40 research outputs found

    Hormonal Changes as a Potential Cause for Monthly Fluid Status Variation as Indicated by Intrathoracic Impedance

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    Early detection of decompensated heart failure enables clinicians to tailor medical therapy to individual patient needs. The utility of transthoracic impedance assessment in the early diagnosis of volume overload has been documented in the literature. We describe the case of a young woman without congestive heart failure who was noted to have cyclical variations of transthoracic impedances that correlated with her menstrual cycle and discuss other factors that may confound proper diagnosis of volume overload in patients with implantable cardioverter-defibrillators

    The Role of Nonlinear Dynamics in Cardiac Arrhythmia Control

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    The field of nonlinear dynamics has made important contributions towards a mechanistic understanding of cardiac arrhythmias. In recent years, many of these advancements have been in the area of arrhythmia control. In this paper, we will review the analytical, modeling, and experimental nonlinear dynamical arrhythmia control literature. We will focus on stimulation and pharmacological techniques that have been developed, and in some cases used in experiments, to control reentrant rhythms (including spiral and scroll waves) and fibrillation. Although such approaches currently have practical limitations, they offer hope that nonlinear dynamical control techniques will be clinically useful in the coming years. Christini et al. 3 1 Introduction In recent years, cardiac electrophysiology has evolved from a discipline that was of interest primarily to physicians and physiologists to one that has caught the attention of physicists, mathematicians, and engineers. Such scientists have come to..
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