Study of the associations between polymorphic markers rs1800629 TNFα, rs909253 Ltα, rs767455 TNFR1, rs1061624 TNFR2 and the development of type 2 diabetes = Изучение ассоциаций полиморфных маркеров генов факторов некроза опухоли и их рецепторов rs1800629 TNFα, rs909253 Ltα, rs767455 TNFR1, rs1061624 TNFR2 с формированием сахарного диабета 2 типа

To study the association between polymorphic genetic markers, tumor necrosis factors and their receptors (rs 1800629 TNFα, rs 909253 Ltα, rs 767455 TNFR1, rs 1061624 TNFR2) and the development of type 2 diabetes (T2D) among the population of the Central Black Earth Region of Russi

Genes Involved in Vascular Homeostasis are responsible for alterations in erythrocyte membrane proteins in patients with essential hypertension

Alterations in structural and functional properties of the cell membrane may represent diseaseassociated intermediate phenotypes reflecting the mechanisms of essential hypertension. The study was designed to assess the effects of polymorphisms in genes associated with EH on the variation of erythrocyte membrane proteins in hypertensive patient

The contribution of CYP2C gene subfamily involved in epoxygenase pathway of arachidonic acids metabolism to hypertension susceptibility in Russian population

The present study was designed to investigate whether common single-nucleotide polymorphisms (SNP) of CYP2C gene subfamily such as CYP2C8 (rs7909236 and rs1934953), CYP2C9 (rs9332242), and CYP2C19 (rs4244285) are associated with susceptibility to EH in Russian populatio

Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population

Epoxyeicosatrienoic acids (EETs) are important vasoactive products of arachidonic acid metabolism with a wide range of biological actions in the cardiovascular system. The present study investigated whether single nucleotide polymorphisms of genes coding cytochrome P450 2C subfamily, enzymes involved in biosynthesis of EETs, are associated with the risk of coronary heart diseas

The contribution of MTHFR C677T polymorphism to peripheral artery disease in diabetic patients

The aim of this study was to investigate the association between functional polymorphism C677T (rs1801133) of methylenetetrahydrofolate reductase (MTHFR) gene for and risk of peripheral artery disease in diabetes patient

Pharmacogenetic study of lipid-lowering therapy with rosuvastatin in coronary artery disease patients

Polymorphic genes involved in the regulation of lipid metabolism may be responsible for interindividual differences in efficiency of hypolipidaemic therapy. In the present prospective and randomised study, we investigated the efficacy of rosuvastatin (10 mg/day) in lipid-lowering therapy in 62 patients with coronary artery disease (CAD) possessing different genotypes of lipoprotein lipase (LPL) gen

Association of Interleukins Genes Polymorphic Markers with Speed of CGN’s Advance

The authors investigated associations of polymorphism of interleukins genes with nephritic survivance of the ill with chronic glomerulonephritis among 238 patients with CGN and 241 control group individual

Chemokines Genetic Variants are Associated with Parameters of Humoral Immunity of Patients with Chronic Glomerulonephritis

The authors researched associations of chemokines genes polymorphisms with parameters of humoral immunity of 238 patients with chronic glomerulonephritis and 462 individuals of a control grou

Studying the Impact of the genetic polymorphisms of chemokines on the arterial pressure level and kidney function in patient with the chronic glomerulonephritis

It has been established that the genetic marker А I-TAC (rs 4512021) is the risk factor for genesis of the severe arterial hypertension at the chronic glomerulonephritis (OR=1,65) and the genotypes АА and AG I-TAC are the risk factors of depression of the kidney functio

Using the elements of traditional culture in the teaching process from the perspectiveof ethnopedagogy and ethnology

The presented study aims to briefly present the possibilities of using and implementing elements of traditional culture in the teaching processat primary and secondary schools in Slovakia. It points out all the aspects and factors that enter the educational process when using these element