Clinical significance of predictive factors in development and treatment of carotid restenosis in patients after eversion endarterectomy.

Uvod: Karotidna endarterektomija je vrlo pouzdana metoda za lečenje simptomatske i asimptomatske visoko-stepene karotidne stenoze. Karotidna restenoza predstavlja ponovno suženje karotidne arterije koje nastaje kao rezultat neointimalne hiperplazije u ranom postoperativnom periodu (unutar 36 meseci) ili rekurentnih aterosklerotskih lezija u kasnijem toku. Nekoliko studija je pokazalo da je povišena koncentracija Creaktivnog proteina (CRP) nezavistan prognostički faktor budućih kardioloških ishemičnih događaja, ali je malo raspoloživih podataka koji govore o povezanosti karotidne ateroskleroze i serumske koncentracije hs-CRP i drugih proteina akutne faze inflamacije. Ciljevi: Cilj naše studije bio je da ispitamo uticaj preoperativno i neposredno post operativno (48h) povišenih vrednosti sistemskih markera inflamacije („high sensitive“ C-reaktivni protein (hs-CRP), C3 komplement i fibrinogen), njihovih oscilacia i uticaj na nastanak karotidne restenoze nakon everzione endarterektomije tokom praćenja. Takođe smo analizarali uticaj infamatorne komponente i strukture karotidnog plaka na nastanak karotidne restenoze kao i uticaj svih faktora rizika i drugih udruženih oboljenja. Poslednji cilj bio je da uporedimo rezultate perkutane angioplastike i ponovnog hirurškog lečenja pacijenata sa karotidnom restenozom uz evaluaciju prediktivnih faktora koji mogu imati uticaja na konačni ishod oba modaliteta lečenja. Materijal i metode: Ispitivanjem obuhvaćeno je 300 pacijenata kojima je na Klinici za Vaskularnu hirurgiju Instituta za kardiovaskularne bolesti „Dedinje“ učinjena everziona karotidna endarterektomija od 1.marta do 1. avgusta 2010. godine. Analizirana je serumska koncentracija „high-sensitive“ C-reaktivnog proteina (hs- CRP), fibrinogena i C3 komplementa na dan operacije neposredno pre enadarterektomije, 48 časova nakon endarterektomije, kao i na redovnim kontrolnim pregledima nakon 1 meseca, 6 meseci, godinu dana i dve godine...Objective: Carotid endarterectomy is known as very reliable procedure for symptomatic and asymptomatic carotid stenosis treatment. Carotid restenosis represents recurrent stenosis that occurs as a result of neointimal hyperplasia in the early postoperative period (within 36 months) or recurrent atherosclerotic lesions in the following period. Several studies have shown that increased C-reactive protein (CRP) values is independent prognostic factor of future cardiological ischemic events, but there is a few studies that describe connection between CRP serum concentration, carotid atherosclerosis and other acute inflammatory phasec proteins. Aims: The aim of our study was to examine influence of increased values of markers of systemic inflammation (high sensitivity C-reactive protein (hs-CRP), C3 complement and fibrinogen) taken just before and after the surgery, its oscillations and its mutual impact on carotid restenosis development after eversion endarterectomy. We have also analyzed the impact of inflammatory component and structure of the carotid plaque on carotid restenosis development as well as influence of all risk factors and other comorbidities. The last aim was to compare the outcome of percutaneous angioplasty and “redo” surgical treatment in patients with carotid restenosis with evaluation of predictive factors influencing the final outcome in both treatment modalities. Methodology: In the presented study, 300 patients were included in whom eversion carotid endarterectomy was performed from 1st march till 1st august 2010. on the Vascular surgery Clinic, “Dedinje” cardiovascular Institute. We have analyzed serum concentration of hs-CRP, fibrinogen and C3 complement taken just before the surgery (06h), 48h after the surgery and on the regular check-ups after 1 month, 6 months, one year and two years. In then second part of the presented study we have retrospectively compared the outcomes of endovascular and “redo” surgical treatment of patients with carotid restenosis in the period from 2002. till 2012..

MONITORING OF FLIGHT PHENOLOGY OF RASPBERRY CANE MIDGE RESSELIELLA THEOBALDI BARNES (DIPTERA: CECIDOMYIIDAE) BY PHEROMONE TRAPS IN WESTERN SERBIA

The flight phenology of the raspberry cane midge Resseliella (Thomasiniana) theobaldi Barnes (Diptera, Cecidomyiidae) was monitored over three successive years (2006-2008) in a raspberry orchard of the Fruit Research Institute Čačak, at the 'Zdravljak' site. This was the first time that large white delta traps baited with the raspberry cane midge sex pheromone were used. No insecticides were used during the monitoring period. Throughout the period, over three growing seasons, the midge presence was detected from April-May to September-October. During the three years, there were variations in the numbers of midges caught per trap, as well as those in the total numbers of midges trapped across years and peak numbers per trap. The highest total number (2,419) of midges during the season and the highest number of midges per trap in a sample (729) were recorded in 2007. The earliest maximum catch per trap (729) occurred on 11 May, 2007

Influence of the Ringer's solution on wear of vacuum mixed poly(methyl methacrylate) bone cement in reciprocating sliding contact with AISI 316L stainless steel

This paper presents microstructural properties and damage behaviour of a vacuum mixed poly(methyl metacrylate) (PMMA) bone cement, during the sliding contact with AISI 316L stainless steel, under micro-loads. Influence of the Ringer's solution on the wear was analysed in comparison to dry contact. The variation of load did not produce any significant change of the wear factor while the increase in the sliding speed induced significant increases in the wear factor, more pronounced in the case of dry sliding. The obtained wear factors were in average higher for the sliding in Ringer's solution than those obtained under dry conditions. Significant fragmentation of the worn tracks, of irregular shapes with broken edges, was observed, slightly more pronounced for the dry contact. Many cavities and voids were formed on the wear track surface, but they did not extend into the bulk material. Higher loads produced more uniform and less fragmented wear tracks. Abrasive, adhesive wear and plastic deformation grooves were observed, as well as fatigue and erosive wear. Fatigue cracks developed in the direction normal to sliding. Network of fine craze cracks was exhibited on the surface of wear tracks, especially pronounced in the case of dry sliding. These results are important since they contribute to understanding the sites of crack initiation, and development mechanisms on the surface of PMMA bone cements, also including synergistic effects of physiological environments pertaining to the non-steady crack and craze behaviour and crack pattern development in PMMA

Algorithm for defining quality of base material for repair welding

The paper shows the comparison of different methodologies for defining the quality of base material due for repair welding as one of the basic and initial problems during the repair of damaged parts or machine equipment. The quality of a previously damaged repaired machine part depends on successfully defined quality of base material. In addition to the analysis of discussed methodologies, the paper also provides an algorithm for decision flow between different methodologies. The overall analysis is performed in cooperation with employees in HBIS GROUP company Serbia Iron & Steel, Smederevo, as result of experiences and cases during maintaining of the facility. The proposed algorithm is designed in order to predominantly help engineers in the decision making with the goal to establish and create an appropriate repair welding procedure so to achieve required integrity of the machine/structure

Algorithm for defining quality of base material for repair welding

The paper shows the comparison of different methodologies for defining the quality of base material due for repair welding as one of the basic and initial problems during the repair of damaged parts or machine equipment. The quality of a previously damaged repaired machine part depends on successfully defined quality of base material. In addition to the analysis of discussed methodologies, the paper also provides an algorithm for decision flow between different methodologies. The overall analysis is performed in cooperation with employees in HBIS GROUP company Serbia Iron & Steel, Smederevo, as result of experiences and cases during maintaining of the facility. The proposed algorithm is designed in order to predominantly help engineers in the decision making with the goal to establish and create an appropriate repair welding procedure so to achieve required integrity of the machine/structure

Overview and analysis of stress and strained steel chimney's state

U radu je opisana metodologija pregleda industrijskih dimnjaka, kao i analiza naponsko - deformacionog stanja na osnovu obrađenih rezultata izvršenih merenja. Debljina čeličnog plašta dimnjaka u TO "Višnjička banja" je određivana ultrazvučnim postupkom u 204 merne tačke. Izvršeni vizuelni pregled je ukazao na veoma loše stanje dimnjaka. Dimnjak je, radi dobijanja osnove za proračun savremenim numeričkim metodama, modeliran pomoću CAD softvera. Numerička analiza naponsko - deformacionog stanja je izvršena za opterećenja od sopstvene težine, vetra i zemljotresa. .Industrial chimney inspection methodology is described in this paper, and stress and strain analysis is done by result processing of the measurements. Thickness of flue - stack's steel shell at thermo facility "Visnjicka Banja" is determined by means of ultrasound in 204 points. Visual inspection of chimney has indicated high level of damage. Chimney was modeled in CAD software as basis for numerical analysis by contemporary methods. Numerical analysis of stress and strain chimney's state is done for gravity load, and loads caused by wind and earthquake.

Overview and analysis of stress and strained steel chimney's state

U radu je opisana metodologija pregleda industrijskih dimnjaka, kao i analiza naponsko - deformacionog stanja na osnovu obrađenih rezultata izvršenih merenja. Debljina čeličnog plašta dimnjaka u TO "Višnjička banja" je određivana ultrazvučnim postupkom u 204 merne tačke. Izvršeni vizuelni pregled je ukazao na veoma loše stanje dimnjaka. Dimnjak je, radi dobijanja osnove za proračun savremenim numeričkim metodama, modeliran pomoću CAD softvera. Numerička analiza naponsko - deformacionog stanja je izvršena za opterećenja od sopstvene težine, vetra i zemljotresa. .Industrial chimney inspection methodology is described in this paper, and stress and strain analysis is done by result processing of the measurements. Thickness of flue - stack's steel shell at thermo facility "Visnjicka Banja" is determined by means of ultrasound in 204 points. Visual inspection of chimney has indicated high level of damage. Chimney was modeled in CAD software as basis for numerical analysis by contemporary methods. Numerical analysis of stress and strain chimney's state is done for gravity load, and loads caused by wind and earthquake.

Aktuelna istraživanja u oblasti zaštite voćaka

The study results of new economically important causal agents of diseases and fruit pests were presented. Over 20 types of Erwinia amylovora have been isolated and identified on pome fruits. The most frequent peach, apricot, and plum diseases are the following: brown fruit rot, drying of small branches and canker. The importance of virus free planting material and resistant cultivars was emphasized. Using the nested PCR and PCR-RFLP methods showed the presence of Phytophthora fragarie var. rubi on three raspberry cultivars. Cecidial raspberry drying is one of the most economically harmful disease. Bacterial raspberry blight was described for the first time in Serbia. Acarology studies are directed towards the following: mechanisms of plant resistance, resistance of mites towards acaricides, efficacy of biopesticides and development of molecular methods for the faster identification of species. The increase in the population of Lymatria dispar, Cacopsylla pruni and Carcopidae was assessed in orchards.Prikazani su rezultati istraživanja novih bolesti i štetočina voćaka sa posebnim osvrtom na: molekularnu detekciju patogena, Pseudomonas syringae na koštičavom voću, sojeve Erwinia amylovora na jabučastim voćkama, prouzrokovače mrke truleži (Monilinia spp.) i rak rana (Leucostoma spp.) na koštičavim vrstama voćaka, molekularne metode za utvrđivanje prisustva Phytophthora fragariae var. rubi na malini, cecidoizno sušenje maline, prouzrokovača bakteriozne plamenjače maline (Pseudomonas syringae pv. syringae), akarološka istraživanja, kao i na porast brojnosti Lymantria dispar, Cacopsylla pruni i cikada penuša (Cercopidae), zaštitu voćaka u organskoj proizvodnji

Photon management in semiconductor infrared photodetectors: diffractive and plasmonic antireflective structures

Due to their high specific detectivities and large response speeds, photodetectors based on narrow-bandgap semiconductors like indium-antimonide and mercury cadmium telluride are indispensable for mid- and far-infrared wavelength ranges. Their response is directly proportional to the infrared radiation flux introduced to the detector active area. Thus various photon management techniques are of crucial importance for enhancing their performance. This work analyzes the use of subwavelength nanophotonic structures with antireflective properties. It considers surface-based diffractive optical structure that can be produced by micromachining and nanofabrication. The first part of the consideration is dedicated to all-dielectric subwavelength arrays with 1D and 2D periodicity, which effectively behave as impedance-matching structures with graded effective refractive index. The consideration is then expanded to metal-dielectric structures, especially those belonging to the class of the so-called plasmonic ultra-absorbers. Technologies available in Serbia are then investigated technologies for the fabrication of the dielectric and metaldielectric subwavelength antireflective structures for the infrared, including isotropic and anisotropic etching of surface reliefs and ultrathin-film deposition techniques. It is concluded that diffractive dielectric and plasmonic structures offer a novel degree of freedom in optimization of infrared semiconductor photodetectors