Seismogenic Structure Orientation and Stress Field of the Gargano Promontory (Southern Italy) From Microseismicity Analysis

Historical seismic catalogs report that the Gargano Promontory (southern Italy) was affected in the past by earthquakes with medium to high estimated magnitude. From the instrumental seismicity, it can be identified that the most energetic Apulian sequence occurred in 1995 with a main shock of MW = 5.2 followed by about 200 aftershocks with a maximum magnitude of 3.7. The most energetic earthquakes of the past are attributed to right-lateral strike-slip faults, while there is evidence that the present-day seismicity occur on thrust or thrust-strike faults. In this article, we show a detailed study on focal mechanisms and stress field obtained by micro-seismicity recorded from April 2013 until the present time in the Gargano Promontory and surrounding regions. Seismic waveforms are collected from the OTRIONS Seismic Network (OSN), from the Italian National Seismic Network (RSN), and integrated with data from the Italian National Accelerometric Network (RAN) in order to provide a robust dataset of earthquake localizations and focal mechanisms. The effect of uncertainties of the velocity model on fault plane solutions (FPS) has been also evaluated indicating the robustness of the results. The computed stress field indicates a deep compressive faulting with maximum horizontal compressive stress, SHmax, trending NW-SE. The seismicity pattern analysis indicates that the whole crust is seismically involved up to a depth of 40 km and indicates the presence of a low-angle seismogenic surface trending SW-NE and dipping SE-NW, similar to the Gargano–Dubrovnik lineament. Shallower events, along the eastern sector of the Mattinata Fault (MF), are W-E dextral strike-slip fault. Therefore, we hypothesized that the seismicity is locally facilitated by preexisting multidirectional fractures, confirmed by the heterogeneity of focal mechanisms, and explained by the different reactivation processes in opposite directions over the time, involving the Mattinata shear zon

Seismicity of the Gargano promontory (Southern Italy) after 7 years of local seismic network operation: Data release of waveforms from 2013 to 2018

The University of Bari (Italy), in cooperation with the Na- tional Institute of Geophysics and Volcanology (INGV) (Italy), has installed the OTRIONS micro-earthquake network to bet- ter understand the active tectonics of the Gargano promon- tory (Southern Italy). The OTRIONS network operates since 2013 and consists of 12 short period, 3 components, seis- mic stations located in the Apulian territory (Southern Italy). This data article releases the waveform database collected from 2013 to 2018 and describes the characteristics of the local network in the current configuration. At the end of 2018, we implemented a cloud infrastructure to make more robust the acquisition and storage system of the networ

Gargano Promontory (Italy) microseismicity (2013-2018): waveform data and earthquake catalogue

Database of the collected waveforms of microearthquakes occurred in the Gargano region (Southern Italy), recorded by the stations of the National Seismic Network (RSN-INGV) and by the Gargano seismic network (OTRIONS) in the period 2013/04/15 to 2018/08/05, and that integrates the INGV catalogue (http://cnt.rm.ingv.it/). Database of the recognized earthquakes. The University of Bari (Italy) in cooperation with the National Institute of Geophysics and Volcanology (INGV) (Italy), deployed, in 2013, the OTRIONS micro-earthquake network aiming to better understand the active tectonics of the Gargano promontory (Southern Italy). The network consists of 12 short period 3 component seismic stations located in the Apulian territory (Southern Italy). This data releases regards the waveform database collected from 2013 up to 2018. At the end of 2018, we implemented a cloud infrastructure to make more robust the acquisition and storage system of the network through a collaboration with the RECAS-Bari computing centre of the University of Bari (Italy) and of the National Institute of Nuclear Physics (Italy). From the beginning of 2019 waveform dataset and the station metadata are accessible through the European Integrated Data Archive

Tenofovir renal safety in HIV-infected patients: results from the SCOLTA project

Objective: To evaluate the prevalence and incidence of nephrotoxicity in HIV-infected patients enrolled in the SCOLTA Project tenofovir cohort and to identify possible risk factors. Design: The SCOLTA Project is a prospective, observational, multicenter study involving 25 infectious disease departments in Italy created to assess the incidence of severe adverse events in patients receiving new antiretroviral drugs. Patients: The SCOLTA Project tenofovir cohort includes a total of 754 HIV infected patients. Results: Data including grade IIeIV creatinine elevations according to ACTG scale were available in 354 patients, 237 (67%) males with a mean age of 40.1 ± 7.6 years enrolled in the SCOLTA Project tenofovir cohort. During a mean follow up of 19.5 ± 11.5 months creatinine elevations were reported in 9/354 (2.5%) patients, all males. Mean duration of tenofovir therapy at the event was 9.5 ± 5 months. The overall incidence was 1.6 (95% CI 1.5e1.7) per 100 person-years (p-y) and 0.5 (95% CI 0.4e0.6) p-y for grade III. No grade IV creatinine elevations were reported. Patients with nephrotoxicity were older and more frequently male, HCV infected, in CDC stage C and their CD4 cell count was significantly lower than those without nephrotoxicity. No significant difference was found between tenofovir co-administered antiretroviral drugs. Conclusions: Both prevalence and incidence of nephrotoxicity were low in patients receiving tenofovir in a non-selected clinical setting. Renal injury in patients receiving tenofovir seems associated with the presence of co-morbidities and with advanced HIV infection