Recurrent Pneumonia in Children: A Reasoned Diagnostic Approach and a Single Centre Experience

Recurrent pneumonia (RP), i.e., at least two episodes of pneumonia in one year or three episodes ever with intercritical radiographic clearing of densities, occurs in 7.7%-9% of children with community-acquired pneumonia. In RP, the challenge is to discriminate between children with self-limiting or minor problems, that do not require a diagnostic work-up, and those with an underlying disease. The aim of the current review is to discuss a reasoned diagnostic approach to RP in childhood. Particular emphasis has been placed on which children should undergo a diagnostic work-up and which tests should be performed. A pediatric case series is also presented, in order to document a single centre experience of RP. A management algorithm for the approach to children with RP, based on the evidence from a literature review, is proposed. Like all algorithms, it is not meant to replace clinical judgment, but it should drive physicians to adopt a systematic approach to pediatric RP and provide a useful guide to the clinician

GO! geographical ontology

GO! (Geographical Ontology) ontology has been developed by Claudia Corcione, Paola De Caro and Silvia naro, with the collaboration of Diego Magro, Timothy Tambassi and Maurizio Lana for the research project \u201cGeolat \u2013 geography for Latin literature\u201d. It describes the geographical locations, with a particular attention to the description of the Ancient World, especially to give the opportunity of having a link between the places mentioned in the texts, especially ancient, and their identification and correspondence with contemporary ones. For classical scholars this correspondence of ancient / contemporary modelling is of undisputed interest, both for the study of the habits of the most ancient peoples, and for the most various themes of literary interest. Through ontologies you can build maps of the ancient world and compare them to contemporary ones, annotate historical, geographical, cultural details connected to the place, indicate in which ancient text the place is mentioned and as which author discloses the details. These are just some ideas for research that can be developed, but the scenario that opens through these connections will be much larger. The GO! modules contain numerous classes and relations and differ in the specific entities defined in them, and are connected by a Top Level ontology - GO TOP ( http://purl.org/geolit/GO-TOP ): \u2022 an ontology that describes the physical and natural places ( http://purl.org/geolit/GO-PHY ) \u2022 an anthropic ontology, in which are specified all administrative bodies and artifacts created by human activity ( http://purl.org/geolit/GO-HUM )an \u2022 an ontology for the ancient world, which describes the specific aspects ( http://purl.org/geolit/GO-FAR ), where FAR means For Ancient Resources. The GO! ontology serves as an information base for the platform of the project GeoLat. The GO! modelling choices took into account the needs which the ontology must meet, allowing to add a range of additional information about the geographical place, through the inclusion of ad hoc relationships, in particular it is possible to express: \u2022 the correspondence with the places listed by Pleiades (historical online gazetteer http://pleiades.stoa.org/) \u2022 the physical and cultural characteristics shown in the Barrington Atlas \u2022 the source where the ancient place is mentioned (with philological reference) \u2022 the geographical coordinates of corresponding contemporary sites \u2022 a description of historical events (wars, defeats ...) \u2022 the changes of the place (e.g. a village which becomes a city) \u2022 the hypotesized location of imaginary places (such as Hades) \u2022 the physical and geopolitical description of the place These are only some of the potentialities of the GO! ontology, which incorporates some standard ontologies (for example GeoSPARQL), so as to be more easily shared and reused, because the quality of the ontology and the project in its entirety resides in its widespread use, in order to become a benchmark for the projects that link to the geographical description