The management of acute venous thromboembolism in clinical practice. Results from the European PREFER in VTE Registry

Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in Europe. Data from real-world registries are necessary, as clinical trials do not represent the full spectrum of VTE patients seen in clinical practice. We aimed to document the epidemiology, management and outcomes of VTE using data from a large, observational database. PREFER in VTE was an international, non-interventional disease registry conducted between January 2013 and July 2015 in primary and secondary care across seven European countries. Consecutive patients with acute VTE were documented and followed up over 12 months. PREFER in VTE included 3,455 patients with a mean age of 60.8 ± 17.0 years. Overall, 53.0 % were male. The majority of patients were assessed in the hospital setting as inpatients or outpatients (78.5 %). The diagnosis was deep-vein thrombosis (DVT) in 59.5 % and pulmonary embolism (PE) in 40.5 %. The most common comorbidities were the various types of cardiovascular disease (excluding hypertension; 45.5 %), hypertension (42.3 %) and dyslipidaemia (21.1 %). Following the index VTE, a large proportion of patients received initial therapy with heparin (73.2 %), almost half received a vitamin K antagonist (48.7 %) and nearly a quarter received a DOAC (24.5 %). Almost a quarter of all presentations were for recurrent VTE, with >80 % of previous episodes having occurred more than 12 months prior to baseline. In conclusion, PREFER in VTE has provided contemporary insights into VTE patients and their real-world management, including their baseline characteristics, risk factors, disease history, symptoms and signs, initial therapy and outcomes

Thermodynamic properties of adsorbed water in zeolites and comparison with clay minerals

The process of water vapour adsorption is reversible in the case of zeolites because of their rigid microporous structure, but irreversible in the case of clay minerals because of swelling that takes place in their sheet structure. The Polanyi-Dubinin theory applicable for zeolites is also used for clay minerals in the region of homogeneous hydration and thermodynamic functions are calculated from the Dubinin-Astakhov plot.Simonot-Grange Marie-Hélène. Thermodynamic properties of adsorbed water in zeolites and comparison with clay minerals. In: Proceedings of the 9th international Clay Conference, Strasbourg, 1989. Vol III : Geochemistry of clays. Nuclear waste disposal. Strasbourg : Institut de Géologie – Université Louis-Pasteur, 1990. pp. 25-33. (Sciences Géologiques. Mémoire, 87

Apport de la cinétique à la connaissance des machines thermiques à affinité. I – Cinétique de l’évolution du système liquide-vapeur-zéolithe pendant le processus adsorption-évaporation ou étape de production de froid

Une approche de l’étude cinétique des machines frigorifiques mettant en jeu le système liquide-vapeur-zéolithe montre comment a partir de lois semi-empiriques et de relations qui en découlent, il est possible de déterminer les conditions qui favorisent l’établissement d’un régime quasi stationnaire d’évaporation

Thermodynamic properties of adsorbed water in zeolites and comparison with clay minerals

The process of water vapour adsorption is reversible in the case of zeolites because of their rigid microporous structure, but irreversible in the case of clay minerals because of swelling that takes place in their sheet structure. The Polanyi-Dubinin theory applicable for zeolites is also used for clay minerals in the region of homogeneous hydration and thermodynamic functions are calculated from the Dubinin-Astakhov plot.Simonot-Grange Marie-Hélène. Thermodynamic properties of adsorbed water in zeolites and comparison with clay minerals. In: Proceedings of the 9th international Clay Conference, Strasbourg, 1989. Vol III : Geochemistry of clays. Nuclear waste disposal. Strasbourg : Institut de Géologie – Université Louis-Pasteur, 1990. pp. 25-33. (Sciences Géologiques. Mémoire, 87

Hydration thermodynamic functions of hectorite and nontronite from experimental isotherms and the Polanyi-Dubinin method

The integral and differential enthalpies, entropies and free enthalpies of hydration and dehydration of hectorites and nontronites are calculated from the Polanyi-Dubinin theory in the ranges of relative pressure from 0.2 to 0.99 and temperature from 15 to 110 degrees Celsius. Intraparticle swelling hysteresis at a given hydration state is characterized by the sum of the free enthalpies of hydration and dehydration.Elm'chaouri Abdellah, Simonot-Grange Marie-Hélène. Hydration thermodynamic functions of hectorite and nontronite from experimental isotherms and the Polanyi-Dubinin method. In: Proceedings of the 9th international Clay Conference, Strasbourg, 1989. Vol III : Geochemistry of clays. Nuclear waste disposal. Strasbourg : Institut de Géologie – Université Louis-Pasteur, 1990. pp. 35-43. (Sciences Géologiques. Mémoire, 87