An experimental and theoretical investigation of plane-stress fracture of 2024-T351 aluminum alloy

Plane-stress fracture behavior of precracked aluminum alloy

ICONE10-22646 AN IMPROVED MODEL FOR POSTULATING FABRICATION FLAWS IN REACTOR PRESSURE VESSELS FOR STRUCTURAL INTEGRITY EVALUATION

ABSTRACT This paper presents an improved model for postulating fabrication flaws in reactor pressure vessels (RPVs) and for the treatment of measured flaw data by probabilistic fracture mechanics (PFM) codes that are used for structural integrity evaluations. The model used to develop the current pressurized thermal shock (PTS) regulations conservatively postulated that all fabrication flaws were inner-surface breaking flaws. To reduce conservatisms and uncertainties in flaw-related inputs

Heritability of physical activity traits in Brazilian families: the Baependi Heart Study

<p>Abstract</p> <p>Background</p> <p>It is commonly recognized that physical activity has familial aggregation; however, the genetic influences on physical activity phenotypes are not well characterized. This study aimed to (1) estimate the heritability of physical activity traits in Brazilian families; and (2) investigate whether genetic and environmental variance components contribute differently to the expression of these phenotypes in males and females.</p> <p>Methods</p> <p>The sample that constitutes the Baependi Heart Study is comprised of 1,693 individuals in 95 Brazilian families. The phenotypes were self-reported in a questionnaire based on the WHO-MONICA instrument. Variance component approaches, implemented in the SOLAR (Sequential Oligogenic Linkage Analysis Routines) computer package, were applied to estimate the heritability and to evaluate the heterogeneity of variance components by gender on the studied phenotypes.</p> <p>Results</p> <p>The heritability estimates were intermediate (35%) for weekly physical activity among non-sedentary subjects (weekly PA_NS), and low (9-14%) for sedentarism, weekly physical activity (weekly PA), and level of daily physical activity (daily PA). Significant evidence for heterogeneity in variance components by gender was observed for the sedentarism and weekly PA phenotypes. No significant gender differences in genetic or environmental variance components were observed for the weekly PA_NS trait. The daily PA phenotype was predominantly influenced by environmental factors, with larger effects in males than in females.</p> <p>Conclusions</p> <p>Heritability estimates for physical activity phenotypes in this sample of the Brazilian population were significant in both males and females, and varied from low to intermediate magnitude. Significant evidence for heterogeneity in variance components by gender was observed. These data add to the knowledge of the physical activity traits in the Brazilian study population, and are concordant with the notion of significant biological determination in active behavior.</p

EVALUATION OF CONCRETE PROPERTY DATA AT ELEVATED TEMPERATURES FOR USE IN THE SAFE-CRACK COMPUTER CODE

Design and analysis of Hanford double-shell waste storage tanks has made use of the finite element computer code SAFE-CRACK as a check of the concrete portion of the tank design after cmpletion of design. Rockwell Hanford Operations, the site contractor responsible for operation of the tanks, has requested Battelle Pacific Northwest Laboratory (PNL) to evaluate the use of the Hanford concrete property data at elevated temperatures by the SAFE-CRACK code. The purpose of this investigation is to evaluate the proper use of the mathematical expressions in SAFE-CRACK to best define the physical concrete properties extrapolated from the documented concrete property data when subjected to elevated temperatures and cyclic temperature variations

Dynamic gas flow during plasma operation in TMX-U

Control of the neutral density outside of the plasma radius is essential for proper operation of the various plasma configurations in TMX-U. TMX-U excess-beam, stream-gun, gas-box, and beam-reflux gases are pumped internally in regions defined by 73/sup 0/ Ti-gettered liners and warm Ti-gettered plasma liners. The array of fast and slow ion gauges - a large TMX-U diagnostic - has been used to measure the dynamic pressure in many of the liner-defined regions on three time scales. The natural divertor action, or plasma pump effect, of mirror plasmas has been measured using the ion gauge diagnostics on a fast time scale during operation of TMX-U with ECRH start-up. Routine operation of TMX-U is enhanced by the ability to verify the effectiveness of gettering and to locate leaks using pressure data collected on the two slow time scales. A computer code, DYNAVAC 6, which treats TMX-U as a set of conductance-coupled regions with pumping and sources in each region, has been used to successfully model the overall gas dynamics during all phases of TMX-U operation

Probabilistic Fracture Mechanics Evaluation of Selected Passive Components – Technical Letter Report

This report addresses the potential application of probabilistic fracture mechanics computer codes to support the Proactive Materials Degradation Assessment (PMDA) program as a method to predict component failure probabilities. The present report describes probabilistic fracture mechanics calculations that were performed for selected components using the PRO-LOCA and PRAISE computer codes. The calculations address the failure mechanisms of stress corrosion cracking, intergranular stress corrosion cracking, and fatigue for components and operating conditions that are known to make particular components susceptible to cracking. It was demonstrated that the two codes can predict essentially the same failure probabilities if both codes start with the same fracture mechanics model and the same inputs to the model. Comparisons with field experience showed that both codes predict relatively high failure probabilities for components under operating conditions that have resulted in field failures. It was found that modeling assumptions and inputs tended to give higher calculated failure probabilities than those derived from data on field failures. Sensitivity calculations were performed to show that uncertainties in the probabilistic calculations were sufficiently large to explain the differences between predicted failure probabilities and field experience

Integration of NDE Reliability and Fracture Mechanics

The Pacific Northwest Laboratory is conducting a four-phase program for measuring and evaluating the effectiveness and reliability of in-service inspection (lSI} performed on the primary system piping welds of commercial light water reactors (LWRs). Phase I of the program is complete. A survey was made of the state of practice for ultrasonic rsr of LWR primary system piping welds. Fracture mechanics calculations were made to establish required nondestrutive testing sensitivities. In general, it was found that fatigue flaws less than 25% of wall thickness would not grow to failure within an inspection interval of 10 years. However, in some cases failure could occur considerably faster. Statistical methods for predicting and measuring the effectiveness and reliability of lSI were developed and will be applied in the &quot;Round Robin Inspections&quot; of Phase II. Methods were also developed for the production of flaws typical of those found in service. Samples fabricated by these methods wilI be used in Phase II to test inspection effectiveness and reliability. Measurements were made of the influence of flaw characteristics {i.e., roughness, tightness, and orientation) on inspection reliability. These measurernents, as well as the predictions of a statistical model for inspection reliability, indicate that current reporting and recording sensitivities are inadequate

From DNA sequence to application: possibilities and complications

The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages. This knowledge relates both to the assignments of open reading frames (ORF’s) and the function of non-coding DNA sequences. Comparison of the complete nucleotide sequences of several LAB bacteriophages has revealed that their chromosomes have a fixed, modular structure, each module having a set of genes involved in a specific phase of the bacteriophage life cycle. LAB bacteriophage genes and DNA sequences have been used for the construction of temperature-inducible gene expression systems, gene-integration systems, and bacteriophage defence systems. The function of several LAB open reading frames and transcriptional units have been identified and characterized in detail. Many of these could find practical applications, such as induced lysis of LAB to enhance cheese ripening and re-routing of carbon fluxes for the production of a specific amino acid enantiomer. More knowledge has also become available concerning the function and structure of non-coding DNA positioned at or in the vicinity of promoters. In several cases the mRNA produced from this DNA contains a transcriptional terminator-antiterminator pair, in which the antiterminator can be stabilized either by uncharged tRNA or by interaction with a regulatory protein, thus preventing formation of the terminator so that mRNA elongation can proceed. Evidence has accumulated showing that also in LAB carbon catabolite repression in LAB is mediated by specific DNA elements in the vicinity of promoters governing the transcription of catabolic operons. Although some biological barriers have yet to be solved, the vast body of scientific information presently available allows the construction of tailor-made genetically modified LAB. Today, it appears that societal constraints rather than biological hurdles impede the use of genetically modified LAB.