Additional file 2: of Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus

Table S3. Association results for the 52 previously known SLE risk loci in the Spain GWAS. Table S4. Pathway association results after combining the two SLE cohorts (combined raw p value <0.05). Table S5. List of biological pathways significantly associated with ST8SIA4 gene network. Table S6. List of biological pathways significantly associated with ARHGAP27 gene network. (XLSX 48 kb

Additional file 1: of Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus

Table S1. Epidemiological features from the Spain GWAS cohort. Figure S1. Principal component analysis of the Spain GWAS cohort. Figure S2. Quantile-quantile(Q-Q) plots of observed and expected -log10(p values) of association between SNP genotype and SLE risk. Table S2. Epigenetic regulatory data associated with GRB2 risk locus. Figure S3. Regional association plot for the association with SLE risk independent of GRB2 SNP rs36023980. Figure S4. GRB2 gene expression during human B cell differentiation. (DOCX 627 kb