Deconstructing the Standards

The purpose of this Professional Learning Module (PLM) is to improve teacher understanding of academic standard deconstruction. We created this professional learning module to assist educators in better understanding how to deconstruct standards. In this PLM, you will find information about: 1.The need for deconstruction 2.The deconstruction process 3. Identifying learning Targets 4. Using a graphic organizer 5. Common assessments aligned to standards We hope that both educators and district-level personnel will find this PLM instrumental in the training process of deconstructing standards. In unpacking, repacking, and organizing standards, teachers will develop a better understanding of what the standards are explicitly stating what isrequired of students academically. The deconstructing process will also give educators the opportunity to create quality assessments for students in improving mastery across content areas. View professional learning module.https://digitalcommons.gardner-webb.edu/improve/1035/thumbnail.jp

CAROL - Robotic Catalyst Removal

PresentationWorleyParsons has developed the industry’s first commercial robot for catalyst unloading from refinery and petrochemical vessels. The development of CAROLTM (Catalyst Removal Amphirol) responds to increasingly stringent requirements to reduce human risk in inert confined-space entry. It is the culmination of a three-year development effort from conception and design to prototyping and testing and represents a potential game-changer in the industry. The number of fixed-bed catalytic vessels in the global refining and petrochemical industry is estimated to exceed 58,000. Based on current technology a rough estimate of the number of worker days of risk exposure due to confined-space entry during catalyst unloading exceeds 10,000 days per year. Current practices for catalyst removal from each of these vessels pose a risk to safety and/or the environment. CAROL provides an alternative option that minimizes risk to workers. CAROL is a simple, one-of-a kind machine that has been demonstrated to achieve vacuum catalyst removal without the placement of workers inside the vessel. A review of operating characteristics in a single bed test vessel is provided. Additionally, two case studies from commercial field trials are presented. This paper showcases the challenges associated with current catalyst removal techniques, and the inherent safety advantages that CAROL has shown. The presentation includes video of the test vehicle operating characteristics and discussion on industry acceptance progress and preliminary test results

Ancient Egypt 1922 Part 4

Part 4 of the 1922 Ancient Egypt books. Contents include the Shellal mosaic, Old World cubit in America, the Constantinople obelisk, the rise of prices in Egypt, dualism in African religions, and Egyptian mathematics.https://knowledge.e.southern.edu/kweeks_coll/1021/thumbnail.jp

Amino acid neurotransmitters and dopamine in brain and pituitary of the goldfish: involvement in the regulation of gonadotropin secretion

Abstract: An isocratic high-performance liquid chromatographic technique was developed to measure levels of yaminobutyric acid (GABA), glutamate, and taurine in the brain and pituitary of goldfish. Accuracy of this procedure for quantification of these compounds was established by evaluating anesthetic and postmortem effects and by selectively manipulating GABA concentrations by intraperitoneal administration of the glutamic acid decarboxylase (GAD) inhibitor 3-mercaptopropionic acid or the GABA transaminase inhibitor y-vinyl GABA. The technique provided a simple, rapid, and reliable method for evaluating the concentrations of these amino acids without the use of complex gradient chromatographic systems. To investigate the relationship between neurotransmitter amino acids and the control of pituitary secretion of gonadotropin, the effects of injection of taurine, GABA, or monosodium glutamate on GABA, glutamate, taurine, and, in some instances, monoamine concentrations in the brain and pituitary were evaluated and related to serum gonadotropin levels. Injection of taurine caused an elevation in serum gonadotropin concentrations. In addition, injection of the taurine precursor hypotaurine but not the taurine cataboiite isetheonic acid elevated serum gonadotropin levels. Intracerebroventricular injection of either GABA or taurine also elevated serum gonadotropin concentrations. Pretreatment of recrudescent fish with a-methyl-p-tyrosine reduced pituitary dopamine concentrations and also potentiated the serum gonadotropin response to taurine. Injection of monosodium glutamate caused an increase of glutamate content in the pituitary at 24 h; this was followed by a decrease at 72 h after administration. Pituitary GABA, taurine, and dopamine concentrations underwent a transient depletion after monosodium glutamate administration, and this was associated with an elevation of serum gonadotropin content. The increase in serum gonadotropin concentrations in response to a gonadotropin-releasing hormone analogue was potentiated by pretreatment with monosodium glutamate. This article demonstrates that procedures causing elevation in GABA and taurine concentrations stimulate gonadotropin release in a teleost fish. Key Words: y-Aminobutyric acidGlutamate-TaurineDopamine-Gonadotropin-Goldfish. Sloley B. D. et al. Amino acid neurotransmitters and dopamine in brain and pituitary of the goldfish: Involvement in the regulation of gonadotropin secretion. J. Neurochem. 58,2254Neurochem. 58, -2262

Towards a matrix mechanics framework for dynamic protein network

Protein–protein interaction networks are currently visualized by software generated interaction webs based upon static experimental data. Current state is limited to static, mostly non-compartmental network and non time resolved protein interactions. A satisfactory mathematical foundation for particle interactions within a viscous liquid state (situation within the cytoplasm) does not exist nor do current computer programs enable building dynamic interaction networks for time resolved interactions. Building mathematical foundation for intracellular protein interactions can be achieved in two increments (a) trigger and capture the dynamic molecular changes for a select subset of proteins using several model systems and high throughput time resolved proteomics and, (b) use this information to build the mathematical foundation and computational algorithm for a compartmentalized and dynamic protein interaction network. Such a foundation is expected to provide benefit in at least two spheres: (a) understanding physiology enabling explanation of phenomenon such as incomplete penetrance in genetic disorders and (b) enabling several fold increase in biopharmaceutical production using impure starting materials

Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study

Over the last decade, Asian ginseng (Panax ginseng) has been shown to improve aspects of human cognitive function. American ginseng (Panax quinquefolius) has a distinct ginsenoside profile from P. ginseng, promising cognitive enhancing properties in preclinical studies and benefits processes linked to human cognition. The availability of a highly standardised extract of P. quinquefolius (Cereboost (TM)) led us to evaluate its neurocognitive properties in humans for the first time. This randomised, double-blind, placebo-controlled, crossover trial (N = 32, healthy young adults) assessed the acute mood, neurocognitive and glycaemic effects of three doses (100, 200 400 mg) of Cereboost (TM) (P. quinquefolius standardised to 10.65% ginsenosides). Participants' mood, cognitive function and blood glucose were measured 1, 3 and 6 h following administration. There was a significant improvement of working memory (WM) performance associated with P. quinquefolius. Corsi block performance was improved by all doses at all testing times. There were differential effects of all doses on other WM tasks which were maintained across the testing day. Choice reaction time accuracy and 'calmness' were significantly improved by 100 mg. There were no changes in blood glucose levels. This preliminary study has identified robust working memory enhancement following administration of American ginseng. These effects are distinct from those of Asian ginseng and suggest that psychopharmacological properties depend critically on ginsenoside profiles. These results have ramifications for the psychopharmacology of herbal extracts and merit further study using different dosing regimens and in populations where cognition is fragile

Possible effects of heptocellular carcinoma on diabetes mellitus

A 10 year old, spayed female Keeshond presented to the Cornell Soft Tissue Surgery service for removal of a large hepatic mass. 4 ½ year history of diabetes mellitus with recent difficulty in regulating was believed to be associated with the hepatic mass. The mass was successfully removed and submitted for histopathology. The mass was diagnosed as hepatocellular carcinoma. After removal of the mass the insulin needed to regulate blood glucose levels decreased. Several theories have been researched about the relationship between hepatocellular carcinoma and blood glucose levels including the production of insulin-growth factor II, disruption of the liver affecting liver function, overproduction of cortisol, and other theories will be discussed in this paper