Urban Flood Prediction through GIS-Based Dual-Coupled Hydraulic Models

Propagation of pluvial floods in urban areas, occurring with return time periods of few years, can be well solved using dual models accounting for the mutual relationship between the water level in the streets and the discharges inside the sewer pipes. The extended WEC-flood model (EWEC), based on the use of unstructured triangular meshes and a diffusive formulation of the momentum equations in both the 2D and the 1D lower domains, is presented along with its novelty, limits, and advantages. The model is then applied to a small computational domain in the Palermo area, where only some 'hard' data given by one rain gauge has been used for calibration and validation, along with other 'soft' data like yes/no surcharge observations and water depths available from photos and interviews. Model input data are mainly geometrical parameters, and calibration parameters are restricted only to average Manning coefficients. In the test case a very good validation has been obtained of three historical events using the EWEC model, with only one average Manning coefficient calibrated using other two historical events

Reverse remodeling in Dilated Cardiomyopathy: Insights and future perspectives

Dilated Cardiomyopathy (DCM) has been classically considered a progressive disease of the heart muscle that inexorably progresses towards refractory heart failure, ventricular arrhythmias and heart transplant. However, the prognosis of DCM has significantly improved in the past few years, mostly as the result of successful therapy-induced reverse remodeling. Reverse remodeling is a complex process that involves not only the left ventricle, but also many other cardiac structures and it is now recognized both as a measure of therapeutic effectiveness and as an important prognostic tool. Nevertheless, several aspects of reverse remodeling remain unclear, including the best timing for its quantification, its predictors and its interaction with individual genetic backgrounds. In this review, we summarize our current understanding of reverse remodeling in patients with DCM and provide practical recommendations for the clinical management of this challenging patient population

Myocarditis evolving in cardiomyopathy: When genetics and offending causes work together

Myocarditis is an infectious-inflammatory disease often superimposed to individual genetic background which could favour or inhibit its progression into a chronic heart muscle disorder (most often dilated cardiomyopathy, rarely arrhythmogenic, or right-sided cardiomyopathy). Post-myocarditis cardiomyopathy is likely caused by a complex interaction between the viral infection and an individual predisposition. Some viruses are able to highlight a clinical phenotype replicating a model similar to the genetically determined conditions, while other can affect the resolution or the progressive remodelling of the left ventricle after the infectious process. The identification of specific individual genetic backgrounds, or genes favouring the progression of the disease, are important future research goals for precision medicine aiming at a specific and individualized treatment for patients affected with myocarditis

A paradigm of extreme rainfall pluvial floods in complex urban areas: The flood event of 15 July 2020 in Palermo (Italy)

In the last few years, some regions of the Mediterranean area have witnessed a progressive increase in extreme events, such as urban and flash floods, as a response to the increasingly frequent and severe extreme rainfall events, which are often exacerbated by the ever-growing urbanization. In such a context, the urban drainage systems may not be sufficient to convey the rainwater, thus increasing the risk deriving from the occurrence of such events. This study focuses on a particularly intense urban flood that occurred in Palermo (Italy) on 15 July 2020; it represents a typical pluvial flood due to extreme rainfall on a complex urban area that many cities have experienced in recent years, especially in the Mediterranean region. A conceptual hydrological model and a 2D hydraulic model, particularly suitable for simulations in a very complex urban context, have been used to simulate the event. Results have been qualitatively validated by means of crowdsourced information and satellite images. The experience of Palermo, which has highlighted the urgent need for a shift in the way stormwater in urban settlements is managed, can be assumed to be a paradigm for modeling pluvial floods in complex urban areas under extreme rainfall conditions. Although the approaches and the related policies cannot be identical for all cities, the modeling framework used here to assess the impacts of the event under study and some conclusive remarks could be easily transferred to other, different urban contexts

A New Cross-Flow Type Turbine for Ultra-Low Head in Streams and Channels

In the last few decades, hydropower production has been moving toward a new paradigm of low and diffused power density production of energy with small and mini-hydro plants, which usually do not require significant water storage. In the case of nominal power lower than 20 kW and ultra-low head H (H < 5 m), Archimedes screw or Kaplan type turbines are usually chosen due to their efficiency, which is higher than 0.85. A new cross-flow type turbine called Ultra-low Power Recovery System (UL-PRS) is proposed and its geometry and design criteria are validated in a wide range of operating conditions through 2D numerical analysis computed using the ANSYS Fluent solver. The new proposed solution is much simpler than the previously mentioned competitors; its outlet flow has a horizontal direction and attains similar efficiency. The costs of the UL-PRS turbine are compared with the costs of one Kaplan and one cross-flow turbine (CFT) in the case study of the main water treatment plant of the city of Palermo in Italy. In this case, the UL-PRS efficiency is estimated using a URANS 3D numerical analysis computed with the CFX solver