43 research outputs found
Sorting Visualizer: A Visual Journey Through Sorting Algorithms
This paper, which is based on the importance of sorting algorithms, will carefully compare the features of various algorithms, beginning with their work effectiveness, algorithm execution, introductory concepts, sorting styles, and other aspects, and make conclusions in order to create more effective sorting algorithms. Searching techniques and sorting algorithms are not the same. Sorting is placing the provided list in a predetermined order, which can be either ascending or descending, whereas searching is predicated on the possibility of finding a specific item in the list. Only a section of the data is sorted, and the piece of data that's actually used to establish the sorted order is the key. The maturity of this data is being compared. Depending on the kind of data structure, there are several algorithms for doing the same set of duties and other conditioning, and each has pros and cons of its own. Numerous sorting algorithms have been analysed grounded on space and time complexity. The aim of this relative study is to identify the most effective sorting algorithms or styles. This relative study grounded on the same analysis allows the user to select the applicable sorting algorithm for the given situation
An In-Depth Evaluation of Recommendation Systems: Methods, Challenges, and Solutions
Recommendation systems (RS) play a vital role in the digital landscape, in shaping user experiences across various platforms. It delves into the origins and key characteristics of Content-Based Filtering and Collaborative Filtering, backed by empirical analysis to underscore their practical significance. It will go through the intricate development stages of RS, spanning from data investigation to prediction methodologies, and tackles challenges such as the cold-start problem. RS is categorized into three main types: collaborative filtering, content-based filtering, and hybrid recommendation systems, highlighting their potential synergy in enhancing recommendation accuracy result and breadth. These insights lay the groundwork for subsequent, which explore evaluation techniques, seminal research, dataset analysis, and experimental findings, concluding with reflections and avenues for future research to advance the field of recommendation systems
Drowsiness Detection System in Real Time Based on Behavioral Characteristics of Driver using Machine Learning Approach
The process of determining if a person, generally a driver, is becoming sleepy or drowsy while performing a task such as driving is known as drowsiness detection. It is a necessary system for detecting and alerting drivers to their tiredness, which might impair their driving ability and lead to accidents. The project aims to create a reliable and efficient system capable of real-time detection of drowsiness using OpenCV, Dlib, and facial landmark detection technologies. The project's results show that the sleepiness detection method can accurately and precisely identify tiredness in real time. The technology is less intrusive and more economical than conventional sleepiness detection techniques. The system is based on a 68 facial landmark detector, which is a highly trained and effective detector capable of recognizing human face points. The detector aids in assessing whether the driver's eyes are closed or open. The system analyses the data collected by the detector using machine learning methods to discover patterns associated with drowsiness. When drowsiness is detected, the system incorporates a warning mechanism, such as an alarm or a vibration in the steering wheel, to notify the driver. A variety of studies with different drivers and driving conditions were used to evaluate the performance of the real-time driver drowsiness detection system. The results show that the technology can detect tiredness properly and deliver timely warnings to the driver. This method can assist in preventing drowsy driving incidents, enhancing road safety, and saving lives. The results indicated that the algorithm had an average accuracy rate of 94% for identifying tiredness in drivers
Multiple Disease Prediction System using Machine Learning
Machine learning advancements have spurred a revolution in healthcare by making it possible to create prediction models for early disease diagnosis. This report introduces the Multiple Disease Prediction System (MDPS), a state-of-the-art approach that uses machine learning to forecast the likelihood of several diseases based on patient data, including medical history, lifestyle, and demographics. The MDPS addresses the growing difficulties in healthcare by focusing on the early detection of multiple diseases. Some of its crucial components include data preparation, feature selection, model training and disease Detection. Despite advantages like early detection and cost savings, dealing with data privacy, model interpretability, and continuous improvements is essential for MDPS's ethical and efficient usage in healthcare. As a result, MDPS has a significant potential to enhance public health and minimize the difficulties associated with chronic illnesses
Cellular electrophysiologic responses of isolated neonatal and adult cardiac fibers to d-sotalol
AbstractThe short-term cellular electrophysiologic actions of d-sotalol on isolated neonatal and adult canine ventricular myocardium and Purkinje fibers were evaluated using standard microelectrode techniques. d-Sotalol, 10−6to 10−4M, had no effects on action potential amplitude, maximal diastolic potential or action potential upstroke velocity (Vmax) in any neonatal or adult preparation. In five adult myocardial preparations, d-sotalol produced concentration-dependent increases in action potential duration at 50% (APD50) and 90% (APD90) repolarization and effective refractory period. In six neonatal myocardial preparations, d-sotalol produced a biphasic response; APD50, APD90and effective refractory period decreased at 10−6and 10−5M. At 10−4M, these values increased significantly but to a lesser extent compared with values in adults.In seven adult Purkinje fibers, d-Sotalol significantly increased APD50, APD90and effective refractory period in a concentration-dependent manner. All six neonatal Purkinje fibers responded in a biphasic manner, with values for APD50, APD90and effective refractory period being less than control at 10−6Mand near control values at 10−5M. At 10−4M, these variables were significantly increased, but to a lesser extent than in audlt preparations. Our data confirm the typical class III effects of d-sotalol in adult cardiac tissues. The shortening of repolarization and refractoriness at lower drug concentrations in developing cardiac tissues may relate to age-dependent differences in cellular ionic function and basic electrophysiology
Electrophysiologic effects of a new anitarrhythmic agent, recainam, on isolated canine and rabbit myocardial fibers
AbstractRecainam (Wy 42,362) is a new antiarrhythmic agent undergoing clinical evaluation, but its electrophysiologic effects in cardiac muscle are poorly defined. With microelectrode techniques, its profile in isolated preparations of dog and rabbit hearts was determined using drug concentrations of 10 to 300 μM. Recainam induced a concentration and frequency-dependent decrease in the maximal rate of rise of ihe phase 0 of the action potential (Vmax), action potential amplitude and overshoot potential, with little or no change in the effective refractory period except in Purkinje fibers, in which it was markedly reduced. At a 300 μMconcentration, Vmaxwas reduced 51% (p < 0.001) in ventricular muscle and 44% (p < 0.001) in atrial muscle, with no change in action potential duration or effective refractory period. At the same drug concentration in Purkinje fibers, Vmaxwas decreased by 41% (p < 0.01), action potential duration at 90% repolarization by 36% (p < 0.01) and effective refractory period by 34% (p < 0.01). Recainam had no significant effect on the sinoatrial node, but it depressed phase 4 depolarization in isoproterenol-induced automaticity in Purkinje fibers. The drug had no effect on slow channel potentials induced by high concentrations of potassium and isoproterenol.The data indicate that the electrophysiologic profile of recainam in isolated cardiac muscle is consistent with the overall effects of class IC agents without having an effect on the slow calcium channel. Its major action is to depress Vmax, with little effect on refractoriness. As in the case of other class IC compounds, the differential effects of recainam on the action potential duration in ventricular muscle and Purkinje fibers may predispose to the drug's proarrhythmic actions by accentuating heterogeneity in refractoriness in the heart
Electrophysiological effects of MS-551, a new class III agent: comparison with dl-sotalol in dogs. J Pharmacol Exp Ther 285:687–694
ABSTRACT MS-551 is a newly synthesized, nonspecific K ϩ channel blocker. To elucidate its electrophysiological and potential proarrhythmic effects relative to those of dl-sotalol in vivo, serial changes in ECGs, endocardial and epicardial monophasic action potential durations, and left and right ventricular pressures were measured simultaneously in pentobarbital-anesthetized open-chest dogs. Complete heart block was produced by the injection of 37% formaldehyde into the atrioventricular node. Intravenous administration of MS-551 produced prolongation of action potential duration at 90% repolarization time (APD 90 ) immediately after the beginning of infusion and reached plateau at 10 min. MS-551 (1 mg/kg) caused 73 Ϯ 8% increase in APD 90 and 28 Ϯ 5% increase in QT c at basic cycle length of 700 msec. The maximal prolongation of APD 90 induced by 1 mg/kg MS-551 was 39% greater than that by the same dose of sotalol (P Ͻ .01). The dose-response curve of prolongation of ventricular effective refractory period produced by MS-551 was shifted significantly to the left compared with that induced by sotalol. The EC 50 was 0.5 Ϯ 0.1 mg/kg and 1.2 Ϯ 0.2 mg/kg for MS-551 and sotalol, respectively (P Ͻ .05). When 0.5 mg/kg MS-551 doses were used, no ventricular arrhythmia was induced by stimulation at 200-msec basic cycle length. When 1.5 mg/kg sotalol was administered, 5 of 15 developed torsade de pointes, 2 of 15 developed ventricular fibrillation and 5 of 15 developed sustained ventricular tachycardia. The idioventricular rates and left ventricular pressures were reduced significantly by sotalol, not by MS-551. In conclusion, MS-551 is a potent class III antiarrhythmic agent that selectively prolongs repolarization in the ventricular myocardium and appears to be devoid of autonomic effects. Dose for dose, it is more potent in prolonging the APD 90 and the right ventricular effective refractory period possibly with a lower tendency for the development of proarrhythmia in a canine heart-block model