12,585 research outputs found
Seeking the Real Adam Smith and Milton Friedman
In this paper we will analyze the relationship between free market principles and ethics through an exploration of how too many business managers often approach the ideas of Adam Smith and Milton Friedman. In doing so, we aim to provide a thoughtful foundation for future discussions of how we ought to navigate this intersection. We briefly examine questions such as: What is the relationship between the âbestâ economy in terms of efficiency and the common good for society? Is pursuing oneâs individual economic advantage the same as promoting the general interest? As we analyze and discuss these questions, specifically in the context of Smith and Friedman, we also make some alternative normative assertions, grounded in social welfare, about adopting a broader societal perspective for the purpose of business
Police crime: a constitutional perspective.
It is held that the police officer is liable at criminal and civil law the same as the citizen;
given constitutional expression in the common law office of constable. Yet, in the
execution of their duty police officers are prone to committing a range of criminal
offences - assault, false imprisonment, perverting the course of justice - defined in this
thesis as police crimes. Statistical analysis reveals that police officers are rarely
prosecuted for these offences, suggesting that criminal liability is an illusion, and civil
proceedings have become an increasingly popular remedy for police wrongdoing.
This thesis holds that ss.48 and 49 of the Police Act 1964 played a prominent part in
undermining the police officer's accountability to the law. This was achieved under s.48
by removing the police officer's personal responsibility for his wrongdoing at civil law,
and introduction of a vicarious liability rule. And, under s.49, by definition of reports of
alleged criminal offences committed by police officers as complaints, and codification of
a separate criminal procedure. Since the 1964 Act, statute and case law on police
wrongdoing have caused further damage to the constitutional position by emphasising the
internal police complaint and disciplinary processes and devaluing issues of liability.
It is argued that there is a conflict between the ancient office of constable and the recently
developed doctrine of constabulary independence, and it is proposed that a 'balance
model' accurately reflects the constitutional position of the police. This thesis examines
recent developments at common law alongside the statutory trend, including intended
reform of the complaint and discipline processes, and concludes that the integrity of the
constitutional position has been seriously damaged. It is proposed that the police officer
is no longer accountable to the law for his wrongdoing in like manner as the citizen, and
the office of constable survives as a constitutional fiction
Molecular gas in nearby powerful radio galaxies
We report the detection of CO(1-0) and CO(2-1) emission from the central
region of nearby 3CR radio galaxies (z 0.03). Out of 21 galaxies, 8 have
been detected in, at least, one of the two CO transitions. The total molecular
gas content is below 10 \msun. Their individual CO emission exhibit, for 5
cases, a double-horned line profile that is characteristic of an inclined
rotating disk with a central depression at the rising part of its rotation
curve. The inferred disk or ring distributions of the molecular gas is
consistent with the observed presence of dust disks or rings detected optically
in the cores of the galaxies. We reason that if their gas originates from the
mergers of two gas-rich disk galaxies, as has been invoked to explain the
molecular gas in other radio galaxies, then these galaxies must have merged a
long time ago (few Gyr or more) but their remnant elliptical galaxies only
recently (last 10 years or less) become active radio galaxies. Instead, we
argue the the cannibalism of gas-rich galaxies provide a simpler explanation
for the origin of molecular gas in the elliptical hosts of radio galaxies (Lim
et al. 2000). Given the transient nature of their observed disturbances, these
galaxies probably become active in radio soon after the accretion event when
sufficient molecular gas agglomerates in their nuclei.Comment: 6 pages, including 2 figures,in "QSO Hosts and Their Environments",
ed. I. Marquez, in pres
Recommended from our members
Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P
Recent research has proposed a pathway in which sensory neurons expressing the capsaicin activated ion channel TRPV1 are required for histamine-induced itch and subsequent scratching behavior. We examined histamine-induced itch in the African naked mole-rat (Heterocephalus glaber) and found that although naked mole-rats display innate scratching behavior, histamine was unable to evoke increased scratching as is observed in most mouse strains. Using calcium imaging, we examined the histamine sensitivity of naked mole-rat dorsal root ganglia (DRG) neurons and identified a population of small diameter neurons activated by histamine, the majority of which are also capsaicinsensitive. This suggested that naked mole-rat sensory neurons are activated by histamine, but that spinal dorsal horn processing of sensory information is not the same as in other rodents. We have previously shown that naked mole-rats naturally lack substance P (SP) in cutaneous C-fibers, but that the neurokinin-1 receptor is expressed in the superficial spinal cord. This led us to investigate if SP deficiency plays a role in the lack of histamine-induced scratching in this species. After intrathecal administration of SP into the spinal cord we observed robust scratching behavior in response to histamine injection. Our data therefore support a model in which TRPV1-expressing sensory neurons are important for histamine-induced itch. In addition, we demonstrate a requirement for active, SP-induced post-synaptic drive to enable histamine sensitive afferents to drive itch-related behavior in the naked mole-rat. These results illustrate that it is altered dorsal horn connectivity of nociceptors that underlies the lack of itch and pain-related behavior in the naked mole-rat.This work was supported by the Alexander von Humboldt Foundation (EStJS)
and NSF grant 0744979 (TJP)
Optical response of nanostructured metal/dielectric composites and multilayers
The homogeneous optical response in conducting nanostructured layers, and in insulating layers containing dense arrays of self assembled conducting nanoparticles separated by organic linkers, is examined experimentally through their effective complex indices (n*, k*). Classical effective medium models, modified to account for the 3-phase nanostructure, are shown to explain (n*, k*) in dense particulate systems but not inhomogeneous layers with macroscopic conductance for which a different approach to homogenisation is discussed, (n*, k*) data on thin granular metal films, thin mesoporous gold, and on thin metal layers containing ordered arrays of voids, is linked to properties of the surface plasmon states which span the nanostructured film. Coupling between evanescent waves at either surface counterbalanced by electron scattering losses must be considered. Virtual bound states for resonant photons result, with the associated transit delay leading to a large rise in n* in many nanostructures. Overcoating n-Ag with alumina is shown to alter (n*, k*) through its impact on the SP coupling. In contrast to classical optical homogenisation, effective indices depend on film thickness. Supporting high resolution SEM images are presented
Experience with cochlear implants in Greenlanders with profound hearing loss living in Greenland
Objective. Cochlear implant (CI) treatment was introduced to the world in the 1980s and has become a routine treatment for congenital or acquired severe-to-profound hearing loss. CI treatment requires access to a highly skilled team of ear, nose and throat specialists, audiologists and speech-language pathologists for evaluation, surgery and rehabilitation. In particular, children treated with CI are in need of long-term post-operative auditory training and other follow-up support. Design. The study is retrospective with updated information on present performance. Results. Since 2001, a total of 11 Greenlandic patients living in Greenland have been treated with CI, 7 children and 4 adults. Of these children, 4 use oral communication only and are full-time CI-users, 2 with full-time use of CI are still in progress with use of oral communication, and 1 has not acquired oral language yet, but has started auditory and speech training. Six children attend mainstream public school while one child is in kindergarten. Of the adults, only 1 has achieved good speech perception with full-time use of CI while 3 do not use the CI. Discussion. From an epidemiological point of view, approximately 1–3 children below 6 years are in need of a CI every second year in Greenland often due to sequelae from meningitis, which may cause postinfectious deafness. Screening of new-borns for hearing has been started in Greenland establishing the basis for early diagnosis of congenital hearing impairment and subsequent intervention. The logistics and lack of availability of speech therapists in Greenland hampers possibilities for optimal language and speech therapy of CI patients in Greenland. This study aims at describing the results of CI treatment in Greenlanders and the outcome of the CI operations along with the auditory and speech/language outcomes. Finally, we present a suggestion for the future CI treatment and recommendations for an increased effort in the treatment and rehabilitation of implanted patients in Greenland
Investigating white matter fibre density and morphology using fixel-based analysis
Voxel-based analysis of diffusion MRI data is increasingly popular. However, most white matter voxels contain contributions from multiple fibre populations (often referred to as crossing fibres), and therefore voxel-averaged quantitative measures (e.g. fractional anisotropy) are not fibre-specific and have poor interpretability. Using higher-order diffusion models, parameters related to fibre density can be extracted for individual fibre populations within each voxel (âfixelsâ), and recent advances in statistics enable the multi-subject analysis of such data. However, investigating within-voxel microscopic fibre density alone does not account for macroscopic differences in the white matter morphology (e.g. the calibre of a fibre bundle). In this work, we introduce a novel method to investigate the latter, which we call fixel-based morphometry (FBM). To obtain a more complete measure related to the total number of white matter axons, information from both within-voxel microscopic fibre density and macroscopic morphology must be combined. We therefore present the FBM method as an integral piece within a comprehensive fixel-based analysis framework to investigate measures of fibre density, fibre-bundle morphology (cross-section), and a combined measure of fibre density and cross-section. We performed simulations to demonstrate the proposed measures using various transformations of a numerical fibre bundle phantom. Finally, we provide an example of such an analysis by comparing a clinical patient group to a healthy control group, which demonstrates that all three measures provide distinct and complementary information. By capturing information from both sources, the combined fibre density and cross-section measure is likely to be more sensitive to certain pathologies and more directly interpretable
Development of high temperature, radiation hard detectors based on diamond
© 2016 Single crystal CVD diamond has many desirable properties compared to current, well developed, detector materials; exceptional radiation, chemical and physical hardness, chemical inertness, low Z (close to human tissue, good for dosimetry), wide bandgap and an intrinsic pathway to fast neutron detection through the 12C(n,α)9Be reaction. However effective exploitation of these properties requires development of a suitable metallisation scheme to give stable contacts for high temperature applications. To best utilise available processing techniques to optimise sensor response through geometry and conversion media configurations, a reliable model is required. This must assess the performance in terms of spectral response and overall efficiency as a function of detector and converter geometry. The same is also required for proper interpretation of experimental data. Sensors have been fabricated with varying metallisation schemes indented to permit high temperature operation; Present test results indicate that viable fabrication schemes for high temperature contacts have been developed and present modelling results, supported by preliminary data from partners indicate simulations provide a useful representation of response
Demonstration of astrocytes in cultured amniotic fluid cells of three cases with neural-tube defect
We have investigated the origin of rapidly adhering (RA) cells in three cases of neural tube defects (two anencephali, one encephalocele). We were able to demonstrate the presence of glial fibrillary acidic (GFA) protein in variable percentages (4â80%) of RA cells cultured for 4â6 days by use of indirect immunofluorescence with GFA antiserum. Cells cultured from amniotic fluids of normal pregnancies and fetal fibroblasts were completely GFA protein negative. GFA protein is well established as a highly specific marker for astrocytes. Demonstration of astrocytes may prove to be a criterion of high diagnostic value for neural tube defects. The percentage of astrocytes decreased with increasing culture time, while the percentage of fibronectin positive cells increased both in amniotic fluid cell cultures from neural tube defects and normal pregnancies
Experiences of enhanced recovery after surgery in general gynaecology patients: An interpretative phenomenological analysis.
There is little qualitative research exploring non-cancer gynaecology patientsâ experiences of enhanced recovery after surgery (ERAS) protocols. Seven women participated in audio-recorded interviews, discussing their experiences of enhanced recovery after surgery for gynaecological surgery. Data were transcribed and analysed using interpretative phenomenological analysis. Three themes were identified: meeting informational needs, taking control of pain, and mobilising when feeling fragile. Control emerged as a key element throughout the themes and was supported by provision of factual information. While participants were generally satisfied with their experience, topics such as concerns about analgesic use, the informal role of staff in mobilisation, and the expressed desire for more experiential information for participants require further research.N/
- âŠ