Recurrent Dermatofibrosarcoma Protuberans of the Shoulder with Rare Distant Abdominal Metastasis detected by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

N

Tenosynovial giant cell tumor with extensive myxoid change: A rare variant of a common tumor

Tenosynovial giant cell tumor is a common tumor of synovial origin that usually occurs between the ages of 30 and 50 years. It is classified into localized and diffuse types based on the presence of a capsule around the lesion. Histologically, it is characterized by scattered large epithelioid cells with eosinophilic cytoplasm and eccentric nuclei, histiocytoid cells, multinucleated osteoclast-like giant cells, and varying amounts of hemosiderin deposition. Prominent myxoid stroma is a very rare finding in this tumor. We report the case of a 35-year-old woman with tenosynovial giant cell tumor, whereby otherwise typical cells are set in a predominant loose myxoid stroma. This morphology is important to recognize, as it can closely mimic other soft tissue tumors with a predominant myxoid matrix

Proximal Ulna: A Rare Location for Solitary Intraosseous Hemangioma

Intraosseous hemangiomas are rare, benign bone tumors usually affecting the bones of the axial skeleton. Its incidence in the long bones is extremely rare. We report a 19-year-old boy with solitary intraosseous hemangioma of the proximal ulna. Radiographs and computed tomography images showed a well-defined osteolytic lesion involving the right proximal ulna. Magnetic resonance imaging showed intermediate signal intensity on T1-weighted images and increased signal intensity on T2-weighted images with internal trabeculae and peripheral post-contrast enhancement. Postcurettage histologic diagnosis of intraosseous hemangioma was made

CT imaging of malignant metastatic hemangiopericytoma of the parotid gland with histopathological correlation

We report an extremely rare case of malignant hemangiopericytoma (HPC) of the parotid gland and its metastatic spread to lung, liver, and skeletal muscle. Computed tomography (CT) imaging, histopathological and immunohistochemical methods were employed to study the features of malignant HPC and its metastases. CT imaging was helpful to determine the exact location, involvement of adjacent structures and vascularity, as well as evaluating pulmonary, hepatic, peritoneal, and muscular metastases. Immunohistochemical and histopatholgical features of the primary tumor as well as the metastases were consistent with the diagnosis of malignant HPC

Recurrent Dermatofibrosarcoma Protuberans of the Shoulder with Rare Distant Abdominal Metastasis detected by Fluorodeoxyglucose-Positron Emission Tomography - Computed Tomography ( FDG-PET / CT )

N

ZC3H7B-BCOR high-grade endometrial stromal sarcoma with osseous metaplasia: Unique feature in a recently defined entity

High-grade endometrial stromal sarcoma harboring ZC3H7B-BCOR fusion is a newly defined entity in gynecologic pathology featuring a set of distinct histopathological and molecular features. It is morphologically characterized by atypical ovoid to spindle cells with a fascicular architecture, usually embedded within a myxoid stroma. Unlike high-grade endometrial stromal sarcoma associated with YWHAE-NUTM2 fusion, the neoplastic cells are consistently immunoreactive to CD10. It may be confused with myxoid leiomyosarcoma and carcinosarcoma, although the expression of myoid and epithelial markers is absent or very limited. Osseous metaplasia has not been previously described in this tumor. The presence of osseous metaplasia may raise the differential diagnosis of ossifying fibromyxoid tumor, which is also associated with ZC3H7B-BCOR fusion. The clinical prognosis is poor with disease progression in all cases described thus far. In this report, we describe a 52-year-old Singaporean woman of Chinese descent with ZC3H7B-BCOR high-grade endometrial stromal sarcoma containing focal osseous metaplasia