256 research outputs found
The removal of Paraloid® coatings with aqueous based formulations. Practical case in frescoes from els Munts Roman villa (Catalonia)
This is the report of a practical case regarding the removal of Paraloid® B72 coatings from Roman frescoes. During the archaeological excavation, the paintings had been consolidated with the application of cotton gauze with an acrylic resin. The article presents the results regarding the effectiveness of the removal of the acrylic resin and the analytical assessment of the possible presence of residues on the work of art. The removal of the acrylic resin was carried out with an aqueous gelled system emulsified with only 10% solvent. The selection of the solvent phase presents fewer toxic alternatives to traditional solvents
Quorum-sensing regulates biofilm formation in Vibrio scophthalmi
Background: In a previous study, we demonstrated that Vibrio scophthalmi, the most abundant Vibrio species among the marine aerobic or facultatively anaerobic bacteria inhabiting the intestinal tract of healthy cultured turbot (Scophthalmus maximus), contains at least two quorum-sensing circuits involving two types of signal molecules (a 3-hydroxy-dodecanoyl-homoserine lactone and the universal autoinducer 2 encoded by luxS). The purpose of this study was to investigate the functions regulated by these quorum sensing circuits in this vibrio by constructing mutants for the genes involved in these circuits. Results. The presence of a homologue to the Vibrio harveyi luxR gene encoding a main transcriptional regulator, whose expression is modulated by quorumsensing signal molecules in other vibrios, was detected and sequenced. The V. scophthalmi LuxR protein displayed a maximum amino acid identity of 82% with SmcR, the LuxR homologue found in Vibrio vulnificus. luxR and luxS null mutants were constructed and their phenotype analysed. Both mutants displayed reduced biofilm formation in vitro as well as differences in membrane protein expression by mass-spectrometry analysis. Additionally, a recombinant strain of V. scophthalmi carrying the lactonase AiiA from Bacillus cereus, which causes hydrolysis of acyl homoserine lactones, was included in the study. Conclusions: V. scophthalmi shares two quorum sensing circuits, including the main transcriptional regulator luxR, with some pathogenic vibrios such as V. harveyi and V. anguillarum. However, contrary to these pathogenic vibrios no virulence factors (such as protease production) were found to be quorum sensing regulated in this bacterium. Noteworthy, biofilm formation was altered in luxS and luxR mutants. In these mutants a different expression profile of membrane proteins were observed with respect to the wild type strain suggesting that quorum sensing could play a role in the regulation of the adhesion mechanisms of this bacterium
Subjective Well-Being and Its Intrinsic and Extrinsic Motivational Correlates in High Performance Executives: A Study in Chilean Managers Empirically Revisiting the Bifactor Model
This study analyzes the relationship between work satisfaction, family satisfaction, and general well-being in high performance managers in Santiago, Chile. The importance of the satisfaction of intrinsic and extrinsic needs and motivations was examined to advance in the development of a positive organizational psychology, which investigates the factors that reinforce well-being. Seventy-five executives from large and medium-sized companies were surveyed and 8 in-depth interviews were carried out. The main predictors of well-being are, from family satisfaction, the family’s ability to cope with stress and, from work satisfaction, extrinsic aspects such as material conditions of the job and stability, and intrinsic aspects such as recognition and the ability to organize one’s own work. The more general regression model shows that extrinsic job and family satisfaction predict general well-being, not intrinsic satisfaction. The results are discussed in the framework of classical models of motivation, such as Herzberg’s, their relationship to Deci and Ryan’s self-determination theory, and the current study of well-being in organizations.This research was funded by SCIA ANID CIE160009, FONDECYT 1181533, FONDECYT 3210780, and Spanish MINECO Grant PID2020-115738GB-IOO
El camà a Europa: els serveis d'aprenentatge i recerca a les biblioteques de la UPC
The article shows how the library services of the Universitat Politècnica de Catalunya (UPC) manage change and explores the current opportunities available (university, electronic information, etc.) for converting the libraries into centres that actively support training and research at the university level. After providing information about the current university scenario, the article focuses on the road taken by the UPC libraries to overcome at both a conceptual and a practical level the major challenge of the millennium: transforming the traditional university library into a centre with resources for supporting academic teaching and research.L'article pretén mostrar com els serveis bibliotecaris de la Universitat Politècnica de Catalunya (UPC) gestionen els canvis i les oportunitats de l'entorn (universitat, informació electrònica, etc.) per convertir les seves biblioteques en centres actius de suport a l'aprenentatge i a la recerca università ria. Després de presentar l'escenari universitari actual s'explicarà el camà que han iniciat les biblioteques de la UPC per assolir conceptualment i en els seus serveis el primer gran repte del mil·lenni: transformar la biblioteca università ria tradicional en un veritable centre de recursos per al suport a la docència i la recerca acadèmiques
Off- and Online Heterosexual Dating Violence, Perceived Attachment to Parents and Peers and Suicide Risk in Young Women
Dating violence (DV) is a public health problem among young people, especially women. It involves violent acts towards one’s partner and occurs face-to-face (offline) or through the Internet (online). Offline DV is linked to suicidal ideation and attachment to parents and peers. Fewer studies analyze the psychological and social consequences of online DV. This study tests the link between young women’s DV victimization (off- and online), suicide risk (SR), and parent and peer support in a sample of young Spanish females (N = 1227) (Mage=19, SD = 2.82; range = 13–28). Results confirm that compared to non-victims off- and online DV increase suicidal thoughts and attempts. This effect is stronger for victims of both types of DV (thoughts: OR offline DV = 3.11; CI95% 2.06, 4.69; OR online DV = 2.37; CI95% 1.69, 3.32; OR off-online DV = 4.19 CI95% 2.44, 7.17) (attempts: OR offline DV = 4.02; CI95% 1.83, 8.81; OR online DV = 3.69; CI95% 1.96, 7.01; OR off-online DV = 10.55 CI95% 2.56, 44.43). Mediation and moderation models were used to assess the effect of perceived attachment of parents and friends in DV victims and SR. Mediation analyses indicated that perceived attachment and proximity to parents and peers reduces the impact of DV on SR. Moderation analyses showed that a high level of perceived peer attachment reduces the effect of offline DV on SR. Regarding off-online DV, a high level of perceived parent attachment mitigates suicide risk. Loneliness, lack of care from loved ones, and thwarted belongingness increase suicidal thoughts in DV victims. Peers and parents’ proximity may prevent risk behaviors in DV victims.This research was funded by CONICYT 2017/Doctorado en el Extranjero Becas Chile/2017, grant number 72180394 to Marcela Gracia Leiva, and by Basque government Post–Doctoral Scholarship to Alicia Puente MartÃnez, POS_2019_2_0014; This study was partially funded by grant 2019/00184/001 awarded by the Junta of Castilla y León (Spain) to the Social Inclusion and Quality of Life (SIQoL) research group and by grant Culture, Cognition and Emotion. Ref GIC12/91 IT–666–13 and the University of the Basque Country and Basque Government [grant number: GIC12/91 IT–666–13]
Emotion Regulation Strategies in Educational, Work and Sport Contexts: An Approach in Five Countries
One of the greatest challenges in the domain of emotional regulation is comprehending the functionality of strategies and their utilization in various social contexts. In this sense, this study analyzes differences in the use and efficacy of regulation strategies, particularly of interpersonal strategies like altruism, social support, negotiation, mediation, regulation, and rituals, in samples of workers (N = 687) and students (N = 959) from Brazil, Chile, Cuba, Spain, and Uruguay, and athletes (N =144) from Spain. Participants answered questions pertaining to measures of affect or emotional regulation (MARS and ERQ self-regulation scales and EROS heteroregulation), as well as questions of a wellbeing scale (PHI) and questions related to emotional creativity (ECI), humor styles (HSQ), and adjustment to stress. Athletes reported less emotional discharge, use of humor, and affection, and greater confrontation and use of rituals than students and workers. A congruent relationship was found between the use of functional strategies (like direct coping, distraction, reevaluation, and active physiological regulation) and adjustment to stress, well-being, and creativity. Seeking social support, negotiation, and, to an extent, altruism, confirmed their predicted adaptive character. Mediation and delegation did not confirm their predicted adaptive character. Rumination, social comparison, rituals, confrontation, and suppression were maladaptive for workers and students, but the first four strategies were functional for athletes, who display a higher self-control and a more team-oriented and competitive emotional culture. Finally, the results show that adaptive regulation strategies mediate the relationship between well-being and adjustment to stress
Lesiones cerebrales captantes de gadolinio en el brote de los pacientes con esclerosis múltiple
Esclerosis múltiple; Brote; Resonancia magnéticaEsclerosi múltiple; Brot; Imatge per ressonà ncia magnèticaMultiple sclerosis; Outbreak; Magnetic resonance imagingObjective
To study the clinico-radiological paradox in multiple sclerosis (MS) relapse by analyzing the number and location of gadolinium-enhanced (Gd+) lesions on brain MRI before methylprednisolone (MP) treatment.
Methods
We analyzed brain MRI from 90 relapsed MS patients in two Phase IV multicenter double-blind randomized clinical trials that showed the noninferiority of different routes and doses of MP administration. A 1.5- or 3-T brain MRI was performed at baseline before MP treatment and within 15 days of symptom onset. The number and location of Gd+ lesions were analyzed. Associations were studied using univariate analysis.
Results
Sixty-two percent of patients had at least 1 Gd+ brain lesion; the median number was 1 (interquartile range 0–4), and 41% of patients had 2 or more lesions. The most frequent location of Gd+ lesions was subcortical (41.4%). Gd+ brain lesions were found in 71.4% of patients with brainstem-cerebellum symptoms, 57.1% with spinal cord symptoms and 55.5% with optic neuritis (ON). Thirty percent of patients with brain symptoms did not have Gd+ lesions, and only 43.6% of patients had symptomatic Gd+ lesions. The univariate analysis showed a negative correlation between age and the number of Gd+ lesions (p = 0.002).
Conclusion
Most patients with relapse showed several Gd+ lesions on brain MRI, even when the clinical manifestation was outside of the brain. Our findings illustrate the clinico-radiological paradox in MS relapse and support the value of brain MRI in this scenario.Objetivo
Estudiar la paradoja clÃnico-radiológica en el brote de la esclerosis múltiple (EM) mediante el análisis de lesiones captantes de gadolinio (Gd+) en la RM cerebral antes del tratamiento con metilprednisolona (MP).
Métodos
Analizamos la RM cerebral basal de 90 pacientes con EM en brote de 2 ensayos clÃnicos aleatorizados multicéntricos fase IV que demostraron la no inferioridad de diferentes vÃas y dosis de MP, realizadas antes del tratamiento con MP y en los 15 dÃas siguientes a la aparición de los sÃntomas. Se analizaron el número y la localización de las lesiones Gd+. Se estudiaron las asociaciones mediante análisis univariado.
Resultados
El 62% de los pacientes tenÃa al menos una lesión Gd+ cerebral y el 41% de los pacientes tenÃa 2 o más lesiones. La localización más frecuente fue la subcortical (41,4%). Se encontraron lesiones Gd+ cerebrales en el 71,4% de los pacientes con sÃntomas de tronco cerebral o cerebelo, en el 57,1% con sÃntomas medulares y en el 55,5% con neuritis óptica. El 30% de los pacientes con sÃntomas cerebrales no tenÃan lesiones Gd+ y sólo el 4,.6% de los pacientes tenÃan lesiones Gd+ sintomáticas. El análisis univariante mostró una correlación negativa entre la edad y el número de lesiones Gd+ (p = 0,002).
Conclusiones
La mayorÃa de los pacientes en brote mostraron varias lesiones Gd+ en la RM cerebral, incluso cuando la manifestación clÃnica fue medular u óptica. Nuestros hallazgos ilustran la paradoja clÃnico-radiológica en el brote de la EM y apoyan el valor de la RM cerebral en este escenario.This work was supported in part by the Ministry of Health of Spain (grant numbers EC07/90278 and EC11/132) and personal grant Rio Hortega CM19/00042 to LMA
Salud mental: las prácticas como campo inter de problemas en la formación del psicólogo
A partir de la Ley Nacional 26.657 (2010) se pone en marcha en Argentina una polÃtica de Salud Mental que innova en el concepto de la salud mental, al proponer la atención del padecimiento desde abordajes intersectoriales, interdisciplinarios, abiertos, comunitarios, con un enfoque de derechos humanos, e implica redefinir el lugar de los actores y las prácticas en relación a la salud mental.
En el presente trabajo abordamos el paradigma de los derechos humanos como ordenador de esta nueva concepción, punto de partida que pone en crisis el andamiaje conceptual, profesional, institucional, incluyendo la formación del psicólogo.
Describimos los cambios en la formación profesional, y la incorporación de las prácticas como eje transversal en la formación del psicólogo en las evaluaciones de las carreras de grado.
Pasamos de una polÃtica que producÃa vÃctimas despojadas de derechos, a pensar una polÃtica que debe des-victimizar, a la par que actuar para no victimizarla nuevamente. Esto va a implicar una revisión de un conjunto muy vasto de prácticas. Analizamos la resignificación de las prácticas como campo inter de problemas (atravesamientos inter: subjetivo, disciplinario, de saberes, etc.).
En este gran escenario es que situamos la escena de la formación del psicólogo.As of Law 26.657 (2010), a Mental Health policy is launched in Argentina that innovates in the concept of mental health, by proposing care for the condition from intersectoral, interdisciplinary, open, community approaches, with a focus on human rights, and implies redefining the place of actors and practices in relation to mental health.
In this paper we approach the paradigm of human rights as the computer of this new conception, a starting point that puts in crisis the conceptual, professional, institutional scaffolding, including the training of the psychologist.
We describe the changes in professional training, and the incorporation of practices as a transversal axis in the training of the psychologist in the evaluations of undergraduate degrees.
We went from a policy that produced victims stripped of rights, to thinking of a policy that should de-victimize, at the same time as acting so as not to victimize them again. This is going to involve a review of a very vast set of practices. We analyze the redefinition of practices as an inter field of problems (inter: subjective, disciplinary, knowledge, etc.) It is in this great scenario that we place the scene of the training of the psychologist.Facultad de PsicologÃ
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