provides the quark and antiquark substructure of the
proton, which is embedded in nuclear matter. This procedure yields significant
modifications of the form factors in the nuclear environment. The sea quarks
are almost completely unaffected, and serve to mitigate the valence quark
effect. In particular, the ratio of the isoscalar electric to the isovector
magnetic form factor decreases by 20% at Q^2=1 GeV^2 at nuclear density, and we
do not see a strong enhancement of the magnetic moment.Comment: 13 pages, 6 figures, Added references and a clearer connection to
experimen
EVOLUTION OF SALMON LIFE HISTORIES 1
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72527/1/j.0014-3820.2004.tb01745.x.pd
Material and Structural Aspects of Bone in Osteogenesis Imperfecta
Bone fragility is a fundamental problem in individuals with osteogenesis imperfecta (OI). The mechanisms behind this fragility, however, are not yet well understood. Multiple factors appear to contribute to the increased fracture risk in OI. At the structural level, bone mass deficiency can result in increased stress levels within bones. The underlying mineral and collagen abnormalities that define OI are also believed to result in compromised material-level properties. The variability of collagen biochemical irregularities causing OI and the corresponding heterogeneity of disease severity result in abnormalities that are not easily generalized within the OI population.
The aims of this chapter are to introduce basic mechanical notions pertaining to the strength of structures and materials, and to present a synthesis of existing literature regarding the mechanical properties of bones in OI
Macroscopic Anisotropic Bone Material Properties in Children with Severe \u3cem\u3eOsteogenesis imperfecta\u3c/em\u3e
Children with severe osteogenesis imperfecta(OI) typically experience numerous fractures and progressive skeletal deformities over their lifetime. Recent studies proposed finite element models to assess fracture risk and guide clinicians in determining appropriate intervention in children with OI, but lack of appropriate material property inputs remains a challenge. This study aimed to characterize macroscopic anisotropic cortical bone material properties and investigate relationships with bone density measures in children with severe OI. Specimens were obtained from tibial or femoral shafts of nine children with severe OI and five controls. The specimens were cut into beams, characterized in bending, and imaged by synchrotron radiation X-ray micro-computed tomography. Longitudinal modulus of elasticity, yield strength, and bending strength were 32–65% lower in the OI group (p \u3c 0.001). Yield strain did not differ between groups (p ≥ 0.197). In both groups, modulus and strength were lower in the transverse direction (p ≤ 0.009), but anisotropy was less pronounced in the OI group. Intracortical vascular porosity was almost six times higher in the OI group (p \u3c 0.001), but no differences were observed in osteocyte lacunar porosity between the groups (p = 0.086). Volumetric bone mineral density was lower in the OI group (p \u3c 0.001), but volumetric tissue mineral density was not (p = 0.770). Longitudinal OI bone modulus and strength were correlated with volumetric bone mineral density (p ≤ 0.024) but not volumetric tissue mineral density (p ≥ 0.099). Results indicate that cortical bone in children with severe OI yields at the same strain as normal bone, and that their decreased bone material strength is associated with reduced volumetric bone mineral density. These results will enable the advancement of fracture risk assessment capability in children with severe OI
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